Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Hayase, Shisa"'
Autor:
Michiko Ehara, Motoo Kitano, Hayase Shisa, Masato Hirano, Jun-ichi Tanuma, Aiko Sugiyama, Hiroshi Hiai, Motohiko Nagayama, Hirohiko Suwa, Masahiro Sugimoto, Tomonari Muraki, Kouji Kawarada
Publikováno v:
Oncology Reports
Susceptibly to the induction of rat tongue cancer (TC) by oral 4-nitroquinoline 1-oxide (4NQO) exposure is a polygenic trait. Among several quantitative trait loci identified by crosses between TC-susceptible Dark Agouti (DA) rats and TC-resistant Wi
Autor:
Kotaro Ogawa, Jun-ichi Tanuma, Motoo Kitano, Ichiro Semba, Hayase Shisa, Yoshikazu Hirayama, Masato Hirano
Publikováno v:
Oral Oncology. 42:710-717
Summary We previously reported that susceptibility to 4-nitroquinoline 1-oxide (4NQO)-induced tongue cancer in Dark-Agouti (DA) and Wistar/Furth (WF) rats was determined by a number of quantitative trait loci. In this article, we further scrutinized
Autor:
Hiroshi Hiai, Atsushi Tamura, Lingmin Lu, Yoshibumi Matsushima, Masayoshi Tachibana, Hayase Shisa
Publikováno v:
Experimental Animals. 55:91-95
Increasing exposure to environmental endocrine disruptor, xeno-estrogen, is a serious hazard to male reproductive activity. To explore possible genetic control in susceptibility to xeno-estrogen, the weight reduction of testes induced by the continuo
Autor:
Yoshikazu Hirayama, Ichiro Semba, Hayase Shisa, Masato Hirano, Kotaro Ogawa, Hiroshi Hiai, Motoo Kitano, Jun-ichi Tanuma
Publikováno v:
Medical Principles and Practice. 14:297-305
Objective: This study aims to elucidate the genetic basis of predisposition to 4-nitroquinoline 1-oxide (4NQO)-induced tongue cancers (TCs). Materials and Methods: We have reported that inbred Dark-Agouti (DA) strain rats were highly susceptible to 4
Autor:
Ichiro Semba, Jun-ichi Tanuma, Hayase Shisa, Hiroshi Hiai, Masato Hirano, Motoo Kitano, Shigetaka Nagaoka
Publikováno v:
International Journal of Cancer. 102:638-642
Rats of the DA strain are highly susceptible to 4NQO-induced TCs, whereas WF rats are barely susceptible. In (DA x WF)F2 rats, 5 QTL, Tscc1-5, are responsible for most of the phenotypic variations, though they do not account for all of the phenotypic
Autor:
Osamu Ogawa, Yoshihiro Yamada, Tomomi Kamba, Hiroshi Hiai, Shin Higashi, Toshiyuki Kamoto, Hayase Shisa
Publikováno v:
The American Journal of Pathology. 159:2347-2353
FUBI (failure of ureteric bud invasion) is a highly inbred strain of mouse with a high spontaneous incidence of uni- or bilateral renal agenesis (60%). Bilateral renal agenesis is lethal within 2 days after birth. The primary defect of FUBI is failur
Autor:
Hayase Shisa, Kazunori Onoé, Machiko Mishima, Taiki Morohashi, Manabu Ato, Hiroshi Hiai, Noriko Arase, Mari Hirano
Publikováno v:
Journal of Clinical and Experimental Hematopathology. 41:61-68
Using SL/Kh mice and AKR/J mice, which are animal models for spontaneous pre-B-cell leukemia and thymic lymphoma, respectively, we studied the protective influence of allogeneic bone marrow transplantation (BMT) and the induction of tolerance to Mls-
Publikováno v:
Journal of Experimental Animal Science. 41:68-77
Summary Oral administration of 4-nitroquinoline 1-oxide (4NQO) to rats induced a high incidence of tongue carcinomas (TCs). The inbred Dark-Agouti (DA) strain of rats showed much higher susceptibility to 4NQO-induced TCs than the Wistar-Furth (WF) st
Publikováno v:
British Journal of Cancer
Oral administration of propylnitrosourea (PNU) in drinking water induces high incidence of lympho-haemopoietic malignancies in rats. Previously we reported that F344 strain rats were highly susceptible to T-lymphomas, and LE/Stm rats, to erythro- or