Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hassan Sellak"'
Autor:
Caitlin V. Lewis, Hassan Sellak, Mariem A. Sawan, Giji Joseph, Trevor M. Darby, David VanInsberghe, Crystal R. Naudin, David R. Archer, Rheinallt M. Jones, W. Robert Taylor
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 5, Pp 199-210 (2023)
Abstract The intestinal microbiome has emerged as a potential contributor to the severity of sickle cell disease (SCD). We sought to determine whether SCD mice exhibit intestinal barrier dysfunction, inflammation, and dysbiosis. Using the Townes huma
Externí odkaz:
https://doaj.org/article/286f62f9ca5f48d3a0d039d671dbac67
Autor:
Ahmed S. Ibrahim, Sally Elshafey, Hassan Sellak, Khaled A. Hussein, Mohamed El-Sherbiny, Mohammed Abdelsaid, Nasser Rizk, Selina Beasley, Amany M. Tawfik, Sylvia B. Smith, Mohamed Al-Shabrawey
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 3, Pp 599-611 (2015)
Retinal hyperpermeability and subsequent macular edema is a cardinal feature of early diabetic retinopathy (DR). Here, we investigated the role of bioactive lipid metabolites, in particular 12/15-lipoxygenase (LOX)-derived metabolites, in this proces
Externí odkaz:
https://doaj.org/article/a9eac5bb558f49d4ab2ac1cd032e6672
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0144561 (2016)
Much attention has been directed to the physiological effects of nitric oxide (NO)-cGMP signaling, but virtually nothing is known about its hematologic effects. We reported for the first time that cGMP signaling induces human γ-globin gene expressio
Externí odkaz:
https://doaj.org/article/9e054fd6a8db418682fa4a5b418f217c
Autor:
Caitlin V. Lewis, Hassan Sellak, Laura Hansen, Giji Joseph, Julian Hurtado, David R. Archer, Ho-Wook Jun, Lou Ann Brown, W. Robert Taylor
Publikováno v:
Laboratory Investigation. 102:805-813
Sickle cell disease (SCD) is associated with repeated bouts of vascular insufficiency leading to organ dysfunction. Deficits in revascularization following vascular injury are evident in SCD patients and animal models. We aimed to elucidate whether e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e70ac0e42428f0046d64cb961e087fe
https://doi.org/10.1038/s41374-022-00780-0
https://doi.org/10.1038/s41374-022-00780-0
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Beta Thalassemia (BT) is an autosomal recessive hemoglobinopathy that affects 80 million people worldwide. Children with BT display an increase in carotid-intima media thickness, an early sign suggestive of premature atherosclerosis. However, it is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75195be38cbef0eada310c37fcb7d80c
https://doi.org/10.1161/atvb.41.suppl_1.mp17
https://doi.org/10.1161/atvb.41.suppl_1.mp17
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Introduction: It is well described that changes in the aortic media are crucial in the development of Abdominal Aortic Aneurysms (AAA), however the involvement of the endothelium is not as clear. The endothelium is the first vascular layer exposed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6b0c8f22f102d89dbbed1699d1df88
https://doi.org/10.1161/atvb.41.suppl_1.mp23
https://doi.org/10.1161/atvb.41.suppl_1.mp23
Publikováno v:
Journal of Blood Medicine
Tohru Ikuta,1 Hassan Sellak,1 Si-Yang Liu,2 Nadine Odo1 1Department of Anesthesiology and Perioperative Medicine, Medical College of Georgia, Augusta University, Augusta, GA, USA; 2Department of Biochemistry and Molecular Biology, Medical College of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963938e7db6f9e83838b53caea8f3a66
https://pubmed.ncbi.nlm.nih.gov/29950916
https://pubmed.ncbi.nlm.nih.gov/29950916
Autor:
Derick Okwan-Duodu, David R. Archer, Kai Xu, Laura Hansen, Wenxue Liu, Hassan Sellak, Giji Joseph, Rebecca D. Levit, Raymundo A. Quintana, Eric Shin, W. Robert Taylor
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Objectives: The link between chronic inflammation and poor cardiovascular outcomes has long been appreciated, but the regulation of immune cellular targets to improve cardiovascular health remains a challenge. Mounting evidence suggests that neutroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::073ae462b28fed43b5ab6536bf8b99da
https://doi.org/10.1161/atvb.38.suppl_1.028
https://doi.org/10.1161/atvb.38.suppl_1.028
Autor:
W. Robert Taylor, David R. Archer, Derick Okwan-Duodu, Hassan Sellak, Wenxue Liu, Laura Hansen, Raymundo A. Quintana, Giji Joseph
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Objectives: Despite the increased incidence and worse outcomes of cardiovascular diseases among African-Americans compared to the general population, the contribution of sickle cell trait (AS) to this racial disparity remains unknown. We aimed to del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::307064a6e9cd2d4db9ebd278faea460f
https://doi.org/10.1161/atvb.38.suppl_1.714
https://doi.org/10.1161/atvb.38.suppl_1.714
Publikováno v:
American Journal of Physiology-Cell Physiology. 307:C648-C656
The low-voltage-activated T-type Ca2+ channels play an important role in mediating the cellular responses to altered oxygen tension. Among three T-type channel isoforms, α1G, α1H, and α1I, only α1H was found to be upregulated under hypoxia. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436cb37310b38f1eef508db4d21076dd
https://doi.org/10.1152/ajpcell.00210.2014
https://doi.org/10.1152/ajpcell.00210.2014