Zobrazeno 1 - 10
of 661
pro vyhledávání: '"Hatem E"'
Autor:
Hatem E. Gaffer, S. A. Mahmoud, M. S. El-Sedik, Tarek Aysha, Mohamed H. Abdel-Rhman, Ehab Abdel-latif
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract In this study, we synthesized new series of 5-oxo-2-phenyl-4-(arylsulfamoyl)sulphenyl) hydrazono)-4,5-dihydro-1H-pyrrole-3-carboxylate hybrids 4a-f with the goal of overcoming sulfonamide resistance and identifying novel therapeutic candidat
Externí odkaz:
https://doaj.org/article/62f11ae8d9ea4200a05f8e42fd5f0c61
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract 3-Amino-4,6-dimethylpyrazolopyridine was applied as a precursor for the synthesis of some new pyridopyrazolo-triazine and pyridopyrazolo-triazole derivatives through diazotization, followed by coupling with many 2-cyanoacetamide compounds, e
Externí odkaz:
https://doaj.org/article/5b5137706c474da29bd7ed53d5347ab0
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3304 (2023)
Alzheimer’s disease is a genetically complex disorder, and microarray technology provides valuable insights into it. However, the high dimensionality of microarray datasets and small sample sizes pose challenges. Gene selection techniques have emer
Externí odkaz:
https://doaj.org/article/9ee28093773140deb11638b52e15167f
Autor:
Isaac Yi Kim, Antonina Mitrofanova, Sukanya Panja, Joshua Sterling, Arnav Srivastava, Juliana Kim, Sinae Kim, Eric A. Singer, Thomas L. Jang, Saum Ghodoussipour, Biren Saraiya, Tina Mayer, Hatem E. Sabaawy, Bertram Yuh, Seok Soo Byun, Wun-Jae Kim, Shigeo Horie
Publikováno v:
Prostate International, Vol 10, Iss 2, Pp 75-79 (2022)
Purpose: Approximately 7% of patients with newly diagnosed prostate cancer (PCa) in the US will have have metastatic disease. The dogma that there is no role for surgery in this population has been questioned recently. Here we report long-term outcom
Externí odkaz:
https://doaj.org/article/2f501ee924ff43f5a17b5dc4d22e57f9
Autor:
Sahithi Pamarthy, Hatem E. Sabaawy
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract With advances in the discovery of the clinical and molecular landscapes of prostate cancer (PCa), implementation of precision medicine-guided therapeutic testing in the clinic has become a priority. Patient derived organoids (PDOs) are three
Externí odkaz:
https://doaj.org/article/f9c2766482634be1b94dbe3a2f1b40f7
Publikováno v:
Journal of the Egyptian Ophthalmological Society, Vol 114, Iss 1, Pp 21-29 (2021)
Settings This study was conducted in Mansoura Ophthalmic Center, Mansoura University, Egypt, during the period from January 2018 to January 2019. Purpose This study aimed to evaluate the visual outcomes, topographic features, endothelial cell densiti
Externí odkaz:
https://doaj.org/article/f26772c61477475fb6b02a1155436214
Autor:
Ibrahim Elbatal, Sadaf Khan, Tassaddaq Hussain, Mohammed Elgarhy, Naif Alotaibi, Hatem E. Semary, Mahmoud M. Abdelwahab
Publikováno v:
Axioms, Vol 11, Iss 8, p 361 (2022)
With the aim of identifying a probability model that not only correctly describes the stochastic behavior of extreme environmental factors such as excess rain, acid rain pH level, and concentrations of ozone, but also measures concentrations of NO2 a
Externí odkaz:
https://doaj.org/article/38a3c7b1191d47f4a3701fdf02564a34
Autor:
Christian Moya Gamboa, Kelly Jara, Sahithi Pamarthy, Liqiong Liu, Robert Aiken, Zhenggang Xiong, Shabbar Danish, Hatem E. Sabaawy
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100345- (2021)
Summary: Robust patient-derived platforms that recapitulate the cellular and molecular fingerprints of glioblastoma are crucial for developing effective therapies. Here, we describe a chemically defined protocol for 3D culture and propagation of glio
Externí odkaz:
https://doaj.org/article/555d439213354bf1a1b67ef8c4c2959d
Autor:
Michelle Chadwick, Chen Yang, Liqiong Liu, Christian Moya Gamboa, Kelly Jara, Howon Lee, Hatem E. Sabaawy
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101365- (2020)
Summary: Glioblastoma is the most common and deadly primary brain malignancy. Despite advances in precision medicine oncology (PMO) allowing the identification of molecular vulnerabilities in glioblastoma, treatment options remain limited, and molecu
Externí odkaz:
https://doaj.org/article/ffa5e9738668406b869a22d9ba6d5297
Autor:
Christian Moya Gamboa, Yujue Wang, Huiting Xu, Katarzyna Kalemba, Fredric E. Wondisford, Hatem E. Sabaawy
Publikováno v:
Cells, Vol 10, Iss 12, p 3280 (2021)
The liver is among the principal organs for glucose homeostasis and metabolism. Studies of liver metabolism are limited by the inability to expand primary hepatocytes in vitro while maintaining their metabolic functions. Human hepatic three-dimension
Externí odkaz:
https://doaj.org/article/898fa304cc0c4917b8f525354f2439d6