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Defect-Engineered Metal-Organic Frameworks as Nanocarriers for Pharmacotherapy: Insights into Intracellular Dynamics at The Single Particle Level.

Autor: Huang G; Department of Chemistry & Nano-Science Center, Copenhagen University, Thorvaldsensvej 40, Frederiksberg, Copenhagen, 1871, Denmark.; Center for 4D Cellular Dynamics, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Center for Optimised Oligo Escape and Control of Disease, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark., Dreisler MW; Department of Chemistry & Nano-Science Center, Copenhagen University, Thorvaldsensvej 40, Frederiksberg, Copenhagen, 1871, Denmark.; Center for 4D Cellular Dynamics, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Center for Optimised Oligo Escape and Control of Disease, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark., Kæstel-Hansen J; Department of Chemistry & Nano-Science Center, Copenhagen University, Thorvaldsensvej 40, Frederiksberg, Copenhagen, 1871, Denmark.; Center for 4D Cellular Dynamics, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Center for Optimised Oligo Escape and Control of Disease, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark., Nielsen AJ; Department of Chemistry & Nano-Science Center, Copenhagen University, Thorvaldsensvej 40, Frederiksberg, Copenhagen, 1871, Denmark.; Center for 4D Cellular Dynamics, University of Copenhagen, Copenhagen, 2000, Denmark.; Department of Biology, Structural Biology and NMR Laboratory and the Linderstrøm-Lang Centre for Protein Science, University of Copenhagen, Copenhagen, 2200, Denmark., Zhang M; Department of Chemistry & Nano-Science Center, Copenhagen University, Thorvaldsensvej 40, Frederiksberg, Copenhagen, 1871, Denmark.; Center for 4D Cellular Dynamics, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Center for Optimised Oligo Escape and Control of Disease, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark., Hatzakis NS; Department of Chemistry & Nano-Science Center, Copenhagen University, Thorvaldsensvej 40, Frederiksberg, Copenhagen, 1871, Denmark.; Center for 4D Cellular Dynamics, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Center for Optimised Oligo Escape and Control of Disease, University of Copenhagen, Copenhagen, 2000, Denmark.; Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Aug; Vol. 36 (35), pp. e2405898. Date of Electronic Publication: 2024 Jul 10.

Reply to: On the statistical foundation of a recent single molecule FRET benchmark.

Autor: Götz M; PicoQuant GmbH, Rudower Chaussee 29, 12489, Berlin, Germany. goetz@picoquant.com., Barth A; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Van der Maasweg 9, 2629, HZ Delft, The Netherlands., Bohr SS; Department of Chemistry, University of Copenhagen, 2100, Copenhagen, Denmark.; Novo Nordisk Center for optimised oligo escape and control of disease University of Copenhagen, 2100 Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2100, Copenhagen, Denmark., Börner R; Department of Chemistry, University of Zurich, 8057, Zurich, Switzerland.; Laserinstitut Hochschule Mittweida, University of Applied Sciences Mittweida, 09648, Mittweida, Germany., Chen J; Department of Chemistry and Biochemistry, Ohio University, Athens, OH, USA., Cordes T; Physical and Synthetic Biology, Faculty of Biology, Ludwig-Maximilians-Universität München, Großhadernerstr. 2-4, 82152, Planegg-Martinsried, Germany., Erie DA; Department of Chemistry, University of North Carolina, Chapel Hill, NC, 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 27599, USA., Gebhardt C; Physical and Synthetic Biology, Faculty of Biology, Ludwig-Maximilians-Universität München, Großhadernerstr. 2-4, 82152, Planegg-Martinsried, Germany., Hadzic MCAS; Department of Chemistry, University of Zurich, 8057, Zurich, Switzerland., Hamilton GL; Department of Physics and Astronomy, Clemson University, Clemson, SC, 29634, USA.; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA., Hatzakis NS; Department of Chemistry, University of Copenhagen, 2100, Copenhagen, Denmark.; Novo Nordisk Center for optimised oligo escape and control of disease University of Copenhagen, 2100 Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2100, Copenhagen, Denmark., Hugel T; Institute of Physical Chemistry, University of Freiburg, Freiburg, Germany.; Signalling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Kisley L; Department of Physics, Case Western Reserve University, Cleveland, OH, USA.; Department of Chemistry, Case Western Reserve University, Cleveland, OH, USA., Lamb DC; Department of Chemistry and Center for Nano Science (CeNS), Ludwig Maximilians-Universität München, Butenandtstraße 5-13, 81377, München, Germany., de Lannoy C; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708PB, Wageningen, The Netherlands., Mahn C; Department of Physics, North Carolina State University, Raleigh, NC, 27695, USA., Dunukara D; Department of Physics, Case Western Reserve University, Cleveland, OH, USA., de Ridder D; Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708PB, Wageningen, The Netherlands., Sanabria H; Department of Physics and Astronomy, Clemson University, Clemson, SC, 29634, USA., Schimpf J; Institute of Physical Chemistry, University of Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany., Seidel CAM; Institut für Physikalische Chemie, Lehrstuhl für Molekulare Physikalische Chemie, Heinrich-Heine-Universität, Universitätsstr. 1, 40225, Düsseldorf, Germany., Sigel RKO; Department of Chemistry, University of Zurich, 8057, Zurich, Switzerland., Sletfjerding MB; Department of Chemistry, University of Copenhagen, 2100, Copenhagen, Denmark.; Novo Nordisk Center for optimised oligo escape and control of disease University of Copenhagen, 2100 Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2100, Copenhagen, Denmark., Thomsen J; Department of Chemistry, University of Copenhagen, 2100, Copenhagen, Denmark.; Novo Nordisk Center for optimised oligo escape and control of disease University of Copenhagen, 2100 Novo Nordisk Foundation Centre for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2100, Copenhagen, Denmark., Vollmar L; Institute of Physical Chemistry, University of Freiburg, Freiburg, Germany.; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany., Wanninger S; Department of Chemistry and Center for Nano Science (CeNS), Ludwig Maximilians-Universität München, Butenandtstraße 5-13, 81377, München, Germany., Weninger KR; Department of Physics, North Carolina State University, Raleigh, NC, 27695, USA., Xu P; Department of Physics, North Carolina State University, Raleigh, NC, 27695, USA., Schmid S; NanoDynamicsLab, Laboratory of Biophysics, Wageningen University, Stippeneng 4, 6708WE, Wageningen, The Netherlands. schmid@nanodynlab.org.; Department of Chemistry, University of Basel, Basel, Switzerland. schmid@nanodynlab.org.

Publikováno v: Nature communications [Nat Commun] 2024 Apr 30; Vol. 15 (1), pp. 3626. Date of Electronic Publication: 2024 Apr 30.