Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Havish S. Kantheti"'
Autor:
Havish S. Kantheti, Michael A. Hale, Shreoshi Pal Choudhuri, Huocong Huang, Xu-dong Wang, Yalda Zolghadri, Giulio Innamorati, Sai Prasada Rao Manikonda, Naviya Reddy, Sarthak Reddy, Rahul K. Kollipara, Valbona Lumani, Luc Girard, Yakov Bezrukov, Pavel Demenkov, Raymond J. MacDonald, Rolf A. Brekken, Yonghao Yu, Thomas M. Wilkie
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6619 (2024)
Diagnostic markers are desperately needed for the early detection of pancreatic ductal adenocarcinoma (PDA). We describe sets of markers expressed in temporal order in mouse models during pancreatitis, PDA initiation and progression. Cell type specif
Externí odkaz:
https://doaj.org/article/ca0ca2e8a45e4004ad47086feb150789
Autor:
Giulio Innamorati, Thomas M. Wilkie, Havish S. Kantheti, Maria Teresa Valenti, Luca Dalle Carbonare, Luca Giacomello, Marco Parenti, Davide Melisi, Claudio Bassi
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Mutations activating the α subunit of heterotrimeric Gs protein are associated with a number of highly specific pathological molecular phenotypes. One of the best characterized is the McCune Albright syndrome. The disease present
Externí odkaz:
https://doaj.org/article/84fdabee74354cff8a20371bb2e62283
Autor:
Nikolaus Schultz, Jedd D. Wolchok, Katherine S. Panageas, David B. Solit, Klaus J. Busam, Paul B. Chapman, Neal Rosen, Daniel G. Coit, Mary Susan Brady, Christopher A. Barker, Charlotte E. Ariyan, Suresh Nair, Parisa Momtaz, Michael A. Postow, Allison Betof Warner, Margaret K. Callahan, Penina Krieger, Jorge A. Rojas Zamalloa, Havish S. Kantheti, Francisco Sanchez-Vega, Arshi Arora, Walid K. Chatila, Alexander N. Shoushtari
MAF file
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a9a2d99f5c96ddbe11d990539abec6
https://doi.org/10.1158/1078-0432.22480406.v1
https://doi.org/10.1158/1078-0432.22480406.v1
Autor:
Nikolaus Schultz, Jedd D. Wolchok, Katherine S. Panageas, David B. Solit, Klaus J. Busam, Paul B. Chapman, Neal Rosen, Daniel G. Coit, Mary Susan Brady, Christopher A. Barker, Charlotte E. Ariyan, Suresh Nair, Parisa Momtaz, Michael A. Postow, Allison Betof Warner, Margaret K. Callahan, Penina Krieger, Jorge A. Rojas Zamalloa, Havish S. Kantheti, Francisco Sanchez-Vega, Arshi Arora, Walid K. Chatila, Alexander N. Shoushtari
Kaplan-Meier curves for overall survival. (A) PD-1 monotherapy by driver class. (B) nivolumab plus ipilimumab by driver class. (C) PD-1 monotherapy by primary site of melanoma. (D) nivolumab plus ipilimumab by primary site of melanoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b0a2b5b96e240e8cd3c25235e90d5b
https://doi.org/10.1158/1078-0432.22480412
https://doi.org/10.1158/1078-0432.22480412
Autor:
Nikolaus Schultz, Jedd D. Wolchok, Katherine S. Panageas, David B. Solit, Klaus J. Busam, Paul B. Chapman, Neal Rosen, Daniel G. Coit, Mary Susan Brady, Christopher A. Barker, Charlotte E. Ariyan, Suresh Nair, Parisa Momtaz, Michael A. Postow, Allison Betof Warner, Margaret K. Callahan, Penina Krieger, Jorge A. Rojas Zamalloa, Havish S. Kantheti, Francisco Sanchez-Vega, Arshi Arora, Walid K. Chatila, Alexander N. Shoushtari
Supplementary Data Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1586d38fc809bbe02e60f9a70a7b0f
https://doi.org/10.1158/1078-0432.22480409
https://doi.org/10.1158/1078-0432.22480409
Autor:
Nikolaus Schultz, Jedd D. Wolchok, Katherine S. Panageas, David B. Solit, Klaus J. Busam, Paul B. Chapman, Neal Rosen, Daniel G. Coit, Mary Susan Brady, Christopher A. Barker, Charlotte E. Ariyan, Suresh Nair, Parisa Momtaz, Michael A. Postow, Allison Betof Warner, Margaret K. Callahan, Penina Krieger, Jorge A. Rojas Zamalloa, Havish S. Kantheti, Francisco Sanchez-Vega, Arshi Arora, Walid K. Chatila, Alexander N. Shoushtari
Purpose:Cutaneous and unknown primary melanomas frequently harbor alterations that activate the MAPK pathway. Whether MAPK driver detection beyond BRAF V600 is clinically relevant in the checkpoint inhibitor era is unknown.Experimental Design:Patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ca3e4ba4ea1b8b5c63d384de1245d6
https://doi.org/10.1158/1078-0432.c.6530441.v1
https://doi.org/10.1158/1078-0432.c.6530441.v1
Autor:
Havish S. Kantheti, Ana Clara Azevedo-Pouly, Somayeh Layeghi-Ghalehsoukhteh, Bruce A. Posner, Huocong Huang, Shreoshi Pal Choudhuri, Raymond J. MacDonald, Hanspeter Niederstrasser, Victor Pashkov, Luc Girard, Rolf A. Brekken, Thomas M. Wilkie, Ozhan Ocal, Yalda Zolghadri
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
PDA is a major cause of US cancer-related deaths. Oncogenic Kras presents in 90% of human PDAs. Kras mutations occur early in pre-neoplastic lesions but are insufficient to cause PDA. Other contributing factors early in disease progression include ch
Autor:
Elena Faccenda, Adam J Pawson, Kirk M. Druey, David L. Roman, Mackenzie M. Spicer, Michael Spedding, Rory A. Fisher, Mohammed Alqinyah, Hoa Phan, Benita Sjögren, Christopher G. Sobey, Yalda Zolghadri, Arthur Christopoulos, Shelley B. Hooks, Simon D. Harding, Thiruma V. Arumugam, Laurie P. Sutton, Behirda Karaj, Stephen P.H. Alexander, Jae-Kyung Lee, Christopher R. Bodle, Peter Buneman, Eamonn Kelly, Zili Luo, Jörg Striessnig, Jane F. Armstrong, Jamie A. Davies, Vincent Shaw, Keqiang Xie, Shreoshi Pal Choudhuri, Katherine E. Squires, Luke D. Mascarenhas, Katelin E. Ahlers-Dannen, Harrison J. McNabb, Kyle J. Gerber, Menbere Wendimu, John A. Peters, Anthony P. Davenport, Doriano Fabbro, Somayeh Layeghi-Ghalehsoukhteh, Havish S. Kantheti, Emma L. Veale, Bandana Chakravarti, Thomas M. Wilkie, Carolina Montañez-Miranda, John R. Hepler, Kirill A. Martemyanov, Christopher Southan, John A. Cidlowski, Qian Zhang, Alistair Mathie, Josephine Buo Dagner, Osita W. Ogujiofor
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d71b6cad2f29e8755e256dd641b2af
Autor:
Carolina Montañez-Miranda, Mohammed Alqinyah, Thomas M. Wilkie, Benita Sjögren, David L. Roman, Somayeh Layeghi-Ghalehsoukhteh, Yalda Zolghadri, Osita W. Ogujiofor, John R. Hepler, Behirda Karaj, Shelley B. Hooks, Havish S. Kantheti, Menbere Wendimu, Rory A. Fisher, Jae-Kyung Lee, Katherine E. Squires, Qian Zhang, Bandana Chakravarti, Katelin E. Ahlers-Dannen, Keqiang Xie, Josephine Bou Dagher, Vincent Shaw, Christopher Bodle, Shreoshi Pal Choudhuri, Harrison J. McNabb, Kyle J. Gerber, Kirill A. Martemyanov, Mackenzie M. Spicer, Kirk M. Druey, Luke D. Mascarenhas, Hoa Phan Thi Nhu, Zili Luo, Laurie P. Sutton
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete
Autor:
Carolina Montañez-Miranda, Kirill A. Martemyanov, John R. Hepler, Yalda Zolghadri, Katelin E. Ahlers-Dannen, Luke D. Mascarenhas, Rory A. Fisher, Kirk M. Druey, Josephine Bou Dagher, Thomas M. Wilkie, Zili Luo, Behirda Karaj, Havish S. Kantheti, David L. Roman, Christopher Bodle, Shreoshi Pal Choudhuri, Kyle J. Gerber, Hoa Phan Thi Nhu, Jae-Kyung Lee, Menbere Wendimu, Katherine E. Squires, Laurie P. Sutton, Bandana Chakravarti, Shelley B. Hooks, Vincent Shaw, Mohammed Alqinyah, Keqiang Xie, Benita Sjögren, Mackenzie M. Spicer
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2020
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete