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Unsupervised Classification of the Host Response Identifies Dominant Pathobiological Signatures of Sepsis in Sub-Saharan Africa.

Autor: Cummings MJ; Columbia University Medical Center, Division of Pulmonary, Allergy, and Critical Care Medicine , New York, New York, United States; mjc2244@columbia.edu., Lutwama JJ; Uganda Virus Research Institute, National Influenza Center, Entebbe, Uganda., Owor N; Uganda Virus Research Institute, National Influenza Center, Entebbe, Uganda., Tomoiaga AS; Manhattan College, Riverdale, New York, United States., Ross JE; Columbia University Medical Center, New York, New York, United States., Muwanga M; Entebbe General Hospital, Ministry of Health, Entebbe, Wakiso, Uganda., Nsereko C; Entebbe General Hospital, Entebbe, Wakiso, Uganda., Nayiga I; Entebbe General Hospital, Entebbe, Wakiso, Uganda., Kyebambe S; Entebbe General Hospital, Entebbe, Wakiso, Uganda., Shinyale J; Entebbe General Hospital, Ministry of Health, Entebbe, Wakiso, Uganda., Ochar T; Tororo General Hospital, Tororo, Uganda., Kiwubeyi M; Tororo General Hospital, Tororo, Uganda., Nankwanga R; Tororo General Hospital, Tororo, Uganda., Nie K; Icahn School of Medicine at Mount Sinai, New York, New York, United States., Xie H; Icahn School of Medicine at Mount Sinai, New York, New York, United States., Miake-Lye S; Icahn School of Medicine at Mount Sinai, New York, New York, United States., Villagomez B; Icahn School of Medicine at Mount Sinai, New York, New York, United States., Qi J; Icahn School of Medicine at Mount Sinai, New York, New York, United States., Reynolds SJ; National Institutes of Health, Laboratory of Immunoregulation, Bethesda, United States., Nakibuuka MC; Rakai Health Sciences Program, Kalisizo, Central Region, Uganda., Lu X; Columbia University Medical Center, New York, New York, United States., Kayiwa J; Uganda Virus Research Institute, National Influenza Center, Entebbe, Uganda., Haumba M; Uganda Virus Research Institute, National Influenza Center, Entebbe, Uganda., Nakaseegu J; Uganda Virus Research Institute, National Influenza Center, Entebbe, Uganda., Che X; Columbia University Mailman School of Public Health, New York, New York, United States., Wayengera M; Makerere University CHS, Kampala, Uganda., Ghosh S; Columbia University Vagelos College of Physicians and Surgeons, New York, New York, United States., Kim-Schulze S; Icahn School of Medicine at Mount Sinai, Human Immune Monitoring Center (HIMC), Hess Center for Science and Medicine, New York, New York, United States., Lipkin WI; Columbia University Mailman School of Public Health, New York, New York, United States., Bakamutumaho B; Uganda Virus Research Institute, National Influenza Center, Entebbe, Uganda., O'Donnell MR; Columbia University Medical Center, Department of Medicine, New York, New York, United States.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Nov 08. Date of Electronic Publication: 2024 Nov 08.