Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hassan, Shahbakhti"'
Autor:
Z. A. Bascal, Hassan Shahbakhti, Sami A. Znati, Adam Westhorpe, Jessica Prince, Petra Vlckova, Marcos Duran Vasquez, Chiara De Vellis, Marilena Loizidou, Rebecca Carter, Ricky A. Sharma
Publikováno v:
Cancers
Volume 12
Issue 7
Cancers, Vol 12, Iss 1878, p 1878 (2020)
Volume 12
Issue 7
Cancers, Vol 12, Iss 1878, p 1878 (2020)
Hepatocellular Carcinoma (HCC) is increasing in incidence worldwide and requires new approaches to therapy. The combination of anti-angiogenic drug therapy and radiotherapy is one promising new approach. The anti-angiogenic drug vandetanib is a tyros
Autor:
Geoffrey S. Baldwin, Rory J. O’Neill, Ashok S. Bhagwat, Hassan Shahbakhti, Erik Zmuda, Olga V. Vorob'eva
Publikováno v:
Journal of Biological Chemistry. 278:20526-20532
The gene for the mismatch-specific uracil glycosylase (MUG) was identified in the Escherichia coli genome as a sequence homolog of the mammalian thymine DNA glycosylase, with activity against uracil in U.G mismatches. Subsequently, 3,N4-ethenocytosin
Autor:
Marie I. Homburg, Hassan Shahbakhti, Bernd Epe, Gerard M. J. Beijersbergen van Henegouwen, Arie A. Vink, R. M. Azurdia, Marie-Jose S.T. Steenwinkel, Francis McArdle, Lesley E. Rhodes, Ralf M. W. Moison, Michael P. Dean
Publikováno v:
Carcinogenesis. 24:919-925
Dietary omega-3 polyunsaturated fatty acids (ω-3 PUFAs) protect against photocarcinogenesis in animals, but prospective human studies are scarce. The mechanism(s) underlying the photoprotection are uncertain, although ω-3 PUFAs may influence oxidat
Publikováno v:
Biochemical Pharmacology. 53:1115-1121
Two versions of the comet assay have been used to identify the difference in the modes of action of AZQ (2,5-diaziridinyl-3,6-bis(carboethoxyamino)-1,4-benzoquinone) and BZQ (2,5-diaziridinyl-3,6-bis(ethanolamino)-1,4-benzoquinone)in human leukaemia
Publikováno v:
Antibody Engineering ISBN: 9783642011467
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6371f5520ecd7e645182febf5bea493
https://doi.org/10.1007/978-3-642-01147-4_38
https://doi.org/10.1007/978-3-642-01147-4_38
Autor:
Hassan, Shahbakhti, Rachel E B, Watson, Richard M, Azurdia, Christiana Z, Ferreira, Marjan, Garmyn, Lesley E, Rhodes
Publikováno v:
Photochemistry and photobiology. 80(2)
Dietary omega-3 polyunsaturated fatty acids (omega-3 PUFA) reduce sunburn, an acute inflammatory response, in humans. We assessed whether this may be mediated by reduced ultraviolet-B (UV-B) induction of proinflammatory mediators tumor necrosis facto
Autor:
Lesley E. Rhodes, Christiana Z. Ferreira, R. M. Azurdia, Rachel E.B. Watson, Marjan Garmyn, Hassan Shahbakhti
Publikováno v:
Photochemistry and Photobiology.
Mismatch uracil glycosylase from Escherichia coli: a general mismatch or a specific DNA glycosylase?
Autor:
Rory J, O'Neill, Olga V, Vorob'eva, Hassan, Shahbakhti, Erik, Zmuda, Ashok S, Bhagwat, Geoffrey S, Baldwin
Publikováno v:
The Journal of biological chemistry. 278(23)
The gene for the mismatch-specific uracil glycosylase (MUG) was identified in the Escherichia coli genome as a sequence homolog of the mammalian thymine DNA glycosylase, with activity against uracil in U.G mismatches. Subsequently, 3,N4-ethenocytosin
Autor:
L D Hope-Stone, D O'Malley, Hassan Shahbakhti, Surinder K. Sharma, E Tsiompanou, Ajw Hilson, Richard H. J. Begent, L Gumbrell, David C. Blakey, Daniel Hochhauser, K L Adamson, Janet Martin, A J Green, SD Webley, A Robbins, L Sena, R. J. Francis, Caroline J. Springer
Publikováno v:
British Journal of Cancer
Antibody-directed enzyme prodrug therapy is a targeted therapy in which a prodrug is activated selectively at the tumour site by an enzyme, which has been targeted to the tumour by an antibody (antibody-enzyme conjugate). Previous clinical trials hav
Autor:
Jimmy D. Bell, A Mayer, Geoff Boxer, Berend Tolner, Sweta Parker, Caroline J. Springer, Natalie Griffin, Richard H. J. Begent, Edward Grudus, Hassan Shahbakhti, Surinder K. Sharma, Duncan K. Wilkins, Kerry A. Chester, A J Green, R. J. Francis, Janet A Hartley
Publikováno v:
Cancer Research. 68:LB-200
Background: Antibody Directed Enzyme Prodrug Therapy (ADEPT) uses an antibody linked to an enzyme to deliver enzyme selectively to tumor deposits. When enzyme has localized to the tumor and cleared from the circulation, a low-toxicity prodrug is give