Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Hassane, Belabed"'
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Akademický článek
An LPAR5-antagonist that reduces nociception and increases pruriception
Autor: Jacqueline Langedijk, Erika Ivanna Araya, Amanda Ribeiro Barroso, Dagmar Tolenaars, Marc Nazaré, Hassane Belabed, Jens Schoene, Juliana Geremias Chichorro, Ronald Oude Elferink
Publikováno v: Frontiers in Pain Research, Vol 3 (2022)
IntroductionThe G-protein coupled receptor LPAR5 plays a prominent role in LPA-mediated pain and itch signaling. In this study we focus on the LPAR5-antagonist compound 3 (cpd3) and its ability to affect pain and itch signaling, both in vitro and in
Externí odkaz: https://doaj.org/article/b57a9af173bd488d918cfb9ed75bd1f1
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2
Akademický článek
Phosphoinositide Conversion Inactivates R‐RAS and Drives Metastases in Breast Cancer
Autor: Huayi Li, Lorenzo Prever, Myriam Y. Hsu, Wen‐Ting Lo, Jean Piero Margaria, Maria Chiara De Santis, Cristina Zanini, Marco Forni, Francesco Novelli, Salvatore Pece, Pier Paolo Di Fiore, Paolo Ettore Porporato, Miriam Martini, Hassane Belabed, Marc Nazare, Volker Haucke, Federico Gulluni, Emilio Hirsch
Publikováno v: Advanced Science, Vol 9, Iss 9, Pp n/a-n/a (2022)
Abstract Breast cancer is the most prevalent cancer and a major cause of death in women worldwide. Although early diagnosis and therapeutic intervention significantly improve patient survival rate, metastasis still accounts for most deaths. Here it i
Externí odkaz: https://doaj.org/article/ee0f506c019b414c91e9c0120c461dd3
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3
Antagonistic control of active surface integrins by myotubularin and phosphatidylinositol 3-kinase C2β in a myotubular myopathy model
Autor: Paula Samsó, Philipp A. Koch, York Posor, Wen-Ting Lo, Hassane Belabed, Marc Nazare, Jocelyn Laporte, Volker Haucke
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 119(40)
X-linked centronuclear myopathy (XLCNM) is a severe human disease without existing therapies caused by mutations in the phosphoinositide 3-phosphatase MTM1. Loss of MTM1 function is associated with muscle fiber defects characterized by impaired local
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e74a77c03bac0a05399242770eb48e4
https://pubmed.ncbi.nlm.nih.gov/36161941
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5
Advancing ASMS with LC‐MS/MS for the discovery of novel PDCL2 ligands from DNA‐encoded chemical library selections
Autor: Qiuji Ye, Hassane Belabed, Yong Wang, Zhifeng Yu, Murugesan Palaniappan, Jian‐Yuan Li, Stacey A. Kalovidouris, Kevin R. MacKenzie, Mingxing Teng, Damian W. Young, Yoshitaka Fujihara, Martin M. Matzuk
Publikováno v: Andrology.
A safe, effective, and reversible nonhormonal male contraceptive drug is greatly needed for male contraception as well as for circumventing the side effects of female hormonal contraceptives. Phosducin-like 2 (PDCL2) is a testis-specific phosphoprote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b8a2db42b1cdebed5aea0590166c3e
https://doi.org/10.1111/andr.13309
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6
An LPAR
Autor: Jacqueline, Langedijk, Erika Ivanna, Araya, Amanda Ribeiro, Barroso, Dagmar, Tolenaars, Marc, Nazaré, Hassane, Belabed, Jens, Schoene, Juliana Geremias, Chichorro, Ronald, Oude Elferink
Publikováno v: Frontiers in pain research (Lausanne, Switzerland). 3
The G-protein coupled receptor LPARNociceptive behavior in wild type mice was induced by formalin, carrageenan or prostaglandin E2 (PGEAs expected, nociceptive behavior (induced by formalin, carrageenan or PGECpd3 has
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7fbe3cc2bad7f79e17f857c72b943a97
https://pubmed.ncbi.nlm.nih.gov/35959236
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