Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Hassan Y. Ebrahim"'
Publikováno v:
AMB Express, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Aspergillus terreus has been reported to produce many bioactive metabolites that possess potential activities including anti-inflammatory, cytotoxic, and antimicrobial activities. In the present study, we report the isolation and identificat
Externí odkaz:
https://doaj.org/article/5435b8f6af38426d82b5b61acf10a23f
Autor:
Heba T. Khazaal, Mohamed T. Khazaal, Ahmed S. Abdel-Razek, Ahmed A. Hamed, Hassan Y. Ebrahim, Reham R. Ibrahim, Mokhtar Bishr, Yara E. Mansour, Rabab A. El Dib, Hesham S. M. Soliman
Publikováno v:
AMB Express, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Endophytic fungi allied to plants have sparked substantial promise in discovering new bioactive compounds. In this study, propagation of the endophytic fungus Alternaria alternata HE11 obtained from Colocasia esculanta leaves led to the isol
Externí odkaz:
https://doaj.org/article/c7cf3f25120b4851b6a212f175ac03fd
Autor:
Menna Fayek, Hassan Y. Ebrahim, Heba E. Elsayed, Mohamed S. Abdel-Aziz, Benson M. Kariuki, Fatma A. Moharram
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Prostate cancer (PCa) ranks as one of the most commonly diagnosed malignancies worldwide. Toxicity, lack of clinical efficacy, and development of resistance phenotypes are the main challenges in the control of prostate malignancies. Notably, castrati
Externí odkaz:
https://doaj.org/article/75aff30af88d470b8d43f8666dba24aa
Autor:
Khaldoun S. Abdelwahed, Abu Bakar Siddique, Hassan Y. Ebrahim, Mohammed H. Qusa, Ethar A. Mudhish, Ashkan H. Rad, Mourad Zerfaoui, Zakaria Y. Abd Elmageed, Khalid A. El Sayed
Publikováno v:
Marine Drugs, Vol 21, Iss 4, p 215 (2023)
Metastatic castration-resistant prostate cancer (mCRPC) cells can de novo biosynthesize their own cholesterol and overexpress proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 proved to contribute to mCRPC cell motility since PCSK9 knockdo
Externí odkaz:
https://doaj.org/article/400ea1119da0459dbfadecc21cc6a7b1
Autor:
Oliver C. McGehee, Hassan Y. Ebrahim, Ashkan H. Rad, Khaldoun S. Abdelwahed, Ethar A. Mudhish, Judy A. King, Iman E. Helal, Sharon A. Meyer, Khalid A. El Sayed
Publikováno v:
Molecules, Vol 28, Iss 3, p 1460 (2023)
The proprotein convertase subtilisin kexin type 9 (PCSK9) emerged as a molecular target of great interest for the management of cardiovascular disorders due to its ability to reduce low density lipoprotein (LDL) cholesterol by binding and targeting a
Externí odkaz:
https://doaj.org/article/c90d4d8640264cc68ab5a2f1d307554f
Autor:
Heba E. Elsayed, Reem A. Kamel, Reham R. Ibrahim, Ahmed S. Abdel-Razek, Mohamed A. Shaaban, Marcel Frese, Norbert Sewald, Hassan Y. Ebrahim, Fatma A. Moharram
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Endophytes are prolific producers of privileged secondary metabolites with diverse therapeutic potential, although their anticancer and antimicrobial potential still have a room for further investigation. Herein, seven known secondary metabolites nam
Externí odkaz:
https://doaj.org/article/1e2d02120f6e4cd1a39c1d3735ef8a3e
Autor:
Ethar A. Mudhish, Abu Bakar Siddique, Hassan Y. Ebrahim, Khaldoun S. Abdelwahed, Judy Ann King, Khalid A. El Sayed
Publikováno v:
Nutrients, Vol 14, Iss 7, p 1505 (2022)
Prostate cancer (PC) is the second leading cause of death in men in the US. PC has a high recurrence rate, and limited therapeutic options are available to prevent disease recurrence. The tryptophan-degrading enzymes 2,3-indoleamine dioxygenase (IDO1
Externí odkaz:
https://doaj.org/article/002123ebd3464c119a3f512ac3951944
Publikováno v:
Molecules, Vol 27, Iss 1, p 293 (2022)
In vitro anti-proliferative activity of Pinus palustris extract and its purified abietic acid was assessed against different human cancer cell lines (HepG-2, MCF-7 and HCT-116) compared to normal WI-38 cell line. Abietic acid showed more promising IC
Externí odkaz:
https://doaj.org/article/d39b5a6e3ada4de489b97b4a53089668
Autor:
Mohamed R. Akl, Nehad M. Ayoub, Hassan Y. Ebrahim, Mohamed M. Mohyeldin, Khaled Y. Orabi, Ahmed I. Foudah, Khalid A. El Sayed
Publikováno v:
Marine Drugs, Vol 13, Iss 1, Pp 288-311 (2015)
Receptor tyrosine kinases are key regulators of cellular growth and proliferation. Dysregulations of receptor tyrosine kinases in cancer cells may promote tumorigenesis by multiple mechanisms including enhanced cell survival and inhibition of cell de
Externí odkaz:
https://doaj.org/article/5acbd5d1df5142f0a36f2e348ea0ac85
Publikováno v:
Marine Drugs, Vol 12, Iss 4, Pp 2282-2304 (2014)
Sipholenol A is a natural sipholane triterpenoid isolated from the Red Sea sponge, Callyspongia siphonella. Previous studies showed the antimigratory and antiproliferative activities of the semisynthetic sipholenol A esters against breast cancer cell
Externí odkaz:
https://doaj.org/article/38572d8bdb514022adc438e99dee6324