Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Hayato, Murakoshi"'
Autor:
Tomohiro Akahoshi, Hiroyuki Gatanaga, Nozomi Kuse, Takayuki Chikata, Madoka Koyanagi, Naoki Ishizuka, Chanson J Brumme, Hayato Murakoshi, Zabrina L Brumme, Shinichi Oka, Masafumi Takiguchi
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009177 (2020)
HIV-1 strains harboring immune escape mutations can persist in circulation, but the impact of selection by multiple HLA alleles on population HIV-1 dynamics remains unclear. In Japan, HIV-1 Reverse Transcriptase codon 135 (RT135) is under strong immu
Externí odkaz:
https://doaj.org/article/cf317fa4c7d4460eb38d3f3929d01091
Autor:
Hayato Murakoshi, Madoka Koyanagi, Tomohiro Akahoshi, Takayuki Chikata, Nozomi Kuse, Hiroyuki Gatanaga, Sarah L. Rowland-Jones, Shinichi Oka, Masafumi Takiguchi
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 103-112 (2018)
Background: HLA-B*35 is an HLA allele associated with rapid progression to AIDS. However, a mechanism underlying the detrimental effect of HLA-B*35 on disease outcome remains unknown. Recent studies demonstrated that most prevalent subtype HLA-B*35:0
Externí odkaz:
https://doaj.org/article/77b93fe6d9ad49a2aa0150caa1395dab
Autor:
Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, Masafumi Takiguchi
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-14 (2018)
Abstract Background Development of AIDS vaccines for effective prevention of circulating HIV-1 is required, but no trial has demonstrated definitive effects on the prevention. Several recent T-cell vaccine trials showed no protection against HIV-1 ac
Externí odkaz:
https://doaj.org/article/88f6db15ff354ba384804dfa920b05d9
Autor:
Yehia S. Mohamed, Nicola J. Borthwick, Nathifa Moyo, Hayato Murakoshi, Tomohiro Akahoshi, Francesca Siliquini, Zara Hannoun, Alison Crook, Peter Hayes, Patricia E. Fast, Gaudensia Mutua, Walter Jaoko, Sandra Silva-Arrieta, Anuska Llano, Christian Brander, Masafumi Takiguchi, Tomáš Hanke
Publikováno v:
Vaccines, Vol 8, Iss 2, p 260 (2020)
Sub-Saharan Africa carries the biggest burden of the human immunodeficiency virus type 1 (HIV-1)/AIDS epidemic and is in an urgent need of an effective vaccine. CD8+ T cells are an important component of the host immune response to HIV-1 and may need
Externí odkaz:
https://doaj.org/article/153ce30639e44cfdbf69e802818a6554
Autor:
Yu Zhang, Takayuki Chikata, Nozomi Kuse, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
Publikováno v:
Journal of virology. 96(22)
HLA-B57 is a relatively rare allele around world and the strongest protective HLA allele in Caucasians and African black individuals infected with HIV-1. Previous studies suggested that the advantage of this allele in HIV-1 disease progression is due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656e68a57aaa2a3c11fb054102395af6
https://pubmed.ncbi.nlm.nih.gov/36326273
https://pubmed.ncbi.nlm.nih.gov/36326273
Autor:
Hung The Nguyen, Nozomi Kuse, Yu Zhang, Hayato Murakoshi, Yosuke Maeda, Yoshiko Tamura, Rie Maruyama, Giang Van Tran, Trung Vu Nguyen, Kinh Van Nguyen, Shinichi Oka, Takayuki Chikata, Masafumi Takiguchi
Publikováno v:
Journal of Virology. 96
It is expected that HIV-1-specific CD8 + T cells that effectively suppress HIV-1 replication will contribute to HIV-1 vaccine development and therapy to achieve an HIV cure. T cells specific for protective epitopes were identified in HIV-1 subtype B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0a30fd628a592f7d3c416b6e16b046a
https://doi.org/10.1128/jvi.00811-22
https://doi.org/10.1128/jvi.00811-22
Autor:
Nicola Borthwick, Zhansong Lin, Tomohiro Akahoshi, Anuska Llano, Sandra Silva-Arrieta, Tina Ahmed, Lucy Dorrell, Christian Brander, Hayato Murakoshi, Masafumi Takiguchi, Tomáš Hanke
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176418 (2017)
BackgroundFine definition of targeted CD8+ T-cell epitopes and their human leucocyte antigen (HLA) class I restriction informs iterative improvements of HIV-1 T-cell vaccine designs and may predict early vaccine success or failure. Here, lymphocytes
Externí odkaz:
https://doaj.org/article/6b0b641ccd194fe08a5a2148f32bb9c4
Autor:
Nozomi Kuse, Tomohiro Akahoshi, Hayato Murakoshi, Chengcheng Zou, Mohamed Ali Borghan, Takayuki Chikata, Masafumi Takiguchi, Giang Van Tran, Kinh Van Nguyen, Trung Vu Nguyen
Publikováno v:
AIDS (London, England)
Objective The mechanism explaining the role of detrimental HLA alleles in HIV-1 infections has been investigated in very few studies. HLA-A*29:01-B*07:05-C*15:05 is a detrimental haplotype in HIV-1 subtype A/E-infected Vietnamese individuals. The acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0011497543e3eccb28cbebbcb72737f2
https://doi.org/10.1097/qad.0000000000002704
https://doi.org/10.1097/qad.0000000000002704
Autor:
Yu Zhang, Takayuki Chikata, Nozomi Kuse, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac14cc79b08d73e19dc8af7731d49a70
https://doi.org/10.2139/ssrn.4153445
https://doi.org/10.2139/ssrn.4153445
Autor:
K James, Nozomi Kuse, Hiroyuki Gatanaga, Takayuki Chikata, Hayato Murakoshi, Shinichi Oka, Sarah Rowland-Jones, Masafumi Takiguchi, Tomohiro Akahoshi
Publikováno v:
Journal of Virology
Although mutant-specific T cells are elicited in some individuals infected with HIV-1 mutant viruses, the detailed characteristics of these T cells remain unknown. A recent study showed that the accumulation of strains expressing Nef135F, which were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08858d8f88fc64ebe8234235d0f6ba2
https://doi.org/10.1128/jvi.01259-21
https://doi.org/10.1128/jvi.01259-21