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Elevating microRNA levels by targeting biogenesis with steric-blocking antisense oligonucleotides.

Autor: Havens MA; Center for Genetic Diseases, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA havensmy@lewisu.edu hastingm@umich.edu.; Biology Department, Lewis University, Romeoville, Illinois 60446, USA.; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Hinrich AJ; Center for Genetic Diseases, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA., Rigo F; Ionis Pharmaceuticals, Carlsbad, California 92008, USA., Hastings ML; Center for Genetic Diseases, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA havensmy@lewisu.edu hastingm@umich.edu.; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

Publikováno v: RNA (New York, N.Y.) [RNA] 2024 Nov 18; Vol. 30 (12), pp. 1543-1553. Date of Electronic Publication: 2024 Nov 18.

Interactions of copper and copper chelate compounds with the amyloid beta peptide: An investigation into electrochemistry, reactive oxygen species and peptide aggregation.

Autor: Crnich E; Department of Biology, Lewis University, One University Pkwy, Romeoville, IL 60455, United States., Lullo R; Department of Biology, Lewis University, One University Pkwy, Romeoville, IL 60455, United States; Department of Chemistry, Lewis University, One University Pkwy, Romeoville, IL 60455, United States., Tabaka A; Department of Chemistry, Lewis University, One University Pkwy, Romeoville, IL 60455, United States., Havens MA; Department of Biology, Lewis University, One University Pkwy, Romeoville, IL 60455, United States., Kissel DS; Department of Chemistry, Lewis University, One University Pkwy, Romeoville, IL 60455, United States. Electronic address: kisselda@lewisu.edu.

Publikováno v: Journal of inorganic biochemistry [J Inorg Biochem] 2021 Sep; Vol. 222, pp. 111493. Date of Electronic Publication: 2021 May 29.

A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD.

Autor: Parnell SC; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, USA.; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA., Magenheimer BS; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, USA.; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA., Maser RL; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, USA.; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA.; Department of Clinical Laboratory Sciences, University of Kansas Medical Center, Kansas City, KS, USA., Pavlov TS; Division of Hypertension and Vascular Research, Henry Ford Hospital, Detroit, MI, USA., Havens MA; Department of Biology, Lewis University, Romeoville, IL, USA., Hastings ML; Department of Cell Biology and Anatomy, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA., Jackson SF; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA., Ward CJ; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA., Peterson KR; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, USA.; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA., Staruschenko A; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, USA., Calvet JP; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, USA.; The Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, KS, USA.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2018 Oct 01; Vol. 27 (19), pp. 3313-3324.

Targeting SR proteins improves SMN expression in spinal muscular atrophy cells.

Autor: Wee CD; Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America., Havens MA; Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America., Jodelka FM; Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America., Hastings ML; Department of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Dec 15; Vol. 9 (12), pp. e115205. Date of Electronic Publication: 2014 Dec 15 (Print Publication: 2014).