Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hayase Hakariya"'
Autor:
Hayase Hakariya, Frank Moriarty, Akihiko Ozaki, Shai Mulinari, Hiroaki Saito, Tetsuya Tanimoto
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 7, Pp n/a-n/a (2024)
Abstract Regulatory authorities must balance ensuring evidence of efficacy and safety of new drugs. Various regulatory pathways, such as the accelerated approval program in the United States (US), allow authorities to quickly approve drugs for severe
Externí odkaz:
https://doaj.org/article/6bfe692511564447955ac6c3ffe2f993
Publikováno v:
Journal of General and Family Medicine, Vol 25, Iss 1, Pp 77-80 (2024)
Abstract Background In this digital age, social networks may offer an avenue for individuals to obtain drugs illicitly beyond the prescribed amount. Users on X (Twitter)® have ingeniously fabricated fashionable accessories that employ prescription d
Externí odkaz:
https://doaj.org/article/5b1cfea5ab3b484789be626faaf26f92
Publikováno v:
JMIR Formative Research, Vol 8, p e54023 (2024)
BackgroundNonmedical use of prescription drugs can cause overdose; this represents a serious public health crisis globally. In this digital era, social networking services serve as viable platforms for illegal acquisition of excessive amounts of medi
Externí odkaz:
https://doaj.org/article/f04774d5019447978d10571afe0beefa
Publikováno v:
YAKUGAKU ZASSHI. 142:901-904
Non-medical use of prescription medications is a serious public health crisis. The black market for prescription medications should be routinely surveyed to encourage their appropriate use. Herein, we focused on Twitter to investigate the possibility
Autor:
Hayase Hakariya, Shinichi Sato, Misao Takemoto, Ippei Takashima, Naotaka Noda, Motonari Uesugi
Publikováno v:
Chemical Communications. 57(12):1470-1473
This report describes the development of a non-genetic cell-surface modification method, in which a self-assembling small molecule is combined with Halo-tag proteins. Cell-surface functionalization with cancer-linked extracellular proteins led to enh
Autor:
Shinichi Sato, Yousuke Katsuda, Kenji Yatsuzuka, Tomoki Kida, Masatora Fukuda, Kathleen Beverly Pe, Hayase Hakariya
Publikováno v:
Nucleic Acids Research
Imaging the dynamics of proteins in living cells is a powerful means for understanding cellular functions at a deeper level. Here, we report a versatile method for spatiotemporal imaging of specific endogenous proteins in living mammalian cells. The
Autor:
Eiry Kobatake, Koki Yoshimoto, Yumie Tokunaga, Yoshie Koyama, Teiko Shibata-Seki, Hayase Hakariya, Momoko Yoshioka, Yong Chen, Yasumasa Mashimo, Motonari Uesugi, Li Liu, Siew-Eng How, Shiho Terada, Christopher Fockenberg, Risako Sakai, Ken-ichiro Kamei, Toshihiro Akaike
Publikováno v:
J Vis Exp
Cellular microenvironments consist of a variety of cues, such as growth factors, extracellular matrices, and intercellular interactions. These cues are well orchestrated and are crucial in regulating cell functions in a living system. Although a numb
Autor:
Daisuke Kobayashi, Attayeb Mohsen, Masakazu Sekijima, Tomoki Ito, M. Michael Gromiha, Masahiro Mochizuki, Mika Sakamoto, Kenji Mizuguchi, Modong Tan, Hideaki Umeyama, Nobuaki Yasuo, Shuntaro Chiba, Shogo Suzuki, Takashi Ishida, Kazuyoshi Ikeda, Daisuke Kihara, Yoshitaka Moriwaki, Yutaka Akiyama, Reiji Teramoto, A. Mary Thangakani, Shintaro Minami, Vipul Gupta, Mitsuo Iwadate, Chioko Nagao, Takaaki Ichikawa, Kazuki Yamamoto, Masahito Ohue, Itsuo Nakane, Kei Yura, Tatsuya Okuno, George Chikenji, Masahiro Kawatani, Kun Yi Hsin, Sakurako Takashina, Takatsugu Hirokawa, Woong-Hee Shin, Devadasan Velmurugan, Hayase Hakariya, Chandrasekaran Ramakrishnan, Ryunosuke Yoshino, Hironori K. Nakamura, Philip Prathipati, Nobuaki Miura, Hiroaki Kitano, Sergey Zozulya, Mari Ito, Akiko Higuchi, Teruki Honma, Petro Borysko, Keita Oda, Anastasiia Gryniukova, Nanako Uchida, Kentaroh Kudoh
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Potential inhibitors of a target biomolecule, NAD-dependent deacetylase Sirtuin 1, were identified by a contest-based approach, in which participants were asked to propose a prioritized list of 400 compounds from a designated compound library contain