Subcellular NAD ⁺ pools are interconnected and buffered by mitochondrial NAD ^.

Autor: Høyland LE; Department of Biomedicine, University of Bergen, Bergen, Norway., VanLinden MR; Department of Biomedicine, University of Bergen, Bergen, Norway., Niere M; Department of Biomedicine, University of Bergen, Bergen, Norway., Strømland Ø; Department of Biomedicine, University of Bergen, Bergen, Norway., Sharma S; Department of Biomedicine, University of Bergen, Bergen, Norway.; Neuro-SysMed Center, Department of Neurology, Haukeland University Hospital, Bergen, Norway., Dietze J; Department of Arctic and Marine Biology, UiT The Arctic University of Norway, Tromsø, Norway., Tolås I; Department of Biomedicine, University of Bergen, Bergen, Norway.; Department of Biological Sciences, NTNU Ålesund, Ålesund, Norway., Lucena E; Department of Biomedicine, University of Bergen, Bergen, Norway., Bifulco E; Department of Biomedicine, University of Bergen, Bergen, Norway.; Department of Biological Sciences, University of Bergen, Bergen, Norway., Sverkeli LJ; Department of Biomedicine, University of Bergen, Bergen, Norway.; Department of Biological Sciences, University of Bergen, Bergen, Norway., Cimadamore-Werthein C; Department of Biomedicine, University of Bergen, Bergen, Norway.; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Ashrafi H; Department of Biomedicine, University of Bergen, Bergen, Norway., Haukanes KF; Department of Biomedicine, University of Bergen, Bergen, Norway., van der Hoeven B; Department of Biomedicine, University of Bergen, Bergen, Norway., Dölle C; Neuro-SysMed Center, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Bergen, Norway.; K.G. Jebsen Center for Translational Research in Parkinson's Disease, University of Bergen, Bergen, Norway., Davidsen C; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway., Pettersen IKN; Department of Biomedicine, University of Bergen, Bergen, Norway., Tronstad KJ; Department of Biomedicine, University of Bergen, Bergen, Norway., Mjøs SA; Department of Chemistry, University of Bergen, Bergen, Norway., Hayat F; Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA., Makarov MV; Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA., Migaud ME; Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA., Heiland I; Neuro-SysMed Center, Department of Neurology, Haukeland University Hospital, Bergen, Norway.; Department of Arctic and Marine Biology, UiT The Arctic University of Norway, Tromsø, Norway., Ziegler M; Department of Biomedicine, University of Bergen, Bergen, Norway. Mathias.Ziegler@uib.no.

Publikováno v: Nature metabolism [Nat Metab] 2024 Dec; Vol. 6 (12), pp. 2319-2337. Date of Electronic Publication: 2024 Dec 13.