Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Hassan Bousbaa"'
Autor:
Mafalda Calheiros-Lobo, João P. N. Silva, Bárbara Pinto, Luís Monteiro, Patrícia M. A. Silva, Hassan Bousbaa
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1196 (2024)
Head and neck cancer (HNC), the sixth most common cancer worldwide, is increasing in incidence, with oral squamous cell carcinoma (OSCC) as the predominant subtype. OSCC mainly affects middle-aged to elderly males, often occurring on the posterior la
Externí odkaz:
https://doaj.org/article/bfca26d2993e4974935d335e156a133d
Autor:
Bárbara Pinto, João P. N. Silva, Patrícia M. A. Silva, Daniel José Barbosa, Bruno Sarmento, Juliana Carvalho Tavares, Hassan Bousbaa
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 56 (2023)
Antimitotic compounds, targeting key spindle assembly checkpoint (SAC) components (e.g., MPS1, Aurora kinase B, PLK1, KLP1, CENPE), are potential alternatives to microtubule-targeting antimitotic agents (e.g., paclitaxel) to circumvent resistance and
Externí odkaz:
https://doaj.org/article/2ebe4a5eb1f54f99997c38cb49ff19a1
Autor:
Joana Moreira, Patrícia M. A. Silva, Matilde Barros, Lucília Saraiva, Madalena Pinto, Hassan Bousbaa, Honorina Cidade
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 879 (2023)
In this work, the design and synthesis of a new chalcone-trimethoxycinnamide hybrid (7) based on the combination of subunits of two promising antiproliferative compounds (CM-M345 (1) and BP-M345 (2)), previously obtained by our research group, are re
Externí odkaz:
https://doaj.org/article/4c6fd94802ad40ec8a789c435befe7c5
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1653 (2023)
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy, and radiation therapy, alone or in combination, are associated w
Externí odkaz:
https://doaj.org/article/ee510452300c4b2db058015a5525e5ca
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Antimitotic drugs arrest cells in mitosis through chronic activation of the spindle assembly checkpoint (SAC), leading to cell death. However, drug-treated cancer cells can escape death by undergoing mitotic slippage, due to premature mitoti
Externí odkaz:
https://doaj.org/article/c3dad4e66e3e4f7d9cc9384d70d477bc
Publikováno v:
RevSALUS, Vol 4, Iss Sup (2022)
Externí odkaz:
https://doaj.org/article/ddd69742c5464b02afaee365efc0874b
Publikováno v:
RevSALUS, Vol 4, Iss Sup (2022)
Externí odkaz:
https://doaj.org/article/c887029178654453a3e64806fdd297dc
Publikováno v:
RevSALUS, Vol 4, Iss Sup (2022)
Externí odkaz:
https://doaj.org/article/904e5784b902426cbaae52756647b90a
Autor:
Mariana Nunes, Patrícia M. A. Silva, Ricardo Coelho, Carla Pinto, Albina Resende, Hassan Bousbaa, Gabriela M. Almeida, Sara Ricardo
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/5a396ba15d154d8faefbe8a24d354468
Autor:
Hassan Bousbaa
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 605 (2023)
Owing to the exceptional complexity of the development and progression of cancer, diverse cancer types are alarmingly increasing worldwide [...]
Externí odkaz:
https://doaj.org/article/1a43591c311f4b7293810fa1e8c4653b