Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Hayat Mokrani"'
1
Akademický článek
Endothelial dysfunction and hypercoagulability in severe sickle-cell acute chest syndrome
Autor: Etienne-Marie Jutant, Guillaume Voiriot, Vincent Labbé, Laurent Savale, Hayat Mokrani, Patrick Van Dreden, Grigorios Gerotziafas, Muriel Fartoukh
Publikováno v: ERJ Open Research, Vol 7, Iss 4 (2021)
Rationale Acute pulmonary hypertension (PH) may develop during sickle-cell acute chest syndrome (ACS), and is associated with an increased mortality. Its mechanisms remain poorly known. We questioned whether there is endothelial dysfunction and hyper
Externí odkaz: https://doaj.org/article/64aa1ca62fd146aca7959879c2ef5b56
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2
Akademický článek
Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia
Autor: Pierre Hirsch, Yanyan Zhang, Ruoping Tang, Virginie Joulin, Hélène Boutroux, Elodie Pronier, Hannah Moatti, Pascale Flandrin, Christophe Marzac, Dominique Bories, Fanny Fava, Hayat Mokrani, Aline Betems, Florence Lorre, Rémi Favier, Frédéric Féger, Mohamad Mohty, Luc Douay, Ollivier Legrand, Chrystèle Bilhou-Nabera, Fawzia Louache, François Delhommeau
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Pre-leukaemic clones, together with the propensity to cause disease in mice, are characterized by appearing early in myeloid leukaemia and being found at relapse. Here, the authors identify clones in human samples and find that they are characterized
Externí odkaz: https://doaj.org/article/2dbbe918315649bd816bccb6c1b9c78c
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3
Endothelial dysfunction and hypercoagulability in severe sickle-cell acute chest syndrome
Autor: Laurent Savale, Etienne-Marie Jutant, Muriel Fartoukh, Vincent Labbé, Guillaume Voiriot, Patrick Van Dreden, Grigorios T. Gerotziafas, Hayat Mokrani
Publikováno v: ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, European Respiratory Society, 2021, 7 (4), pp.00496-2021. ⟨10.1183/23120541.00496-2021⟩
ERJ Open Research, Vol 7, Iss 4 (2021)
ERJ Open Research, 2021, 7 (4), pp.00496-2021. ⟨10.1183/23120541.00496-2021⟩
Rationale Acute pulmonary hypertension (PH) may develop during sickle-cell acute chest syndrome (ACS), and is associated with an increased mortality. Its mechanisms remain poorly known. We questioned whether there is endothelial dysfunction and hyper
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6004834c6a7dba2d4e3303018a5e784
http://europepmc.org/articles/PMC8666627
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4
The formin DIAPH1 (mDia1) regulates megakaryocyte proplatelet formation by remodeling the actin and microtubule cytoskeletons
Autor: Yann Lécluse, Jiajia Pan, I. Badirou, Hayat Mokrani, Susan M. Kitchen-Goosen, Arthur S. Alberts, Larissa Lordier, Shuh Narumiya, Yunhua Chang, Deborah Meyran, Philippe Rameau, William Vainchenker
Publikováno v: Blood. 124:3967-3977
Megakaryocytes are highly specialized precursor cells that produce platelets via cytoplasmic extensions called proplatelets. Proplatelet formation (PPF) requires profound changes in microtubule and actin organization. In this work, we demonstrated th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5780152ef152b34af0f4f74d32549d9b
https://doi.org/10.1182/blood-2013-12-544924
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5
Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia
Autor: Hannah Moatti, François Delhommeau, Rémi Favier, Mohamad Mohty, Chrystele Bilhou-Nabera, Fawzia Louache, Virginie Joulin, Ruoping Tang, Aline Betems, Elodie Pronier, Florence Lorre, Pascale Flandrin, Ollivier Legrand, Fanny Fava, Christophe Marzac, Pierre Hirsch, Frédéric Féger, Hélène Boutroux, Hayat Mokrani, Luc Douay, Dominique Bories, Yanyan Zhang
Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2016, pp.12475. ⟨10.1038/ncomms12475⟩
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, 2016, 7, pp.12475. ⟨10.1038/ncomms12475⟩
In acute myeloid leukaemia (AML) initiating pre-leukaemic lesions can be identified through three major hallmarks: their early occurrence in the clone, their persistence at relapse and their ability to initiate multilineage haematopoietic repopulatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2957c610d80a444affe3137ac192aba
https://doi.org/10.1038/ncomms12475
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6
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors
Autor: Olivier A. Bernard, François Delhommeau, Eric Solary, Frédéric Pendino, Nicole Casadevall, Lucy A. Godley, Bruno Carbonne, Elodie Pronier, Jérôme Larghero, Aparna Vasanthakumar, William Vainchenker, Barbara da Costa Reis Monte Mor, Carole Almire, Isabelle Plo, Jean-Luc Ravanat, Aline Massé, Jean-Pierre Le Couedic, Nathalie Droin, Hayat Mokrani, Audrey Simon
Publikováno v: Blood
Blood, American Society of Hematology, 2011, 118 (9), pp.2551-2555. ⟨10.1182/blood-2010-12-324707⟩
Blood, 2011, 118 (9), pp.2551-2555. ⟨10.1182/blood-2010-12-324707⟩
TET2 converts 5-methylcytosine to 5-hydroxymethylcytosine (5-hmC) in DNA and is frequently mutated in myeloid malignancies, including myeloproliferative neoplasms. Here we show that the level of 5-hmC is decreased in granulocyte DNA from myeloprolife
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8513cb25b0561594616b3336123fb76
https://doi.org/10.1182/blood-2010-12-324707
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7
A Clinic-Genetic Score for Risk Assessment of Recurrent Venous Thrombo Embolism
Autor: C Delassasseigne, L Benzerara, Ismail Elalamy, Hela Ketatni, G.T. Gerotziafas, Manuella Onambele, Hayat Mokrani, Virginie Planche
Publikováno v: Blood. 128:1428-1428
Background Current risk assessment models to predict the risk of recurrent venous thromboembolism (VTE) in an individual patient (i.e Vienna Pedicitive Model, DASH score) include clinical and biochemical parameters and have showed discrimination valu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d18a650cf90b6e9b3791cebff6fb7faf
https://doi.org/10.1182/blood.v128.22.1428.1428
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8
Modelization of the procoagulant properties of cancer cells and the alterations of the effectiveness of the anticoagulant agents
Autor: Elisabeth Mbemba, Konstantinos N. Syrigos, Aurélie Rousseau, Hayat Mokrani, Grigoris T. Gerotziafas, Ismail Elalamy, Patrick Van Dreden, Annette K. Larsen
Publikováno v: Journal of Clinical Oncology. 34:e23094-e23094
e23094Background: The pathogenesis of the prothrombotic state in cancer is complex and may alter the efficiency of the antithrombotic agents but not all mechanisms are entirely understood. In the p...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8f9fe99aa8d86a033fe9d98b3a25802
https://doi.org/10.1200/jco.2016.34.15_suppl.e23094
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10
Inhibition of TET2 Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine Disturbs Myelopoiesis and Granulo-Monocytic Differentiation
Autor: Jean-Luc Ravanat, William Vainchenker, Carole Almire, Barbara da Costa Reis Monte Mor, Elodie Pronier, Aline Massé, Audrey Simon, Hayat Mokrani, François Delhommeau, Nicole Casadevall, Isabelle Plo, Eric Solary
Publikováno v: Blood. 116:1584-1584
Abstract 1584 TET2, a gene frequently mutated in myeloid malignancies, encodes an oxygenase that may convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in hematopoietic cells. Using high performance liquid chromatography coupled to tand
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72e59977c441018d7292724f3e1b0543
https://doi.org/10.1182/blood.v116.21.1584.1584
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