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Leucine 434 is essential for docosahexaenoic acid-induced augmentation of L-glutamate transporter current.

Autor: Takahashi K; Laboratory of Neuropharmacology, Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Chen L; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Sayama M; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Wu M; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Hayashi MK; Department of Food Science and Nutrition, Faculty of Food and Health Sciences, Showa Women's University, Tokyo, Japan., Irie T; Laboratory of Neuropharmacology, Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Ohwada T; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Sato K; Laboratory of Neuropharmacology, Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan. Electronic address: kasato@nihs.go.jp.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Jan; Vol. 299 (1), pp. 102793. Date of Electronic Publication: 2022 Dec 09.

Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro.

Autor: Togo K; Department of Neurology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.; Division of Stem Cell Research, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan., Fukusumi H; Division of Stem Cell Research, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan., Shofuda T; Division of Stem Cell Research, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan., Ohnishi H; Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Gunma, 371-8514, Japan., Yamazaki H; Department of Neurobiology and Behavior, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan.; Faculty of Social Welfare, Gunma University of Health and Welfare, Maebashi, Gunma, 371-0823, Japan., Hayashi MK; School of Medicine, International University of Health and Welfare, Narita, Chiba, 286-8686, Japan.; Department of Food Science and Nutrition, Faculty of Food and Health Sciences, Showa Women's University, Setagaya-ku, Tokyo, 154-8533, Japan., Kawasaki N; Laboratory of Biopharmaceutical and Regenerative Sciences, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, 230-0045, Japan., Takei N; Department of Brain Tumor Biology, Brain Research Institute, Niigata University, Niigata, Niigata, 951-8585, Japan., Nakazawa T; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, 565-0871, Japan.; Department of Bioscience, Faculty of Life Sciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan., Saito Y; Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, 739-8521, Japan., Baba K; Department of Neurology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan., Hashimoto H; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, 565-0871, Japan.; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Suita, Osaka, 565-0871, Japan.; Division of Bioscience, Institute for Datability Science, Osaka University, Suita, Osaka, 565-0871, Japan.; Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Osaka, 565-0871, Japan.; Department of Molecular Pharmaceutical Sciences, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan., Sekino Y; Endowed Laboratory of Human Cell-Based Drug Discovery, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Shirao T; Department of Neurobiology and Behavior, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan., Mochizuki H; Department of Neurology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan., Kanemura Y; Division of Regenerative Medicine, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, Osaka, 540-0006, Japan. kanemura.yonehiro.hk@mail.hosp.go.jp.; Department of Neurosurgery, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan. kanemura.yonehiro.hk@mail.hosp.go.jp.

Publikováno v: Molecular brain [Mol Brain] 2021 Oct 11; Vol. 14 (1), pp. 149. Date of Electronic Publication: 2021 Oct 11.