Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hava Glickstein"'
Autor:
Kumudesh Mishra, Sahar Sweetat, Saja Baraghithy, Uri Sprecher, Monzer Marisat, Sultan Bastu, Hava Glickstein, Joseph Tam, Hanna Rosenmann, Miguel Weil, Edoardo Malfatti, Or Kakhlon
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 893 (2024)
Glycogen storage disease type III (GSDIII) is a hereditary glycogenosis caused by deficiency of the glycogen debranching enzyme (GDE), an enzyme, encoded by Agl, enabling glycogen degradation by catalyzing alpha-1,4-oligosaccharide side chain transfe
Externí odkaz:
https://doaj.org/article/73e5be5b00194bf9b242473aca67c83c
Autor:
Meir Schechter, Jessica Grigoletto, Suaad Abd-Elhadi, Hava Glickstein, Alexander Friedman, Geidy E. Serrano, Thomas G. Beach, Ronit Sharon
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-21 (2020)
Abstract Background α-Synuclein (α-Syn) is a protein implicated in the pathogenesis of Parkinson’s disease (PD). α-Syn has been shown to associate with membranes and bind acidic phospholipids. However, the physiological importance of these assoc
Externí odkaz:
https://doaj.org/article/23d231e5775545c5a0206e97aa70d5ad
Publikováno v:
Blood. 106:3242-3250
The primary targets of iron chelators used for treating transfusional iron overload are prevention of iron ingress into tissues and its intracellular scavenging. The present study was aimed at elucidating the capacity of clinically important iron che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb71b8a1be0f1671415aace383ab85b
https://doi.org/10.1182/blood-2005-02-0460
https://doi.org/10.1182/blood-2005-02-0460
Autor:
Carole Beaumont, Virginie Picard, Z. Ioav Cabantchik, Hava Glickstein, Silvina Epsztejn, Itzchak Slotki, William Breuer
Publikováno v:
Blood. 94:3593-3603
The labile iron pool (LIP) of animal cells has been implicated in cell iron regulation and as a key component of the oxidative-stress response. A major mechanism commonly implied in the downregulation of LIP has been the induced expression of ferriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acd10e89a3c572caa8da1d2c6c4a28c2
https://doi.org/10.1182/blood.v94.10.3593.422k26_3593_3603
https://doi.org/10.1182/blood.v94.10.3593.422k26_3593_3603
Autor:
Abraham M. Konijn, Z. Ioav Cabantchik, Boris Vaisman, Hava Glickstein, Esther G. Meyron-Holtz, Itzchak Slotki
Publikováno v:
Blood. 94:2128-2134
The labile iron pool (LIP) harbors the metabolically active and regulatory forms of cellular iron. We assessed the role of intracellular ferritin in the maintenance of intracellular LIP levels. Treating K562 cells with the permeant chelator isonicoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdff0d54361e4906d7845d90c47cf1ba
https://doi.org/10.1182/blood.v94.6.2128.418k20_2128_2134
https://doi.org/10.1182/blood.v94.6.2128.418k20_2128_2134
Publikováno v:
Analytical Biochemistry. 248:31-40
The labile iron pool (LIP) of cells constitutes a cytosolic fraction of iron which is accessible to permeant chelators and contains the cells' metabolically and catalytically reactive iron. LIP is maintained by a balanced movement of iron from extra-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c22ced64ad61487e37db17f03e456a
https://doi.org/10.1006/abio.1997.2126
https://doi.org/10.1006/abio.1997.2126
Autor:
Or Kakhlon, Tatsuo Terashima, Hasan O. Akman, Otto Baba, Salvatore DiMauro, Naomi Feinstein, Yan Liu, Hava Glickstein, Alexander Lossos
Publikováno v:
Journal of neurochemistry. 127(1)
Uncontrolled elongation of glycogen chains, not adequately balanced by their branching, leads to the formation of an insoluble, presumably neurotoxic, form of glycogen called polyglucosan. To test the suspected pathogenicity of polyglucosans in neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38ad765c6af5df82a667c42ac20c695
https://pubmed.ncbi.nlm.nih.gov/23607684
https://pubmed.ncbi.nlm.nih.gov/23607684
Autor:
Abraham Shanzer, Zvi Ioav Cabantchik, Abraham M. Konijn, M Loyevsky, Hava Glickstein, William Breuer
Publikováno v:
Blood. 87:4871-4878
Iron chelators of the hydroxamate class arrest in vitro proliferation of malaria parasites end of mammalian cells. The factors determining the biological activity of the chelators have classically been attributed to the chelators' capacity for bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0216e2c93518c46af591272dce03df32
https://doi.org/10.1182/blood.v87.11.4871.bloodjournal87114871
https://doi.org/10.1182/blood.v87.11.4871.bloodjournal87114871
Autor:
Norbert Kartner, John R. Riordan, Hava Glickstein, William Breuer, Dennis A. Ausiello, Ioav Cabantchik
Publikováno v:
Journal of Biological Chemistry. 268:13935-13939
Expression of the cystic fibrosis transmembrane conductance regulator (CFTR) in epithelial cells is known to be down-regulated by the action of phorbol myristate acetate (PMA). We show here that in addition to suppressing the rate of transcription of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b19f67bb1c28e4ec314ac8eccec19cba
https://doi.org/10.1016/s0021-9258(19)85192-x
https://doi.org/10.1016/s0021-9258(19)85192-x
Autor:
Abraham M. Konijn, William Breuer, Rinat Ben El, Chaim Hershko, Hanspeter Nick, Gabi Link, Z. Ioav Cabantchik, Hava Glickstein
Publikováno v:
Blood. 108(9)
Labile iron in hemosiderotic plasma and tissue are sources of iron toxicity. We compared the iron chelators deferoxamine, deferiprone, and deferasirox as scavengers of labile iron in plasma and cardiomyocytes at therapeutic concentrations. This compr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6cce5f440f71f1d0ba7d0cc98b9062
https://pubmed.ncbi.nlm.nih.gov/16835377
https://pubmed.ncbi.nlm.nih.gov/16835377