Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hayato Kuroiwa"'
Publikováno v:
Neurological Sciences. 32:1-7
Dopaminergic neurons are selectively vulnerable to oxidative stress and inflammatory attack. The neuronal cell loss in the substantia nigra is associated with a glial response composed markedly of activated microglia and, to a lesser extent, of react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b5ce919edf964ddf0a5dcaddd2b519
https://doi.org/10.1007/s10072-010-0424-0
https://doi.org/10.1007/s10072-010-0424-0
Publikováno v:
Advanced Materials. 31:1805661
Photofunctional compounds have emerged as critically important materials for both fundamental studies and industrial applications. Control of the thermal decoloration speed to within several seconds while sustaining satisfactory photochromic colorabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7402a02b781f98b1e2d1609b9f8e3e9f
https://doi.org/10.1002/adma.201805661
https://doi.org/10.1002/adma.201805661
Publikováno v:
Metabolic Brain Disease. 25:177-183
We investigated the biochemical alterations of the striatum of mice subjected to seven experimental schedules with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (MPTP) treatment. The mice were treated intraperitoneally (i.p.) with MPTP (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170f2d380974e2568b42e548402ec838
https://doi.org/10.1007/s11011-010-9195-9
https://doi.org/10.1007/s11011-010-9195-9
Autor:
Hayato Kuroiwa, Jiro Kasahara, Hiroto Uchida, Hiroyuki Kato, Tatsuya Tsukada, Tsutomu Araki, Ryohei Yano, Hironori Yokoyama
Publikováno v:
Metabolic Brain Disease. 25:135-143
We investigated the therapeutic effect of zonisamide against 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice, using Western blot analysis, immunohistochemistry and behavioral test. Our Western blot analysis and immunohistoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a81d2a3388db45545f1989dcea780a
https://doi.org/10.1007/s11011-010-9191-0
https://doi.org/10.1007/s11011-010-9191-0
Autor:
Hayato Kuroiwa, Naoto Kadoguchi, Ryohei Yano, Takuya Oshikawa, Hironori Yokoyama, Hiroyuki Kato, Tsutomu Araki
Publikováno v:
Cellular and Molecular Neurobiology. 29:769-777
Dysfunction of the proteasome has been suggested to contribute in the degeneration of nigrostriatal dopaminergic neurons. Here, we investigated to determine whether systematic administration of proteasome inhibitor, carbobenzoxy-L: -gamma-t-butyl-L:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148c9d8b8bc29942c5bdd1fcfcfa8a83
https://doi.org/10.1007/s10571-009-9402-6
https://doi.org/10.1007/s10571-009-9402-6
Publikováno v:
Journal of Molecular Neuroscience. 39:211-219
Zonisamide, an anti-convulsant drug, has recently been shown to exert beneficial effects in Parkinson's disease (PD). However, actual pathophysiological mechanism underlying the anti-parkinsonian effect of zonisamide remains uncertain. Here we tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5589bebc99272e144682de7dddfb963c
https://doi.org/10.1007/s12031-009-9181-z
https://doi.org/10.1007/s12031-009-9181-z
Publikováno v:
Neurological Sciences. 29:293-301
Parkinson's disease (PD) is the second most frequent neurodegenerative disorder after Alzheimer's disease. The main clinical features of PD include tremor, bradykinesia, rigidity and postural instability. The primary pathology of PD is degeneration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39995c94c647f25c4adf7c1fa69e05d
https://doi.org/10.1007/s10072-008-0986-2
https://doi.org/10.1007/s10072-008-0986-2
Autor:
Hironori Yokoyama, Hiroto Uchida, Hiroyuki Kato, Hayato Kuroiwa, Tsutomu Araki, Tatsuya Tsukada
Publikováno v:
Journal of Neuroscience Research.
An excessive expression of poly(ADP-ribose)polymerase (PARP) has been demonstrated to play a key role in the pathogenesis of Parkinson's disease (PD). Here we investigated the therapeutic effect of the PARP inhibitor benzamide against 1-methyl-4-phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19515ec37b197a088e1fb84b9ca57b8f
https://doi.org/10.1002/jnr.22310
https://doi.org/10.1002/jnr.22310
Autor:
Hironori Yokoyama, Ryohei Yano, Hayato Kuroiwa, Tatsuya Tsukada, Hiroto Uchida, Hiroyuki Kato, Jiro Kasahara, Tsutomu Araki
Publikováno v:
Metabolic Brain Disease. 26:95-95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ab89484081ab04731c5e6d6e33cba5
https://doi.org/10.1007/s11011-010-9228-4
https://doi.org/10.1007/s11011-010-9228-4
Autor:
Takuya Oshikawa, Hayato Kuroiwa, Ryohei Yano, Hironori Yokoyama, Naoto Kadoguchi, Hiroyuki Kato, Tsutomu Araki
Publikováno v:
Cellular & Molecular Neurobiology; Jul2009, Vol. 29 Issue 5, p769-777, 9p