Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hassan Lemjabbar"'
Autor:
Natalie S Lui, Yi-Wei Yang, Annemieke van Zante, Petra Buchanan, David M Jablons, Hassan Lemjabbar-Alaoui
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148911 (2016)
AIMS:Lung cancer is one of the most deadly cancers; median survival from diagnosis is less than one year in those with advanced disease. Novel lung cancer biomarkers are desperately needed. In this study, we evaluated SULF2 expression by immunohistoc
Externí odkaz:
https://doaj.org/article/2fec016d7c2e44a8837373281ecdec41
Autor:
Hassan Lemjabbar-Alaoui, Sukhvinder S Sidhu, Aklilu Mengistab, Marianne Gallup, Carol Basbaum
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17489 (2011)
Tobacco smoke predisposes humans and animals to develop lung tumors, but the molecular events responsible for this are poorly understood. We recently showed that signaling mechanisms triggered by smoke in lung cells could lead to the activation of a
Externí odkaz:
https://doaj.org/article/767bad90541f4f598c12f571092c33db
Autor:
Hassan Lemjabbar-Alaoui, Vijay Dasari, Sukhvinder S Sidhu, Aklilu Mengistab, Walter Finkbeiner, Marianne Gallup, Carol Basbaum
Publikováno v:
PLoS ONE, Vol 1, p e93 (2006)
Lung cancer is the leading cause of cancer death in the world, and greater than 90% of lung cancers are cigarette smoke-related. Current treatment options are inadequate, because the molecular basis of cigarette-induced lung cancer is poorly understo
Externí odkaz:
https://doaj.org/article/b10941c3ac87476caa926922151a88a5
Autor:
Lewis R. Roberts, Keun Soo Ahn, Rory L. Smoot, Michael Torbenson, Steven D. Rosen, Daniel R. O'Brien, Li He, Xin Luo, Hassan Lemjabbar-Alaoui, Mark S. Singer, Nellie A. Campbell
Publikováno v:
Hepatology
BACKGROUND AND AIMS Existing therapeutic approaches to treat cholangiocarcinoma (CCA) have limited effectiveness, prompting further study to develop therapies for CCA. We report a mechanistic role for the heparan sulfate editing enzyme sulfatase 2 (S
Publikováno v:
Experimental Lung Research. 47:261-279
Purpose Non-small lung (NSCLC) is the deadliest cancer, with survival measured in months. Earlier diagnosis using a robust biomarker would likely improve survival. This study aims to determine whether blood levels of the extracellular sulfatases (SUL
Autor:
Hassan Lemjabbar-Alaoui, Gavitt A. Woodard, Angelica Marrufo, Yi-Wei Yang, David M. Jablons, Jillian Chase
Publikováno v:
Experimental Lung Research. 47:9-25
Malignant pleural mesothelioma (MPM) is a rare and deadly malignancy. Current MPM therapies remain inadequate, and outcomes are often disappointing. New meaningful therapeutic approaches are urgently needed. Accumulating evidence indicates that the c
Publikováno v:
Biochimica et biophysica acta. General subjects, vol 1865, iss 2
Biochim Biophys Acta Gen Subj
Biochim Biophys Acta Gen Subj
Background Cell-surface heparan sulfate proteoglycans (HSPGs) function as receptors or co-receptors for ligand binding and mediate the transmission of critical extracellular signals into cells. The complex and dynamic modifications of heparan sulfate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81a4d53765ac798431c4fa82370db9a
https://escholarship.org/uc/item/0k22z401
https://escholarship.org/uc/item/0k22z401
Publikováno v:
American journal of cancer research. 10(8)
Poly (ADP-ribose) polymerase (PARP) has recently emerged as a central mediator in cancer resistance against numerous anticancer agents to include chemotherapeutic agents such as microtubule targeting agents and DNA damaging agents. Here, we describe
Autor:
Thomas Dierks, Hassan Lemjabbar-Alaoui, Steven D. Rosen, Mark S. Singer, Cherilyn A. Elwell, C Chan, Joanne N. Engel, Jung Hwa Kim
Publikováno v:
Cellular Microbiology. 15:1560-1571
The first step in attachment of Chlamydia to host cells is thought to involve reversible binding to host heparan sulfate proteoglycans (HSPGs), polymers of variably sulfated repeating disaccharide units coupled to diverse protein backbones. However,
Autor:
Yi-Wei Yang, Petra Buchanan, Natalie S. Lui, David M. Jablons, Annemieke van Zante, Hassan Lemjabbar-Alaoui
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148911 (2016)
PLoS ONE
PloS one, vol 11, iss 2
Lui, NS; Yang, Y-W; van Zante, A; Buchanan, P; Jablons, DM; & Lemjabbar-Alaoui, H. (2016). SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer. PLOS ONE, 11(2). doi: 10.1371/journal.pone.0148911. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2wx447c9
PLoS ONE
PloS one, vol 11, iss 2
Lui, NS; Yang, Y-W; van Zante, A; Buchanan, P; Jablons, DM; & Lemjabbar-Alaoui, H. (2016). SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer. PLOS ONE, 11(2). doi: 10.1371/journal.pone.0148911. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2wx447c9
Aims Lung cancer is one of the most deadly cancers; median survival from diagnosis is less than one year in those with advanced disease. Novel lung cancer biomarkers are desperately needed. In this study, we evaluated SULF2 expression by immunohistoc