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Akademický článek

Protein-observed (19)F-NMR for fragment screening, affinity quantification and druggability assessment.

Autor: Gee CT; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Arntson KE; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Urick AK; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Mishra NK; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Hawk LM; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Wisniewski AJ; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Pomerantz WC; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA.

Publikováno v: Nature protocols [Nat Protoc] 2016 Aug; Vol. 11 (8), pp. 1414-27. Date of Electronic Publication: 2016 Jul 14.

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Akademický článek

Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules.

Autor: Urick AK; Department of Chemistry, University of Minnesota , 207 Pleasant St. SE, Minneapolis, Minnesota 55455, United States., Hawk LM; Department of Chemistry, University of Minnesota , 207 Pleasant St. SE, Minneapolis, Minnesota 55455, United States., Cassel MK; Department of Chemistry, University of Minnesota , 207 Pleasant St. SE, Minneapolis, Minnesota 55455, United States., Mishra NK; Department of Chemistry, University of Minnesota , 207 Pleasant St. SE, Minneapolis, Minnesota 55455, United States., Liu S; Department of Chemistry, University of Massachusetts Boston , 100 Morrissey Boulevard, Boston, Massachusetts 02125, United States., Adhikari N; Lillehei Heart Institute , Department of Medicine, 2231 6th Street SE, Minneapolis, Minnesota 55455, United States., Zhang W; Department of Chemistry, University of Massachusetts Boston , 100 Morrissey Boulevard, Boston, Massachusetts 02125, United States., dos Santos CO; Cold Spring Harbor Laboratory , 1 Bungtown Road, Cold Spring Harbor, New York 11724, United States., Hall JL; Lillehei Heart Institute , Department of Medicine, 2231 6th Street SE, Minneapolis, Minnesota 55455, United States., Pomerantz WC; Department of Chemistry, University of Minnesota , 207 Pleasant St. SE, Minneapolis, Minnesota 55455, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2015 Oct 16; Vol. 10 (10), pp. 2246-56. Date of Electronic Publication: 2015 Jul 28.

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