Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hawley Rigsby"'
Autor:
Rachel S Resop, Rémi Fromentin, Daniel Newman, Hawley Rigsby, Larisa Dubrovsky, Michael Bukrinsky, Nicolas Chomont, Alberto Bosque
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008679 (2020)
Antiretroviral drugs that target various stages of the Human Immunodeficiency Virus (HIV) life cycle have been effective in curbing the AIDS epidemic. However, drug resistance, off-target effects of antiretroviral therapy (ART), and varying efficacy
Externí odkaz:
https://doaj.org/article/4e087863075b4755a801652b83c88dd8
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102605 (2014)
Although studies have addressed the exhaustion of the host's immune response to HCV and its role in treatment, there is little information about the possible contribution of innate immunity to treatment-induced clearance. We hypothesized that because
Externí odkaz:
https://doaj.org/article/ba2cc9e356c7476586676af37a269331
Autor:
Marianne Harris, Mark A. Brockman, Rémi Fromentin, Zabrina L. Brumme, Bradley R Jones, Art F. Y. Poon, Hanwei Sudderuddin, Natalie N. Kinloch, Aniqa Shahid, Rachel L Miller, Olivia Tsai, Chanson J. Brumme, Bruce Ganase, Jeffrey B. Joy, Nicolas Chomont, Hawley Rigsby
Publikováno v:
Journal of Virology. 94
The HIV reservoir, which comprises diverse proviruses integrated into the genomes of infected, primarily CD4+ T cells, is the main barrier to developing an effective HIV cure. Our understanding of the genetics and dynamics of proviruses persisting wi
Autor:
Bradley R, Jones, Rachel L, Miller, Natalie N, Kinloch, Olivia, Tsai, Hawley, Rigsby, Hanwei, Sudderuddin, Aniqa, Shahid, Bruce, Ganase, Chanson J, Brumme, Marianne, Harris, Art F Y, Poon, Mark A, Brockman, Rémi, Fromentin, Nicolas, Chomont, Jeffrey B, Joy, Zabrina L, Brumme
Publikováno v:
J Virol
The HIV reservoir, which comprises diverse proviruses integrated into the genomes of infected, primarily CD4(+) T cells, is the main barrier to developing an effective HIV cure. Our understanding of the genetics and dynamics of proviruses persisting
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e102605 (2014)
PLoS ONE, Vol 9, Iss 7, p e102605 (2014)
Although studies have addressed the exhaustion of the host's immune response to HCV and its role in treatment, there is little information about the possible contribution of innate immunity to treatment-induced clearance. We hypothesized that because
Autor:
Jerry Pelletier, Denis Gaucher, Ryan D. Morin, Koren K. Mann, Randy D. Gascoyne, Nathalie A. Johnson, Joseph M. Connors, Marco A. Marra, Hawley Rigsby
Publikováno v:
Cancer Research. 74:959-959
Lymphomas are common (1/30 Canadians), but responses to chemotherapy depend on the tumour biology. We sequenced > 300 lymphomas at diagnosis and at relapse, identified FAS as a possible tumour suppressor gene and found that mutant FAS is associated w
Autor:
Ian Gaël Rodrigue-Gervais, Bernard Willems, Hawley Rigsby, Daniel Lamarre, Rafick-Pierre Sekaly, Loubna Jouan, Dominike Sauvé
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(6)
Although chronic viral infections have evolved mechanisms to interfere with aspects of pathogen recognition by dendritic cells (DCs), the role that these APCs play in virus-specific T cell exhaustion is unclear. Herein we report that NS3-dependent su
Autor:
Joseph M. Connors, Randy D. Gascoyne, Nathalie A. Johnson, Denis Gaucher, Ryan D. Morin, Hawley Rigsby, Marco A. Marra
Publikováno v:
Blood. 120:1549-1549
Abstract 1549 Introduction: We recently reported on recurrent genomic alterations present in genome, transcriptome or exome data from 127 cases of NHL (Morin et al. Nature. 2011 Jul 27;476:298–303). Our data suggests FAS acts as a tumor suppressor
Publikováno v:
Cytokine. 43:274
Autor:
Resop, Rachel S.1 (AUTHOR), Fromentin, Rémi2 (AUTHOR), Newman, Daniel1 (AUTHOR), Rigsby, Hawley2 (AUTHOR), Dubrovsky, Larisa1 (AUTHOR), Bukrinsky, Michael1 (AUTHOR), Chomont, Nicolas2 (AUTHOR), Bosque, Alberto1 (AUTHOR) abosque@email.gwu.edu
Publikováno v:
PLoS Pathogens. 8/13/2020, Vol. 16 Issue 8, p1-23. 23p.