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Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
IntroductionExtracellular matrix (ECM) materials accumulate in the trabecular meshwork (TM) tissue of patients with glaucoma, which is associated with a decrease in aqueous humor outflow and therefore an increase in intraocular pressure. To explore a
Externí odkaz:
https://doaj.org/article/f6f4e6b211354820b70e9d608670b42a
Autor:
Alison E. Patteson, Haiyan Li, Nasim Annabi, Preethi S. Ganapathy, Tyler Bague, Alexander Kirschner, W. Daniel Stamer, Ana N. Strat, Samuel Herberg, Haven Roberts, Robert W. Weisenthal
PurposeAbnormal human trabecular meshwork (HTM) cell function and extracellular matrix (ECM) remodeling contribute to HTM stiffening in primary open-angle glaucoma (POAG). Most current cellular HTM model systems do not sufficiently replicate the comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7660e04e12bc26affc7247f0fb7795
https://doi.org/10.1101/2020.07.31.229229
https://doi.org/10.1101/2020.07.31.229229