Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hatem M, Gaber"'
Autor:
Mai A. Mansour, Mamdouh A. Oraby, Zeinab A. Muhammad, Deena S. Lasheen, Hatem M. Gaber, Khaled A. M. Abouzid
Publikováno v:
RSC Advances. 12:8193-8201
Various substituted synthetic chalcones demonstrated potent anti-cancer activities.
Autor:
Mahgoub M Ahmed, Sobhi M. Gomha, Hatem M. Gaber, Zeinab A. Muhammad, Eman A. Taher, Hesham R. El-Seedi, Abdelwahed R. Sayed
Publikováno v:
Drug Design, Development and Therapy. 14:1363-1375
Background Thiazole and thiosemicarbazone derivatives are known to have potential anticancer activity with a mechanism of action related to inhibition of matrix metallo-proteinases, kinases and anti-apoptotic BCL2 family proteins. Materials and metho
Publikováno v:
Molecules, Vol 8, Iss 11, Pp 793-865 (2003)
The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alk
Externí odkaz:
https://doaj.org/article/c6f71d9a0afe4d3786c24d8804f769bc
Autor:
Hatem M. Gaber, Sami S. Ghabrial
Publikováno v:
Molecules, Vol 8, Iss 5, Pp 401-410 (2003)
The novel 2-aryl-3a,4,12,12a-tetrahydropyrrolo[3',4':4,3]-pyridazino[6,1-b]-quinazoline-1,3,6-triones (6a–d), 2-aryl-10-oxopyridazino[6,1-b]-quinazoline-3-thio-carboxamides (10a–d) and 2-aryl-3-nitro-1,2,3,4-tetrahydro-pyrid
Externí odkaz:
https://doaj.org/article/fa23141c920f459a82aee0ead231fcbf
Publikováno v:
Current Organic Chemistry. 22:2599-2633
Autor:
Mohamed A. A. Radwan, Hatem M. Gaber, Zeinab A. Muhammad, Thoraya A. Farghaly, Mahmuod M Elaasser
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 19:79-86
Background: Several biologically active indole alkaloids have been isolated from marine organisms over the previous few years. Many scientsts interested in synthesis of the marine azepinoindole alkaloids due to their wide range of bioliogical activie
Publikováno v:
RSC advances. 10(53)
Phosphoinositol-3-kinase enzyme (PI3K) plays a crucial role in driving oncogenic growth in various mammalian cells, particularly pancreatic cells. In the current study a series of novel furo[2,3-d]pyrimidine based-compounds were designed and synthesi
Autor:
Hassan M. Abdel-aziz, Zeinab A. Muhammad, Mohamad R. Abdelaziz, Hatem M. Gaber, Sobhi M. Gomha, Mahmoud M. Elaasser
Publikováno v:
Journal of Heterocyclic Chemistry. 55:530-536
Publikováno v:
Journal of Heterocyclic Chemistry. 54:2708-2716
2-Bromoacetyl-3-phenyl-1,3,4-thiadiazole derivative was synthesized and reacted with a number of heterocyclic amines to give a series of fused imidazole derivatives. Also, reaction of 2-bromoacetyl-3-phenyl-1,3,4-thiadiazole with o-phenylene diamine
Autor:
Hatem M. Gaber, Islam K. Matar, Mastora M Edress, Mohamed M. Amin, Zeinab A. Muhammad, Sobhi M. Gomha
Publikováno v:
Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry.
Background: A novel series of fused imidazole was prepared from the reaction of 2- bromoacetyl-3-phenyl-1,3,4-thiadiazole with various heterocyclic amines under microwave irradiation. The structures of all the novel products were elucidated based on