Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hauke Holthusen"'
Autor:
Itika Saha, Patricia Yuste-Checa, Miguel Da Silva Padilha, Qiang Guo, Roman Körner, Hauke Holthusen, Victoria A. Trinkaus, Irina Dudanova, Rubén Fernández-Busnadiego, Wolfgang Baumeister, David W. Sanders, Saurabh Gautam, Marc I. Diamond, F. Ulrich Hartl, Mark S. Hipp
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Tau aggregates are associated with several neurodegenerative disorders. In this work, I. Saha and colleagues show that valosin-containing protein (VCP) recruited to Tau fibrils disaggregates them. However, this process comes at a cost: it generates s
Externí odkaz:
https://doaj.org/article/55b4a135031e4d249c4f455de3857bf8
Autor:
Itika Saha, Patricia Yuste-Checa, Miguel Da Silva Padilha, Qiang Guo, Roman Körner, Hauke Holthusen, Victoria A. Trinkaus, Irina Dudanova, Rubén Fernández-Busnadiego, Wolfgang Baumeister, David W. Sanders, Saurabh Gautam, Marc I. Diamond, F. Ulrich Hartl, Mark S. Hipp
Amyloid-like aggregates of the microtubule-associated protein Tau are associated with several neurodegenerative disorders including Alzheimer’s disease. The existence of cellular machinery for the removal of such aggregates has remained unclear, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::377a11ac3ba13792fcb8ab108b3e97aa
https://doi.org/10.1101/2022.02.18.481043
https://doi.org/10.1101/2022.02.18.481043
Autor:
Ritwick Sawarkar, Mark S. Hipp, Jenny Presto, F. Ulrich Hartl, Lisa Vincenz-Donnelly, Hauke Holthusen, Jan Johansson, Erik C Hansen, Roman Körner
Publikováno v:
The EMBO Journal
Protein aggregation is associated with neurodegeneration and various other pathologies. How specific cellular environments modulate the aggregation of disease proteins is not well understood. Here, we investigated how the endoplasmic reticulum (ER) q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bc70bf5b8f3522a23674fa50df7eb5
https://hdl.handle.net/21.11116/0000-0000-AF13-621.11116/0000-0000-AF15-4
https://hdl.handle.net/21.11116/0000-0000-AF13-621.11116/0000-0000-AF15-4