A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation

Autor: Schanin J, Gebremeskel S, Korver W, Falahati R, Butuci M, Haw TJ, Nair PM, Liu G, Hansbro NG, Hansbro PM, Evensen E, Brock EC, Xu A, Wong A, Leung J, Bebbington C, Tomasevic N, Youngblood BA

In addition to their well characterized role in mediating IgE-dependent allergic diseases, aberrant accumulation and activation of mast cells (MCs) is associated with many non-allergic inflammatory diseases, whereby their activation is likely trigger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::e4097a4dc1f78c44b70c414243787290
https://hdl.handle.net/10453/143336

Fibulin-1c regulates transforming growth factor–β activation in pulmonary tissue fibrosis

Autor: Liu, G, Cooley, MA, Jarnicki, AG, Borghuis, T, Nair, PM, Tjin, G, Hsu, AC, Haw, TJ, Fricker, M, Harrison, CL, Jones, B, Hansbro, NG, Wark, PA, Horvat, JC, Scott Argraves, W, Oliver, BG, Knight, DA, Burgess, JK, Hansbro, PM

Copyright: © 2019, American Society for Clinical Investigation. Tissue remodeling/fibrosis is a major feature of all fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). It is underpinned by accumulating extracellular matrix (ECM) prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::362506b0d155b11be4ee584aa9ef0a1a
https://hdl.handle.net/10453/137003

Toll-like receptors in COPD

Autor: Hansbro, PM, Haw, TJ, Starkey, MR, Miyake, K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::e7a5e3eb72734c77f6bafd0168c87ec7
https://hdl.handle.net/10453/144934

FIUBLIN-1C PLAYS CRITICAL ROLES IN LUNG REMODELLING IN IDIOPATHIC PULMONARY FIBROSIS

Autor: Liu, G, Cooley, MA, Jarnicki, AG, Hsu, AC-Y, Nair, PM, Haw, TJ, Tjin, G, Jones, B, Harrison, CL, Fricker, M, Inman, MD, Walker, MM, Horvat, JC, Oliver, BG, Argraves, WS, Knight, DA, Burgess, JK, Hansbro, PM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::b91a18c0922f18ca41965ee8939256c9
https://hdl.handle.net/10453/154574

Landscape fire smoke airway exposure impairs respiratory and cardiac function and worsens experimental asthma.

Autor: Gomez HM; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia., Haw TJ; Heart and Stroke Research Program, Hunter Medical Research Institute, New Lambton Heights, Newcastle, Australia; College of Health, Medicine, and Wellbeing, Centre of Excellence Newcastle Cardio-Oncology Research Group, University of Newcastle, Callaghan, Newcastle, Australia., Ilic D; Newcastle Institute for Energy and Resources, University of Newcastle, Callaghan, Australia., Robinson P; Newcastle Institute for Energy and Resources, University of Newcastle, Callaghan, Australia., Donovan C; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia; School of Life Sciences, University of Technology Sydney, Faculty of Science, Sydney, Australia., Croft AJ; Heart and Stroke Research Program, Hunter Medical Research Institute, New Lambton Heights, Newcastle, Australia; College of Health, Medicine, and Wellbeing, Centre of Excellence Newcastle Cardio-Oncology Research Group, University of Newcastle, Callaghan, Newcastle, Australia., Vanka KS; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia; Newcastle Institute for Energy and Resources, University of Newcastle, Callaghan, Australia., Small E; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia., Carroll OR; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia., Kim RY; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia; School of Life Sciences, University of Technology Sydney, Faculty of Science, Sydney, Australia., Mayall JR; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia., Beyene T; School of Medicine and Public Health, University of Newcastle and Asthma and Breathing Program, Hunter Medical Research Institute, Newcastle, Australia., Palanisami T; Global Innovative Centre for Advanced Nanomaterials, University of Newcastle, Callaghan, Australia., Ngo DTM; Heart and Stroke Research Program, Hunter Medical Research Institute, New Lambton Heights, Newcastle, Australia; College of Health, Medicine, and Wellbeing, Centre of Excellence Newcastle Cardio-Oncology Research Group, University of Newcastle, Callaghan, Newcastle, Australia., Zosky GR; Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, Australia; College of Health and Medicine, Tasmanian School of Medicine, University of Tasmania, Hobart, Australia., Holliday EG; School of Medicine and Public Health, University of Newcastle, Callaghan, Australia., Jensen ME; School of Medicine and Public Health, University of Newcastle and Asthma and Breathing Program, Hunter Medical Research Institute, Newcastle, Australia., McDonald VM; School of Medicine and Public Health, University of Newcastle and Asthma and Breathing Program, Hunter Medical Research Institute, Newcastle, Australia., Murphy VE; School of Medicine and Public Health, University of Newcastle and Asthma and Breathing Program, Hunter Medical Research Institute, Newcastle, Australia., Gibson PG; School of Medicine and Public Health, University of Newcastle and Asthma and Breathing Program, Hunter Medical Research Institute, Newcastle, Australia., Horvat JC; School of Biomedical Sciences and Pharmacy, University of Newcastle and Immune Health Program, Hunter Medical Research Institute, Newcastle, Australia. Electronic address: jay.horvat@newcastle.edu.au.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2024 Jul; Vol. 154 (1), pp. 209-221.e6. Date of Electronic Publication: 2024 Mar 19.