Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hayao Matsuhashi"'
Autor:
Hayao Matsuhashi, Qiaogong Su
Publikováno v:
Organic Process Research & Development. 25:627-631
Unexpected failures of a Heck reaction in the lab led to the detection of 5-hydroperoxy-1-methyl-2-pyrrolidinone (NMP-5-OOH) in the cosolvent 1-methyl-2-pyrrolidinone (NMP). This hydroperoxide, for...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7d60fed56e428358b37248ac34ce0f1
https://doi.org/10.1021/acs.oprd.0c00432
https://doi.org/10.1021/acs.oprd.0c00432
Autor:
David E. White, Frederick G. Vogt, Lianming Wu, Connie Ye, Gerald J. Terfloth, Hayao Matsuhashi
Publikováno v:
Journal of Mass Spectrometry. 47:836-844
While the occurrence of desulfurization of phosphorothioate oligonucleotides in solution is well established, this study represents the first attempt to investigate the basis of the unexpected desulfurization via the net sulfur-by-oxygen (S-O) replac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10206db38326286f00ca43ecd0fd265
https://doi.org/10.1002/jms.3022
https://doi.org/10.1002/jms.3022
Autor:
Richard M. Goodman, Hao Yin, Susan V. Downing, Alan Joseph Hennessy, Eric A. Voight, Jeffery L. Wood, Stacie Calad, Hayao Matsuhashi, Ilaria Giordano
Publikováno v:
Organic Letters. 12:3422-3425
An efficient enantioselective total synthesis of the potent antibiotic GSK966587 was accomplished. Highlights of the synthesis include two innovative Heck reactions, a highly selective zincate base directed ortho-metalation, Sharpless asymmetric epox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda8b886ffede4859a4b7a8eba64b638
https://doi.org/10.1021/ol101235f
https://doi.org/10.1021/ol101235f
Autor:
William M. Clark, Huan Wang, Doan Brian Daniel, Xi Ouyang, Hayao Matsuhashi, Steven N. Goodman
Publikováno v:
Tetrahedron. 65:6291-6303
Two stereoselective syntheses of SB-462795, a highly potent cathepsin K inhibitor, are described. Both routes feature a C5–C6 disconnection by ring closing metathesis to construct an azepane ring and are amenable to large-scale manufacturing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f446df72477928a1704261f785712192
https://doi.org/10.1016/j.tet.2009.06.022
https://doi.org/10.1016/j.tet.2009.06.022
Autor:
Hayao Matsuhashi, Kousei Shimada
Publikováno v:
Tetrahedron. 58:5619-5626
Chemical transformation of Leustroducsin H to Leustroducsin B has been successfully accomplished in 11 steps including enzymatic hydrolysis of phosphate ester. The process described here enables to differentiate all hydroxyl groups, amino and phospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1231e980b8be046ac2bfe38162236e84
https://doi.org/10.1016/s0040-4020(02)00528-8
https://doi.org/10.1016/s0040-4020(02)00528-8
Autor:
Tamejiro Hiyama, Kazunori Hirabayashi, Atsunori Mori, Masaki Shimizu, Hayao Matsuhashi, Akinori Fujita, Makoto Tanaka
Publikováno v:
Organometallics. 15:5762-5765
Palladium-catalyzed cross-coupling reaction of optically active (2-cyclohexenyl)difluorophenylsilane with 4-iodoacetophenone in the presence of tetrabutylammonium fluoride furnishes the corresponding cross-coupled product with retention of the stereo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f14b77f560c6c7583b1ab822f637d35
https://doi.org/10.1021/om960750a
https://doi.org/10.1021/om960750a
Autor:
Manabu Kuroboshi, Hayao Matsuhashi, Hideaki Ohmura, Ken-ichi Goda, Yasuo Hatanaka, Makoto Tanaka, Tamejiro Hiyama
Publikováno v:
Journal of Organometallic Chemistry. 499:167-171
A palladium complex with an optically active ligand catalyzes asymmetric hydrosilylation of 1,3-dienes using difluoro(phenyl)silane to give optically active allyl difluoro(phenyl)silanes in good enantiomeric excess.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42e4ab273dbb0d1760bb1fac1d0d808e
https://doi.org/10.1016/0022-328x(95)00311-d
https://doi.org/10.1016/0022-328x(95)00311-d
Autor:
Lianming, Wu, David E, White, Connie, Ye, Frederick G, Vogt, Gerald J, Terfloth, Hayao, Matsuhashi
Publikováno v:
Journal of mass spectrometry : JMS. 47(7)
While the occurrence of desulfurization of phosphorothioate oligonucleotides in solution is well established, this study represents the first attempt to investigate the basis of the unexpected desulfurization via the net sulfur-by-oxygen (S-O) replac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33c5d1b10a4be1f37e2fa4a02c8c6d73
https://pubmed.ncbi.nlm.nih.gov/22791250
https://pubmed.ncbi.nlm.nih.gov/22791250
Publikováno v:
Tetrahedron Letters. 35:6507-6510
A variety of alkyltrifluorosilanes were found to couple with aryl halides in the presence of Pd(PPh3)4 catalyst and tetrabutylammonium fluoride (TBAF) to give the corresponding cross-coupled products in moderate to good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73bad7b3e2ac119396a8f9b1d9d9c3ea
https://doi.org/10.1016/s0040-4039(00)78258-x
https://doi.org/10.1016/s0040-4039(00)78258-x
Publikováno v:
ChemInform. 26
A variety of alkyltrifluorosilanes were found to couple with aryl halides in the presence of Pd(PPh3)4 catalyst and tetrabutylammonium fluoride (TBAF) to give the corresponding cross-coupled products in moderate to good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::929c41e570b41a45e398c1d4e2a3e2d4
https://doi.org/10.1002/chin.199504098
https://doi.org/10.1002/chin.199504098