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Autor:
Vanesa Alvarez, Susanne Bandau, Hao Jiang, Diana Rios-Szwed, Jens Hukelmann, Elisa Garcia-Wilson, Nicola Wiechens, Eva Griesser, Sara Ten Have, Tom Owen-Hughes, Angus Lamond, Constance Alabert
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111996- (2023)
Summary: Chromatin organization must be maintained during cell proliferation to preserve cellular identity and genome integrity. However, DNA replication results in transient displacement of DNA-bound proteins, and it is unclear how they regain acces
Externí odkaz:
https://doaj.org/article/1a042ff554f14fca972efa6c2e4f302b
Publikováno v:
Fly, Vol 14, Iss 1-4, Pp 10-28 (2020)
Quantitative proteomic analyses in combination with genetics provide powerful tools in developmental cell signalling research. Drosophila melanogaster is one of the most widely used genetic models for studying development and disease. Here we combine
Externí odkaz:
https://doaj.org/article/ed9f1781c79142c6bac0bb4f1cc889d9
Autor:
Elias, Martina S., Wright, Sheila C., Remenyi, Judit, Abbott, James C., Bray, Susan E., Cole, Christian, Edwards, Sharon, Gierlinski, Marek, Glok, Mateusz, McGrath, John A., Nicholson, William V., Paternoster, Lavinia, Prescott, Alan R., Have, Sara Ten, Whitfield, Phillip D., Lamond, Angus I., Brown, Sara J.
Publikováno v:
In The Journal of Allergy and Clinical Immunology August 2019 144(2):470-481
Autor:
A. Gregory Matera, Amanda C. Raimer, Casey A. Schmidt, Jo A. Kelly, Gaith N. Droby, David Baillat, Sara ten Have, Angus I. Lamond, Eric J. Wagner, Kelsey M. Gray
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 2, Pp 491-503 (2019)
Spinal Muscular Atrophy (SMA) is caused by homozygous mutations in the human survival motor neuron 1 (SMN1) gene. SMN protein has a well-characterized role in the biogenesis of small nuclear ribonucleoproteins (snRNPs), core components of the spliceo
Externí odkaz:
https://doaj.org/article/c52889db62ab45b8b93dc506e82567c4
Autor:
Martina S. Elias, Sheila C. Wright, William V. Nicholson, Kimberley D. Morrison, Alan R. Prescott, Sara Ten Have, Phillip D. Whitfield, Angus I. Lamond, Sara J. Brown
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Atopic eczema is an itchy inflammatory disorder characterised by skin barrier dysfunction. Loss-of-function mutations in the gene encoding filaggrin (FLG) are a major risk factor, but the mechanisms by which filaggrin haploinsufficiency l
Externí odkaz:
https://doaj.org/article/14616f7f675c4e30b80ba40a1401b765
Autor:
Martina S. Elias, Sheila C. Wright, William V. Nicholson, Kimberley D. Morrison, Alan R. Prescott, Sara Ten Have, Phillip D. Whitfield, Angus I. Lamond, Sara J. Brown
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Atopic eczema is an itchy inflammatory disorder characterised by skin barrier dysfunction. Loss-of-function mutations in the gene encoding filaggrin (FLG) are a major risk factor, but the mechanisms by which filaggrin haploinsufficiency l
Externí odkaz:
https://doaj.org/article/11969b6df6324a9fab1ed4098282a9b4
Autor:
Katharina Schleicher, Michael Porter, Sara ten Have, Ramasubramanian Sundaramoorthy, Iain M. Porter, Jason R. Swedlow
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Regulation of protein phosphatase activity by endogenous protein inhibitors is an important mechanism to control protein phosphorylation in cells. We recently identified Biorientation defective 1 (Bod1) as a small protein inhibitor of protein phospha
Externí odkaz:
https://doaj.org/article/afbcbb801cf14923a997a6fbdf777098
Publikováno v:
In Journal of Proteomics 2 August 2013 88:92-103