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pro vyhledávání: '"Hatsune Segawa"'
Autor:
Hatsune Segawa, Kohji Noguchi, Noritaka Tanaka, Kazuhiro Katayama, Yuri Masuda, Yoshikazu Sugimoto, Junko Mitsuhashi
Publikováno v:
Biochemical and Biophysical Research Communications. 415:305-312
Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) is associated with malignancy. KSHV-derived vFLIP is structurally related to cellular FLIP and binds to NEMO/IκB kinase (IKKγ) to activate NF-κB signaling. NF-κB activation is postulated to con