CSF1R inhibition depletes brain macrophages and reduces brain virus burden in SIV-infected macaques.

Autor: Bohannon DG; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA., Zablocki-Thomas LD; Department of Anatomy, Physiology & Cell Biology, University California, Davis School of Veterinary Medicine, Davis, CA 95616, USA., Leung ES; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA., Dupont JK; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA., Hattler JB; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA., Kowalewska J; Department of Pathology and Anatomy, Eastern Virginia Medical School, Norfolk, VA 23507, USA., Zhao M; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA., Luo J; Department of Health Systems and Population Health Sciences, the Tilman J. Fertitta Family College of Medicine, University of Houston, Houston, TX 77204, USA., Salemi M; Department of Epidemiology, University of Florida College of Medicine, Gainesville, FL 32610, USA., Amedee AM; Department of Microbiology, Immunology & Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA., Li Q; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA., Kuroda MJ; Department of Anatomy, Physiology & Cell Biology, University California, Davis School of Veterinary Medicine, Davis, CA 95616, USA., Kim WK; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA 23507, USA.; Division of Microbiology, Tulane National Primate Research Center, Covington, LA, 70433, USA.; Department of Microbiology & Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Publikováno v: Brain : a journal of neurology [Brain] 2024 Sep 03; Vol. 147 (9), pp. 3059-3069.

Development of Droplet Digital PCR-Based Assays to Quantify HIV Proviral and Integrated DNA in Brain Tissues from Viremic Individuals with Encephalitis and Virally Suppressed Aviremic Individuals.

Autor: Chung HK; Advanced BioScience Laboratories, Inc., Rockville, Maryland, USA., Hattler JB; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical Schoolgrid.255414.3, Norfolk, Virginia, USA., Narola J; Advanced BioScience Laboratories, Inc., Rockville, Maryland, USA., Babbar H; Advanced BioScience Laboratories, Inc., Rockville, Maryland, USA., Cai Y; The Wistar Institute, Philadelphia, Pennsylvania, USA., Abdel-Mohsen M; The Wistar Institute, Philadelphia, Pennsylvania, USA., Kim WK; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical Schoolgrid.255414.3, Norfolk, Virginia, USA.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2022 Feb 23; Vol. 10 (1), pp. e0085321. Date of Electronic Publication: 2022 Jan 12.

Perivascular macrophages in the neonatal macaque brain undergo massive necroptosis after simian immunodeficiency virus infection.

Autor: Bohannon DG; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA., Wang Y; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA., Reinhart CH; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA., Hattler JB; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA., Luo J; EVMS-Sentara Healthcare Analytics and Delivery Science Institute, Eastern Virginia Medical School, Norfolk, VA., Okhravi HR; Glennan Center for Geriatrics and Gerontology, Eastern Virginia Medical School, Norfolk, VA., Zhang J; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE., Li Q; Nebraska Center for Virology, School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, NE., Kuroda MJ; Center for Comparative Medicine, University of California, Davis, Davis, CA., Kim J; Cedars-Sinai Medical Center, University of California, Los Angeles, Los Angeles, CA., Kim WK; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA.

Publikováno v: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2020 May; Vol. 30 (3), pp. 603-613. Date of Electronic Publication: 2019 Dec 26.

Lentiviral infection of proliferating brain macrophages in HIV and simian immunodeficiency virus encephalitis despite sterile alpha motif and histidine-aspartate domain-containing protein 1 expression.

Autor: Lindgren AA; Department of Microbiology and Molecular Cell Biology., Filipowicz AR; Department of Microbiology and Molecular Cell Biology., Hattler JB; Department of Microbiology and Molecular Cell Biology., Kim SO; Department of Physiological Sciences, Eastern Virginia Medical School, Norfolk, Virginia., Chung HK; Department of Innovation and Translation, Advanced BioScience Laboratories, Inc, Rockville, Maryland., Kuroda MJ; Division of Immunology, Tulane National Primate Research Center, Covington, Louisiana, USA., Johnson EM; Department of Microbiology and Molecular Cell Biology., Kim WK; Department of Microbiology and Molecular Cell Biology.

Publikováno v: AIDS (London, England) [AIDS] 2018 May 15; Vol. 32 (8), pp. 965-974.