Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Haw-Yuan Cheng"'
1
Akademický článek
Efficient in Utero Gene Transfer to the Mammalian Inner Ears by the Synthetic Adeno-Associated Viral Vector Anc80L65
Autor: Chin-Ju Hu, Ying-Chang Lu, Yi-Hsiu Tsai, Haw-Yuan Cheng, Hiroki Takeda, Chun-Ying Huang, Ru Xiao, Chuan-Jen Hsu, Jin-Wu Tsai, Luk H. Vandenberghe, Chen-Chi Wu, Yen-Fu Cheng
Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 493-500 (2020)
Sensorineural hearing loss is one of the most common sensory disorders worldwide. Recent advances in vector design have paved the way for investigations into the use of adeno-associated vectors (AAVs) for hearing disorder gene therapy. Numerous AAV s
Externí odkaz: https://doaj.org/article/3d99ac29290f4535b5ffc081bedfe891
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2
Akademický článek
Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation
Autor: Meng-Han Tsai, Haw-Yuan Cheng, Fang-Shin Nian, Chen Liu, Nian-Hsin Chao, Kuo-Liang Chiang, Shu-Fang Chen, Jin-Wu Tsai
Publikováno v: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract During brain development, the nucleus of migrating neurons follows the centrosome and translocates into the leading process. Defects in these migratory events, which affect neuronal migration, cause lissencephaly and other neurodevelopmental
Externí odkaz: https://doaj.org/article/5df5849e9cd34b418a022b70785d3207
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3
Akademický článek
Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome
Autor: Hsin-Yun Chang, Haw-Yuan Cheng, Ai-Ni Tsao, Chen Liu, Jin-Wu Tsai
Publikováno v: Frontiers in Molecular Neuroscience, Vol 12 (2019)
Kinesin-binding protein (KBP; KIF1BP; KIAA1279) functions as a regulator for a subset of kinesins, many of which play important roles in neural development. Previous studies have shown that KBP is expressed in nearly all tissue with cytoplasmic local
Externí odkaz: https://doaj.org/article/64cb0425036741f6ab9bcd41c1bb5a58
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8
Additional file 1 of Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation
Autor: Meng-Han Tsai, Haw-Yuan Cheng, Fang-Shin Nian, Liu, Chen, Nian-Hsin Chao, Kuo-Liang Chiang, Chen, Shu-Fang, Tsai, Jin-Wu
Additional file 1: Figure S1. BicD2 expression and cell distributions in the developing cortex subjected to BicD2 RNAi. Figure S2. Immunostaining of different markers in brain slices electroporated with Bicd2 K775X.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a686845d4a48a69a1f701d1cbe3fbe33
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