Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Hasso Scholz"'
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. :152-158
The influence of pertussis toxin on the effects of adenosine, the adenosine receptor agonist (-)-N6-phenylisopropyladenosine (PIA) and the m-cholinoceptor agonist carbachol on heart rate and atrioventricular (AV) conduction was investigated in sponta
This volume contains selected papers presented at the Sendai International Sympo sium on Molecular and Cellular Mechanisms of Cardiovascular Regulation held from May 10-12, 1995, to honor the contributions ofProfessorNorio Taira, Chairman of the De
The β2 subunit of nitric oxide-sensitive guanylyl cyclase is developmentally regulated in rat kidney
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 364:573-576
We have recently shown that nitric oxide activates the beta2 subunit of soluble guanylyl cyclase. In the present study, we show developmental regulation of this subunit. Analysis of mRNA expression by RT-PCR and RNase protection analysis in kidneys r
Nitric Oxide Activates the β2 Subunit of Soluble Guanylyl Cyclase in the Absence of a Second Subunit
Publikováno v:
Journal of Biological Chemistry. 276:30737-30743
Previously characterized mammalian soluble guanylyl cyclases form alpha/beta heterodimers that can be activated by the gaseous messenger, nitric oxide, and the novel guanylyl cyclase modulator YC-1. Four mammalian subunits have been cloned named alph
Publikováno v:
Chromatographia. 53:641-644
A sensitive high-performance liquid chromatographic method has been developed for the determination of the β-receptor blocker carvedilol in small volumes of plasma from pediatric patients. Carvedilol and the internal standard naftopidil were extract
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 753:421-425
A sensitive high-performance liquid chromatographic method using fluorescence detection has been developed for sotalol determination in small plasma samples of children and newborns with limited blood volume. In sample sizes of 100 microl of plasma,
Publikováno v:
Journal of Chromatographic Science. 39:121-124
A new high-performance liquid chromatographic method has been developed for the determination of the beta-receptor blocker carvedilol in human cardiac tissue. After homogenizing tissue samples in a microdismembrator, carvedilol and the internal stand
Autor:
Ana-Maria Bamberger, Jörg Kempfert, Thomas Löning, Sönke Behrends, Hasso Scholz, Markus Koglin
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:909-912
The cytoplasmic or soluble forms of guanylyl cyclase (sGC) are heme-containing heterodimeric enzymes that are regulated by nitric oxide (NO) and carbon monoxide (CO). These gaseous messenger molecules are produced in the human placenta and are potent
Publikováno v:
Biochemical Pharmacology. 59:713-717
The muscles of the corpus cavernosum of the penis relax in response to stimulation of non-adrenergic, non-cholinergic nerves or nitric oxide (NO)-donating drugs to elicit erection. It is generally assumed that NO mediates this effect via activation o
Autor:
Thomas Wieland, Monika Nose, Grit Kaspareit, Stefanie Gsell, Thomas Eschenhagen, Oliver Behrens, Hasso Scholz
Publikováno v:
The FASEB Journal. 14:17-26
Sensitization of adenylyl cyclase (AC) by increased expression of large isoforms of the stimulatory G-protein Gαs has been suggested as a mechanism that governs uterine quiescence during pregnancy. We quantified several components of the AC pathway