Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hatim M. Mustaly"'
Autor:
Sanghee Lim, Nicole Hermance, Tenny Mudianto, Hatim M. Mustaly, Ian Paolo Morelos Mauricio, Marc A. Vittoria, Ryan J. Quinton, Brian W. Howell, Hauke Cornils, Amity L. Manning, Neil J. Ganem
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Hippo pathway inactivation plays a role in many cancers, although how tumor cells depress signaling is unclear. Here, Lim et al. identify STK25, which activates LATS in a manner distinct from other upstream kinases and is focally deleted from a range
Externí odkaz:
https://doaj.org/article/fb44cfbe9f3a4df592b8189461124a06
Autor:
Marc A. Vittoria, Neil J. Ganem, Ryan J. Quinton, Hatim M. Mustaly, Hauke Cornils, Tenny Mudianto, Ian Paolo Morelos Mauricio, Nicole M. Hermance, Sanghee Lim, Brian W. Howell, Amity L. Manning
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
The Hippo pathway maintains tissue homeostasis by negatively regulating the oncogenic transcriptional co-activators YAP and TAZ. Though functional inactivation of the Hippo pathway is common in tumors, mutations in core pathway components are rare. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c33848e7dd64dbe81a90de2ee11b843
http://link.springer.com/article/10.1038/s41467-019-09597-w
http://link.springer.com/article/10.1038/s41467-019-09597-w
Autor:
Ryan J. Quinton, Sanghee Lim, Marc A. Vittoria, Neil J. Ganem, Ian Paolo Morelos Mauricio, Hatim M. Mustaly, Nicole M. Hermance, Hauke Cornils, Brian W. Howell, Tenny Mudianto, Amity L. Manning
The Hippo pathway maintains tissue homeostasis by negatively regulating the oncogenic transcriptional co-activators YAP and TAZ. Though functional inactivation of the Hippo pathway is common in tumors, mutations in core pathway components are rare. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3fc61ad96a062c107bbd516ecbf0c7
https://doi.org/10.1101/354233
https://doi.org/10.1101/354233
Autor:
Neil J. Ganem, Hatim M. Mustaly
Publikováno v:
eLS
Mammalian cells are charged with the task of evenly distributing 46 chromosomes to each of two daughter cells during every mitotic cell division. This is achieved by a microtubule-based cellular structure termed the mitotic spindle. However, numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6757e9f54ea8172bba51c7c278d893e4
https://doi.org/10.1002/9780470015902.a0005774.pub2
https://doi.org/10.1002/9780470015902.a0005774.pub2
Publikováno v:
Carpal Tunnel Syndrome and Related Median Neuropathies ISBN: 9783319570082
This chapter discusses the pathophysiological mechanisms and contributing factors underlying the etiology of carpal tunnel syndrome. The etiology of carpal tunnel syndrome is complex and still has not been fully elucidated. Many factors have been imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adde828dbf0343287193f9276b72d976
https://doi.org/10.1007/978-3-319-57010-5_3
https://doi.org/10.1007/978-3-319-57010-5_3