Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Hayat Onyuksel"'
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 23, Iss 1 (2020)
Traditional systemic chemotherapy involves the wide distribution of drug molecules in the body, causing toxic side effects in the healthy tissues and limiting the therapeutic dose required at the site of drug action. In order to decrease side effects
Externí odkaz:
https://doaj.org/article/16a602555a4c4b56884c11b63bde1c08
Autor:
Fatemeh Bahadori, Aydan Dag, Hakan Durmaz, Nese Cakir, Hayat Onyuksel, Umit Tunca, Gulacti Topcu, Gurkan Hizal
Publikováno v:
Polymers, Vol 6, Iss 1, Pp 214-242 (2014)
Two amphiphilic block copolymers using hydrophobic poly(ε-caprolactone) (PCL) and hydrophilic poly(ethylene glycol) (PEG) were successfully synthesized. One of them is an (A-b-B)4 type star polymer [(PCL-b-PEG)4] and the other one is a Y-shaped PEG
Externí odkaz:
https://doaj.org/article/308477f93a9f4a57bf33d9e8fcee7a27
Publikováno v:
Toxics, Vol 6, Iss 1, p 7 (2017)
Self-assembly systems (SAS) mainly consist of micelles, and liposomes are the classes of Nano Drug Delivery Systems with superior properties compared to traditional therapeutics in targeting cancer tumors. All commercially available nano-formulations
Externí odkaz:
https://doaj.org/article/af9fabf80ede4fd2a9be805f91331249
Autor:
Seema Saksena, Shubha Priyamvada, Pradeep K. Dudeja, Dulari Jayawardena, Anoop Kumar, Arivarasu Natarajan Anbazhagan, Hayat Onyuksel
Publikováno v:
Nanomedicine (Lond)
Aim: To evaluate the efficacy of locally delivered nanomedicine, vasoactive intestinal peptide in sterically stabilized micelles (VIP-SSM) to the colon and conduct in vitro release studies of a potential oral formulation. Materials & methods: Intraco
Autor:
Melda Altikatoglu, Zahra Eskandari, Fatemeh Bahadori, Vildan Betul Yenigun, Abdurrahim Kocyigit, Hayat Onyuksel
Publikováno v:
Records of Natural Products, Vol 13, Iss 5, Pp 390-404 (2019)
This study aims to investigate the effects of co-administration of nano-Curcumin on anticancer effect of nano-Pirarubicin considering the fact that the clinical use of Pirarubicin and other anthracyclines has been limited by development of multidrug
Autor:
Hayat Onyuksel, Karina Esparza
Publikováno v:
International Journal of Pharmaceutics. 556:21-29
The purpose of this work was to develop a practical and scalable method to encapsulate the hydrophobic antibiotic thiostrepton (TST) in sterically stabilized micelles (SSM). Using the conventional method of thin-film hydration, we encapsulated up to
Autor:
Mert Celikten, Hayat Onyuksel, Abdurrahim Kocyigit, Melda Altikatoglu Yapaoz, Zahra Eskandari, Fatemeh Bahadori, Vildan Betul Yenigun
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 162
In this study the chemotherapeutic agent Pirarubicin (PRB) which is known for its serious side effects was actively targeted to the breast cancer cells by uploading it to the biocompatible and biodegradable Sterically Stabilized Micelles (SSMs) made
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2000
Sterically stabilized micelle (SSM) is a self-assembled nanoparticle ideal for the delivery of therapeutic peptides. The PEGylated phospholipid forming the particle, DSPE-PEG
Autor:
Richard D. Minshall, Aleksandra Stojanovic-Terpo, Xiaoping Du, Misuk Bae, Maricela Castellon, Luiza Rusu, Hayat Onyuksel
Publikováno v:
The FASEB Journal. 33
Publikováno v:
The FASEB Journal. 33