Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Haukur Gudnason"'
Publikováno v:
BioTechniques, Vol 45, Iss 3, Pp 261-271 (2008)
Microarrays printed on glass slides are often constructed by covalently linking modified oligonucleotide probes to a derivatized surface at considerable expense. In this article, we demonstrate that 14-base oligonucleotides with a poly(T)10 – poly(
Externí odkaz:
https://doaj.org/article/f60117e9a10645f5a411a7bf3f4e547f
Autor:
Bjorn T Adalsteinsson, Haukur Gudnason, Thor Aspelund, Tamara B Harris, Lenore J Launer, Gudny Eiriksdottir, Albert V Smith, Vilmundur Gudnason
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46705 (2012)
Epigenetic studies are commonly conducted on DNA from tissue samples. However, tissues are ensembles of cells that may each have their own epigenetic profile, and therefore inter-individual cellular heterogeneity may compromise these studies. Here, w
Externí odkaz:
https://doaj.org/article/152a7e4549d049cbb5873d94b6fb4478
Autor:
Julie A. Marsh, Meike W. Vernooij, Nicholas J. Timpson, Linda S. Adair, Maksim Struchalin, Kelly S. Benke, Alex P. Zijdenbos, Wiro J. Niessen, Dexter Hadley, André Scherag, Niina Siitonen, Johannes Hedebrand, Helena Schmidt, Iona Y. Millwood, Emily Oken, David S. Knopman, James F. Wilson, H. Rob Taal, Henri A. Vrooman, Karen L. Mohlke, Myriam Fornage, Vilmundur Gudnason, Leslie A. Lange, Sigurdur Sigurdsson, Maria M. Groen-Blokhuis, Diane J. Catellier, Stefan Ropele, Seang Mei Saw, Sylvain Sebert, Alexa S. Beiser, Lyle J. Palmer, Claudia Flexeder, Paul Elliott, George Davey Smith, John W. Holloway, Michel G. Nivard, Mike A. Nalls, Albert V. Smith, Cyrus Cooper, E Zeggini, Terho Lehtimäki, Struan F.A. Grant, Virpi Lindi, Romy Gaillard, B. Gwen Windham, Dennis O. Mook-Kanamori, Claus Holst, Timo A. Lakka, Stéphanie Debette, Liang Kee Goh, Ewan R. Pearson, Tamara B. Harris, Momoko Horikoshi, Jeffrey C. Murray, Mirna Kirin, M. Arfan Ikram, George V. Dedoussis, Anita L. DeStefano, Clifford R. Jack, Alex Lewin, Reedik Maggi, Vincent W. V. Jaddoe, Haukur Gudnason, Hakon Hakonarson, Thomas H. Mosley, Alina Rodriguez, Sudha Seshadri, William M. Meeks, Philip A. Wolf, Gonneke Willemsen, B. Valcarcel, Anke Hinney, Eric A.P. Steegers, Lenore J. Launer, Elina Hyppönen, Lachlan J. M. Coin, Elisabeth Thiering, Mustafa Atalay, W. T. Longstreth, Thorkild I. A. Sørensen, André G. Uitterlinden, Christel M. Middeldorp, Matthew W. Gillman, Ken K. Ong, Oliver S. P. Davis, Monique M.B. Breteler, Wei Ang, Ulla Sovio, Tuomas O. Kilpeläinen, Ioanna Ntalla, Marjo-Riitta Järvelin, Aad van der Lugt, Cornelia M. van Duijn, Cecilia M. Lindgren, Rany M. Salem, Laura H. Coker, Craig E. Pennell, Fernando Rivadeneira, Thomas S. Price, Charles DeCarli, Dorret I. Boomsma, Ellen Aagaard Nohr, Diane Berry, Rhoda Au, Yik Y. Teo, Ville Huikari, Jouke-Jan Hottenga, Matthew Kowgier, Joachim Heinrich, Nienke E. Bergen, Beate St Pourcain, Reinhold Schmidt, C Power, Kalliope Panoutsopoulou, Olli T. Raitakari, Albert Hofman, Mark I. McCarthy, Joel N. Hirschhorn, Olli Simell, Claire M. A. Haworth, Mark A. van Buchem, Anna-Liisa Hartikainen, Berthold Hocher, Debbie A Lawlor, Jennifer Pararajasingham, Toos C. E. M. van Beijsterveldt, David P. Strachan, Hanna Maaria Lakka, Timothy M. Frayling
Publikováno v:
Nature Genetics
Nature Genetics, 44(5), 539
Ikram, M A, Fornage, M, Smith, A V, Seshadri, S, Schmidt, R, Debette, S, Vrooman, H A, Sigurdsson, S, Ropele, S, Taal, H R, Mook-Kanamori, D O, Coker, L H, Longstreth, W T, Niessen, W J, DeStefano, A L, Beiser, A, Zijdenbos, A P, Struchalin, M, Jack, C R, Rivadeneira, F, Uitterlinden, A G, Knopman, D S, Hartikainen, A-L, Pennell, C E, Thiering, E, Steegers, E A P, Hakonarson, H, Heinrich, J, Palmer, L J, Jarvelin, M-R, McCarthy, M I, Grant, S F A, St Pourcain, B, Timpson, N J, Smith, G D, Sovio, U, Nalls, M A, Au, R, Hofman, A, Gudnason, H, van der Lugt, A, Harris, T B, Meeks, W M, Vernooij, M W, van Buchem, M A, Catellier, D, Jaddoe, V W V, Gudnason, V & Windham, B G & Wilson, J F 2012, ' Common variants at 6q22 and 17q21 are associated with intracranial volume ', Nature Genetics, vol. 44, no. 5, pp. 539-+ . https://doi.org/10.1038/ng.2245
Nature Genetics, 44(5), 539-544. Nature Publishing Group
Nature Genetics; Vol 44
Nature Genetics, 44(5), 539-+. Nature Publishing Group
Arfan Ikram, M, Fornage, M, Smith, A V, Seshadri, S, Schmidt, R, Debette, S, Vrooman, H A, Sigurdsson, S, Ropele, S, Taal, H R, Mook-Kanamori, D O, Coker, L H, Longstreth, J W T, Niessen, W J, DeStefano, A L, Beiser, A, Zijdenbos, A P, Struchalin, M, Jack, C R, Rivadeneira, F, Uitterlinden, A G, Knopman, D S, Hartikainen, A-L, Pennell, C E, Thiering, E, Steegers, E A P, Hakonarson, H, Heinrich, J, Palmer, L J, Jarvelin, M-R, McCarthy, M I, Grant, S F A, St Pourcain, B, Timpson, N J, Smith, G D, Sovio, U, van Beijsterveldt, C E M, Groen-Blokhuis, M M, Hottenga, J J, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, Nalls, M A, Au, R, Hofman, A, Gudnason, H, van der Lugt, A, Harris, T B, Meeks, W M, Vernooij, M W, van Buchem, M A, Catellier, D, Jaddoe, V W V, Gudnason, V, Windham, B G, Wolf, P A, van Duijn, C M, Mosley, T H, Schmidt, H, Launer, L J, Breteler, M M B & DeCarli, C S 2012, ' Common variants at 6q22 and 17q21 are associated with intracranial volume ', Nature Genetics, vol. 44, no. 5, pp. 539-544 . https://doi.org/10.1038/ng.2245
Nature genetics 44(5), 539-544 (2012). doi:10.1038/ng.2245
Nature Genetics, 44(5), 539
Ikram, M A, Fornage, M, Smith, A V, Seshadri, S, Schmidt, R, Debette, S, Vrooman, H A, Sigurdsson, S, Ropele, S, Taal, H R, Mook-Kanamori, D O, Coker, L H, Longstreth, W T, Niessen, W J, DeStefano, A L, Beiser, A, Zijdenbos, A P, Struchalin, M, Jack, C R, Rivadeneira, F, Uitterlinden, A G, Knopman, D S, Hartikainen, A-L, Pennell, C E, Thiering, E, Steegers, E A P, Hakonarson, H, Heinrich, J, Palmer, L J, Jarvelin, M-R, McCarthy, M I, Grant, S F A, St Pourcain, B, Timpson, N J, Smith, G D, Sovio, U, Nalls, M A, Au, R, Hofman, A, Gudnason, H, van der Lugt, A, Harris, T B, Meeks, W M, Vernooij, M W, van Buchem, M A, Catellier, D, Jaddoe, V W V, Gudnason, V & Windham, B G & Wilson, J F 2012, ' Common variants at 6q22 and 17q21 are associated with intracranial volume ', Nature Genetics, vol. 44, no. 5, pp. 539-+ . https://doi.org/10.1038/ng.2245
Nature Genetics, 44(5), 539-544. Nature Publishing Group
Nature Genetics; Vol 44
Nature Genetics, 44(5), 539-+. Nature Publishing Group
Arfan Ikram, M, Fornage, M, Smith, A V, Seshadri, S, Schmidt, R, Debette, S, Vrooman, H A, Sigurdsson, S, Ropele, S, Taal, H R, Mook-Kanamori, D O, Coker, L H, Longstreth, J W T, Niessen, W J, DeStefano, A L, Beiser, A, Zijdenbos, A P, Struchalin, M, Jack, C R, Rivadeneira, F, Uitterlinden, A G, Knopman, D S, Hartikainen, A-L, Pennell, C E, Thiering, E, Steegers, E A P, Hakonarson, H, Heinrich, J, Palmer, L J, Jarvelin, M-R, McCarthy, M I, Grant, S F A, St Pourcain, B, Timpson, N J, Smith, G D, Sovio, U, van Beijsterveldt, C E M, Groen-Blokhuis, M M, Hottenga, J J, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, Nalls, M A, Au, R, Hofman, A, Gudnason, H, van der Lugt, A, Harris, T B, Meeks, W M, Vernooij, M W, van Buchem, M A, Catellier, D, Jaddoe, V W V, Gudnason, V, Windham, B G, Wolf, P A, van Duijn, C M, Mosley, T H, Schmidt, H, Launer, L J, Breteler, M M B & DeCarli, C S 2012, ' Common variants at 6q22 and 17q21 are associated with intracranial volume ', Nature Genetics, vol. 44, no. 5, pp. 539-544 . https://doi.org/10.1038/ng.2245
Nature genetics 44(5), 539-544 (2012). doi:10.1038/ng.2245
During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect differ
Publikováno v:
BioTechniques. 45:261-271
Microarrays printed on glass slides are often constructed by covalently linking modified oligonucleotide probes to a derivatized surface at considerable expense. In this article, we demonstrate that 14-base oligonucleotides with a poly(T)10 – poly(
Publikováno v:
International journal of oncology. 45(4)
Colorectal cancer (CRC) is one of the most prevalent types of cancer, causing significant morbidity and mortality worldwide. CRC is curable if diagnosed at an early stage. Mutations in the oncogene KRAS play a critical role in early development of CR
Autor:
Jose R. Romero, Nicole L. Glazer, Jerome I. Rotter, Alex P. Zijdenbos, Thomas H. Mosley, Melissa Garcia, André G. Uitterlinden, Joshua C. Bis, Christophe Tzourio, M. Arfan Ikram, Tamara B. Harris, Thomas Lumley, Wiro J. Niessen, Jean-Charles Lambert, Philippe Amouyel, Bernard Mazoyer, Larry D. Atwood, Monique M.B. Breteler, Henri A. Vrooman, Sigurdur Sigurdsson, Meike W. Vernooij, Susan R. Heckbert, Albert Hofman, Philip A. Wolf, Carole Dufouil, Katja Petrovic, Lenore J. Launer, Pauline Maillard, Alexa S. Beiser, Diane J. Catellier, Richey Sharrett, Anita L. DeStefano, Mary Cushman, Haukur Gudnason, Mike A. Nalls, Margherita Cavalieri, Stéphanie Debette, Sudha Seshadri, Vilmundur Gudnason, Oscar L. Lopez, Albert V. Smith, Franz Fazekas, Eric Boerwinkle, Aad van der Lugt, Cornelia M. van Duijn, Qiong Yang, Myriam Fornage, Kenneth Rice, Renske de Boer, W. T. Longstreth, David S. Knopman, Reinhold Schmidt, Charles DeCarli, Gerardo Heiss, Rebecca F. Gottesman, Thor Aspelund, Rhoda Au, Nicholas L. Smith, Dean Shibata, Helena Schmidt, Kent D. Taylor, Christian Enzinger, Bruce M. Psaty
Publikováno v:
Annals of Neurology, 69(6), 928-939. John Wiley & Sons Inc.
Annals of Neurology
Annals of Neurology, Wiley, 2011, 69, pp.928-939. ⟨10.1002/ana.22403⟩
Annals of Neurology, 2011, 69, pp.928-939. ⟨10.1002/ana.22403⟩
Annals of Neurology
Annals of Neurology, Wiley, 2011, 69, pp.928-939. ⟨10.1002/ana.22403⟩
Annals of Neurology, 2011, 69, pp.928-939. ⟨10.1002/ana.22403⟩
International audience; OBJECTIVE: White matter hyperintensities (WMHs) detectable by magnetic resonance imaging are part of the spectrum of vascular injury associated with aging of the brain and are thought to reflect ischemic damage to the small de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4c009a2e9bcb217493c0c623408134
https://pure.eur.nl/en/publications/6323a574-e21c-4048-a6fc-6dfdd44f6d17
https://pure.eur.nl/en/publications/6323a574-e21c-4048-a6fc-6dfdd44f6d17
Autor:
Tamara B. Harris, Bjorn T. Adalsteinsson, Lenore J. Launer, Vilmundur Gudnason, Thor Aspelund, Gudny Eiriksdottir, Haukur Gudnason, Albert V. Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46705 (2012)
PLoS ONE
PLoS ONE
Epigenetic studies are commonly conducted on DNA from tissue samples. However, tissues are ensembles of cells that may each have their own epigenetic profile, and therefore inter-individual cellular heterogeneity may compromise these studies. Here, w
Autor:
Craig E. Pennell, Henri A. Vrooman, Beate St Pourcain, Albert V. Smith, Clifford R. Jack, Monique M.B. Breteler, Alex P. Zijdenbos, André G. Uitterlinden, Charles DeCarli, Nicholas J. Timpson, David S. Knopman, Sudha Seshadri, Wiro J. Niessen, Mark A. van Buchem, Rhoda Au, Vilmundur Gudnason, Ulla Sovio, Aad van der Lugt, Laura H. Coker, Cornelia M. van Duijn, Hakon Hakonarson, Marjo-Riitta Järvelin, Maksim Struchalin, W. T. Longstreth, Stefan Ropele, Albert Hofman, H. Rob Taal, George Davey Smith, Tamara B. Harris, Elisabeth Thiering, Mark I. McCarthy, Stéphanie Debette, Myriam Fornage, Alexa S. Beiser, Joachim Heinrich, Meike W. Vernooij, Anna-Liisa Hartikainen, Lyle J. Palmer, B. Gwen Windham, Mike A. Nalls, Dennis O. Mook-Kanamori, Thomas H. Mosley, Vincent W. V. Jaddoe, Lenore J. Launer, Philip A. Wolf, Sigurdur Sigurdsson, Helena Schmidt, Fernando Rivadeneira, M. Arfan Ikram, Anita L. DeStefano, Haukur Gudnason, William M. Meeks, Reinhold E. Schmidt, Eric A.P. Steegers, Struan F.A. Grant, Diane J. Catellier
Publikováno v:
Nature Genetics. 44:732-732
Publikováno v:
Nucleic Acids Research
The importance of real-time polymerase chain reaction (PCR) has increased steadily in clinical applications over the last decade. Many applications utilize SYBR Green I dye to follow the accumulation of amplicons in real time. SYBR Green I has, howev
Publikováno v:
Technical University of Denmark Orbit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7fb65f9515c4506c509a33e723484d9f
https://orbit.dtu.dk/en/publications/23aad68f-efba-49ad-8736-736f66dc1ded
https://orbit.dtu.dk/en/publications/23aad68f-efba-49ad-8736-736f66dc1ded