Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hassan M. Mahsoub"'
Autor:
Bo Wang, Sakthivel Subramaniam, Debin Tian, Hassan M. Mahsoub, C. Lynn Heffron, Xiang-Jin Meng
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT Hepatitis E virus (HEV) is distinct from other hepatotropic viruses because it is zoonotic. HEV-1 and HEV-2 exclusively infect humans, whereas HEV-3 and HEV-4 are zoonotic. However, the viral and/or host factors responsible for cross-species
Externí odkaz:
https://doaj.org/article/1dfacaa8452e45d6b1dd3e35000d8e69
Autor:
Hassan M. Mahsoub, C. Lynn Heffron, Anna M. Hassebroek, Harini Sooryanarain, Bo Wang, Tanya LeRoith, Guillermo Raimundi Rodriguez, Debin Tian, Xiang-Jin Meng
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/6ab0fe69c47b449ab81c66bddca46eb5
Autor:
Charlotte Nyblade, Viviana Parreno, Peng Zhou, Casey Hensley, Vanessa Oakes, Hassan M. Mahsoub, Kelsey Kiley, Maggie Frazier, Annie Frazier, Yongrong Zhang, Hanping Feng, Lijuan Yuan
Publikováno v:
Gut Pathogens, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Clostridioides difficile (C. difficile) is a gram-positive, spore-forming, anaerobic bacterium known to be the most common cause of hospital-acquired and antibiotic-associated diarrhea. C. difficile infection rates are on the rise worldwide
Externí odkaz:
https://doaj.org/article/16b7795476164c36b4ea93091b3aaa6a
Autor:
Bo Wang, Hassan M. Mahsoub, Wen Li, C. Lynn Heffron, Debin Tian, Anna M. Hassebroek, Tanya LeRoith, Xiang-Jin Meng
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Chronic hepatitis E virus (HEV) infection has become a significant clinical problem that requires treatment in immunocompromised individuals. In the absence of an HEV-specific antiviral, ribavirin (RBV) has been used off-label, but treatment
Externí odkaz:
https://doaj.org/article/4429b6d48cac496a9f3480661787b546
Autor:
Hassan M. Mahsoub, C. Lynn Heffron, Anna M. Hassebroek, Harini Sooryanarain, Bo Wang, Tanya LeRoith, Guillermo Raimundi Rodríguez, Debin Tian, Xiang-Jin Meng
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Hepatitis E virus (HEV) causes adverse clinical outcomes in pregnant women, but the underlying mechanisms remain poorly understood. To delineate the mechanisms of pregnancy-associated adverse effects during HEV infection, we utilized a genot
Externí odkaz:
https://doaj.org/article/8b84c1aa43a74e1ba80d8773552696af
Autor:
Casey Hensley, Peng Zhou, Sofia Schnur, Hassan M. Mahsoub, Yu Liang, Min-Xuan Wang, Caroline Page, Lijuan Yuan, Victor Bronshtein
Publikováno v:
Vaccines, Vol 9, Iss 5, p 437 (2021)
Difficulties related to storage and transport of currently available live oral rotavirus vaccines can have detrimental consequences on the efficacy of the vaccines. Thus, there is a great need for thermostable vaccines that can eliminate the necessit
Externí odkaz:
https://doaj.org/article/a311cd83406b412a9dc9b6e389dff695
Autor:
Harini Sooryanarain, C. Lynn Heffron, Hassan M. Mahsoub, Anna M. Hassebroek, Bo Wang, Debin Tian, S. Ansar Ahmed, Xiang-Jin Meng
Publikováno v:
J Virol
Hepatitis E virus (HEV) infection usually results in a self-limiting acute disease; however, in infected pregnant women, it is associated with increased mortality and fulminant hepatic failure. Estrogen is known to be elevated during pregnancy, and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396ccf6c6b9de94c2d1b580169e20000
https://pubmed.ncbi.nlm.nih.gov/36102649
https://pubmed.ncbi.nlm.nih.gov/36102649
Autor:
Bo Wang, Hassan M. Mahsoub, Wen Li, C. Lynn Heffron, Debin Tian, Anna M. Hassebroek, Tanya LeRoith, Xiang-Jin Meng
HEV-3 causes chronic hepatitis E that requires antiviral therapy in immunosuppressed individuals. RBV is the main therapeutic option for chronic hepatitis E as an off-label use. Chronic hepatitis E virus (HEV) infection has become a significant clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8de98d6ac8f854f6dd712b69cfb4c5
https://hdl.handle.net/10919/114160
https://hdl.handle.net/10919/114160
Autor:
Anna M. Hassebroek, Harini Sooryanarain, Connie L. Heffron, Seth A. Hawks, Tanya LeRoith, Thomas E. Cecere, William B. Stone, Debra Walter, Hassan M. Mahsoub, Bo Wang, Debin Tian, Hannah M. Ivester, Irving C. Allen, Albert J. Auguste, Nisha K. Duggal, Chenming Zhang, Xiang‐Jin Meng
Publikováno v:
Journal of Medical Virology. 95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea1f0ea91dfa25382e12ae4c83c6b3b
https://doi.org/10.1002/jmv.28503
https://doi.org/10.1002/jmv.28503
Autor:
Bo Wang, Debin Tian, Harini Sooryanarain, Hassan M. Mahsoub, C. Lynn Heffron, Anna M. Hassebroek, Xiang-Jin Meng
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Hepatitis E virus (HEV) infection in pregnant women has a high incidence of developing fulminant hepatic failure (FHF) with significant mortality. Multiple amino acid changes in genotype 1 HEV (HEV-1) are reportedly linked to FHF clinical cases, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fb04cf1cf71b30b09020571c08cf12
https://doi.org/10.1073/pnas.2207503119
https://doi.org/10.1073/pnas.2207503119