Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hay Bruce Allan"'
Publikováno v:
Tetrahedron Letters. 35:5809-5812
Oxidation of substituted thietanes 1a, b, and 6 with m-chloroperoxybenzoic acid preferentially gives the corresponding cis-sulfoxides with modest diastereoselectivity. Selective oxidation of the trans over the cis diastereomeric pairs of sulfoxides 2
Publikováno v:
ChemInform. 25
Oxidation of substituted thietanes 1a, b, and 6 with m-chloroperoxybenzoic acid preferentially gives the corresponding cis-sulfoxides with modest diastereoselectivity. Selective oxidation of the trans over the cis diastereomeric pairs of sulfoxides 2
Autor:
Alan Robertson, Hay Bruce Allan, Todd W. Siegel, Dennis J. Pelletier, Murray Marianne C, Rona A. Nardone, Frank M. DiCapua, Bridget Mccarthy Cole, Glen W. Kirk, Anthony P. Ricketts
Publikováno v:
ChemInform. 33
The first potent small molecule sst2 antagonists are reported. Altering known sst2 agonist molecules yielded compounds with high sst2 binding affinity and full antagonist activity. Compound 7a, for example, displaced somatostatin binding to the sst2
Publikováno v:
Journal of the American Society of Brewing Chemists. 49:115-118
Autor:
Julie Jia Li Hawkins, James J. Valentine, Katherine T. Landschulz, Laurie C. Warren, Michael D. Robbins, Ing-Kae Wang, H. James Harwood, Timothy A. Subashi, Kieran F. Geoghegan, Stephen F. Petras, Donghui Xia, Alison H. Varghese, Lorraine D. Shelly, Hay Bruce Allan
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 326(3)
Sterol regulatory element-binding proteins (SREBPs) are major transcriptional regulators of cholesterol, fatty acid, and glucose metabolism. Genetic disruption of SREBP activity reduces plasma and liver levels of cholesterol and triglycerides and ins
Autor:
Alison H. Varghese, Lorraine D. Shelly, Julie Jia Li Hawkins, Barbara Abrams, H. James Harwood, Laurie C. Warren, Michael D. Robbins, Angela Xia, Katherine T. Landschulz, Stephen F. Petras, James J. Valentine, Allice Y. Zumbrunn, Jennifer A. Van Camp, Hay Bruce Allan
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(16)
The discovery and efficacy of a series of potent aminopyrrolidineamide-based inhibitors of sterol regulatory element binding protein site-1 protease is described.
Publikováno v:
Journal of the American Society of Brewing Chemists. 52:54-56
Autor:
Bridget Mccarthy Cole, Rona A. Nardone, Anthony P. Ricketts, Dennis J. Pelletier, Murray Marianne C, Hay Bruce Allan, Frank M. DiCapua, Alan Robertson, Glen W. Kirk, Todd W. Siegel
Publikováno v:
Bioorganicmedicinal chemistry letters. 11(20)
The first potent small molecule sst2 antagonists are reported. Altering known sst2 agonist molecules yielded compounds with high sst2 binding affinity and full antagonist activity. Compound 7a, for example, displaced somatostatin binding to the sst2
Autor:
John W. Homiski, Hay Bruce Allan
Publikováno v:
Journal of Agricultural and Food Chemistry. 39:1732-1734