Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hawraa Bzeih"'
Autor:
Angelina Staudt, Olga Ratai, Aicha Bouzouina, Claudia Fecher-Trost, Ahmed Shaaban, Hawraa Bzeih, Alexander Horn, Ali H. Shaib, Margarete Klose, Veit Flockerzi, Marcel A. Lauterbach, Jens Rettig, Ute Becherer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Both paralogs of the calcium-dependent activator protein for secretion (CAPS) are required for exocytosis of synaptic vesicles (SVs) and large dense core vesicles (LDCVs). Despite approximately 80% sequence identity, CAPS1 and CAPS2 have distinct fun
Externí odkaz:
https://doaj.org/article/5286869c7a7e4edfb1a509880282ac20
Endocytosis of Cytotoxic Granules Is Essential for Multiple Killing of Target Cells by T Lymphocytes
Autor:
Emmanuelle Cordat, Elmar Krause, Jens Rettig, Hsin-Fang Chang, Mahantappa Halimani, Hawraa Bzeih, Claudia Schirra, Praneeth Chitirala, Varsha Pattu
Publikováno v:
The Journal of Immunology. 197:2473-2484
CTLs are serial killers that kill multiple target cells via exocytosis of cytotoxic granules (CGs). CG exocytosis is tightly regulated and has been investigated in great detail; however, whether CG proteins are endocytosed following exocytosis and co
Autor:
Elmar Krause, Hsin-Fang Chang, Jens Rettig, Hawraa Bzeih, Keerthana Ravichandran, Varsha Pattu, Praneeth Chitirala, Marwa Sleiman, Ulrike Hahn
Publikováno v:
Cellular and Molecular Life Sciences
Cytotoxic T lymphocytes patrol our body in search for infected cells which they kill through the release of cytotoxic substances contained in cytotoxic granules. The fusion of cytotoxic granules occurs at a specially formed contact site, the immunolo
Autor:
Jens Rettig, Hsin-Fang Chang, Mahantappa Halimani, Elmar Krause, Min Ming, Hawraa Bzeih, Varsha Pattu, Claudia Schirra, Ulrike Hahn, Lisa Weins
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology
Frontiers in Immunology
Cytotoxic T lymphocytes (CTLs) form an integral part of the adaptive immune system. Their main function is to eliminate bacteria- and virus-infected target cells by releasing perforin and granzymes (the lethal hit) contained within lytic granules, at