Leucine 434 is essential for docosahexaenoic acid-induced augmentation of L-glutamate transporter current.

Autor: Takahashi K; Laboratory of Neuropharmacology, Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Chen L; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Sayama M; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Wu M; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Hayashi MK; Department of Food Science and Nutrition, Faculty of Food and Health Sciences, Showa Women's University, Tokyo, Japan., Irie T; Laboratory of Neuropharmacology, Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Ohwada T; Laboratory of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Sato K; Laboratory of Neuropharmacology, Division of Pharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan. Electronic address: kasato@nihs.go.jp.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Jan; Vol. 299 (1), pp. 102793. Date of Electronic Publication: 2022 Dec 09.

Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro.

Autor: Togo K; Department of Neurology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan.; Division of Stem Cell Research, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan., Fukusumi H; Division of Stem Cell Research, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan., Shofuda T; Division of Stem Cell Research, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan., Ohnishi H; Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Gunma, 371-8514, Japan., Yamazaki H; Department of Neurobiology and Behavior, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan.; Faculty of Social Welfare, Gunma University of Health and Welfare, Maebashi, Gunma, 371-0823, Japan., Hayashi MK; School of Medicine, International University of Health and Welfare, Narita, Chiba, 286-8686, Japan.; Department of Food Science and Nutrition, Faculty of Food and Health Sciences, Showa Women's University, Setagaya-ku, Tokyo, 154-8533, Japan., Kawasaki N; Laboratory of Biopharmaceutical and Regenerative Sciences, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Kanagawa, 230-0045, Japan., Takei N; Department of Brain Tumor Biology, Brain Research Institute, Niigata University, Niigata, Niigata, 951-8585, Japan., Nakazawa T; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, 565-0871, Japan.; Department of Bioscience, Faculty of Life Sciences, Tokyo University of Agriculture, Setagaya-ku, Tokyo, 156-8502, Japan., Saito Y; Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, 739-8521, Japan., Baba K; Department of Neurology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan., Hashimoto H; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, 565-0871, Japan.; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Suita, Osaka, 565-0871, Japan.; Division of Bioscience, Institute for Datability Science, Osaka University, Suita, Osaka, 565-0871, Japan.; Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Osaka, 565-0871, Japan.; Department of Molecular Pharmaceutical Sciences, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan., Sekino Y; Endowed Laboratory of Human Cell-Based Drug Discovery, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Shirao T; Department of Neurobiology and Behavior, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan., Mochizuki H; Department of Neurology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan., Kanemura Y; Division of Regenerative Medicine, Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka, Osaka, 540-0006, Japan. kanemura.yonehiro.hk@mail.hosp.go.jp.; Department of Neurosurgery, National Hospital Organization Osaka National Hospital, Osaka, Osaka, 540-0006, Japan. kanemura.yonehiro.hk@mail.hosp.go.jp.

Publikováno v: Molecular brain [Mol Brain] 2021 Oct 11; Vol. 14 (1), pp. 149. Date of Electronic Publication: 2021 Oct 11.

Hyaluronan synthesis supports glutamate transporter activity.

Autor: Hayashi MK; Medical School, International University of Health and Welfare, Narita, Chiba, Japan.; Division of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.; Department of Pharmacology, Keio University School of Medicine, Tokyo, Japan.; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Nishioka T; Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan., Shimizu H; Division of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Takahashi K; Division of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Kakegawa W; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Mikami T; Department of Environmental and Life Sciences, Toyohashi University of Technology, Toyohashi, Aichi, Japan., Hirayama Y; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan., Koizumi S; Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan., Yoshida S; Department of Environmental and Life Sciences, Toyohashi University of Technology, Toyohashi, Aichi, Japan., Yuzaki M; Department of Physiology, Keio University School of Medicine, Tokyo, Japan., Tammi M; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland., Sekino Y; Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan., Kaibuchi K; Department of Cell Pharmacology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan., Shigemoto-Mogami Y; Division of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan., Yasui M; Department of Pharmacology, Keio University School of Medicine, Tokyo, Japan., Sato K; Division of Pharmacology, Laboratory of Neuropharmacology, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan.

Publikováno v: Journal of neurochemistry [J Neurochem] 2019 Aug; Vol. 150 (3), pp. 249-263. Date of Electronic Publication: 2019 Jul 09.

Machine learning approach for recognition and morphological analysis of isolated astrocytes in phase contrast microscopy.

Autor: Yakovlev, Egor V.¹ (AUTHOR) yakov.egor@gmail.com, Simkin, Ivan V.¹ (AUTHOR), Shirokova, Anastasiya A.¹ (AUTHOR), Kolotieva, Nataliya A.^1,2 (AUTHOR), Novikova, Svetlana V.^1,2 (AUTHOR), Nasyrov, Artur D.¹ (AUTHOR), Denisenko, Ilya R.¹ (AUTHOR), Gursky, Konstantin D.¹ (AUTHOR), Shishkov, Ivan N.¹ (AUTHOR), Narzaeva, Diana E.^1,2 (AUTHOR), Salmina, Alla B.^1,2 (AUTHOR), Yurchenko, Stanislav O.¹ (AUTHOR), Kryuchkov, Nikita P.¹ (AUTHOR) kruchkov_nkt@mail.ru

Publikováno v: Scientific Reports. 4/29/2024, Vol. 14 Issue 1, p1-14. 14p.

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