TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function

Autor: Jose Ursic-Bedoya, Isabelle Doignon, Hayat Simerabet, Dominique Rainteau, Doris Cassio, Nicolas Kahale, Anne Davit-Spraul, Thierry Tordjmann, Grégory Merlen, Lydie Humbert, Catherine Guettier, Julien Gautherot, Valeska Bidault-Jourdainne, Christoph Ullmer, Isabelle Garcin, Noémie Péan, Klaus Ebnet, Zahra Tanfin

Publikováno v: Gut
Gut, BMJ Publishing Group, 2019, 69 (1), pp.146-157. ⟨10.1136/gutjnl-2018-316975⟩
Gut, 2019, 69 (1), pp.146-157. ⟨10.1136/gutjnl-2018-316975⟩

ObjectiveWe explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA overload through the regulation of biliary epithelium permeability.DesignExperime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660294abb0fa3eb398b53de0626d479f
https://hal.umontpellier.fr/hal-03356970