IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition.

Autor: Haslund-Gourley BS; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Woloszczuk K; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Hou J; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Connors J; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Cusimano G; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Bell M; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Taramangalam B; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Fourati S; Emory University, Atlanta, GA, USA., Mege N; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Bernui M; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Altman MC; Benaroya Research Institute, Seattle, WA, USA., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., van Bakel H; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY, USA., Maecker HT; Stanford University, Stanford, CA, USA., Rouphael N; Emory University, Atlanta, GA, USA., Diray-Arce J; Clinical & Data Coordinating Center (CDCC); Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA., Wigdahl B; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Kutzler MA; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Cairns CB; Drexel University/Tower Health Hospital, Philadelphia, PA, USA., Haddad EK; Drexel University/Tower Health Hospital, Philadelphia, PA, USA. ee336@drexel.edu., Comunale MA; Drexel University/Tower Health Hospital, Philadelphia, PA, USA. mc375@drexel.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Jan 09; Vol. 15 (1), pp. 404. Date of Electronic Publication: 2024 Jan 09.

Large-Scale Sequencing of Borreliaceae for the Construction of Pan-Genomic-Based Diagnostics.

Autor: Socarras KM; Center for Advanced Microbial Processing, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA 19102, USA.; Center for Genomic Sciences, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA 19102, USA.; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19102, USA., Haslund-Gourley BS; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19102, USA., Cramer NA; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, 1112 East Clay Street, Room 101 Health Sciences Research Building, Richmond, VA 23298, USA.; Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298, USA., Comunale MA; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19102, USA., Marconi RT; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, 1112 East Clay Street, Room 101 Health Sciences Research Building, Richmond, VA 23298, USA.; Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298, USA., Ehrlich GD; Center for Advanced Microbial Processing, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA 19102, USA.; Center for Genomic Sciences, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA 19102, USA.; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, 1112 East Clay Street, Room 101 Health Sciences Research Building, Richmond, VA 23298, USA.; Center for Surgical Infections and Biofilms, Institute for Molecular Medicine and Infectious Disease, Drexel University College of Medicine, Philadelphia, PA 19102, USA.

Publikováno v: Genes [Genes (Basel)] 2022 Sep 08; Vol. 13 (9). Date of Electronic Publication: 2022 Sep 08.

Establishment of blood glycosidase activities and their excursions in sepsis.

Autor: Haslund-Gourley BS; Sanford-Burnham-Prebys Medical Discovery Institute, Infectious and Inflammatory Diseases Center, La Jolla, CA 92037, USA., Aziz PV; Sanford-Burnham-Prebys Medical Discovery Institute, Infectious and Inflammatory Diseases Center, La Jolla, CA 92037, USA., Heithoff DM; Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, CA 93106, USA., Restagno D; Sanford-Burnham-Prebys Medical Discovery Institute, Infectious and Inflammatory Diseases Center, La Jolla, CA 92037, USA., Fried JC; Department of Pulmonary and Critical Care Medicine, Cottage Hospital of Santa Barbara, Santa Barbara, CA 93105, USA., Ilse MB; Department of Chemistry, Biochemistry, Bielefeld University, D-33615, Germany., Bäumges H; Department of Chemistry, Biochemistry, Bielefeld University, D-33615, Germany., Mahan MJ; Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, CA 93106, USA., Lübke T; Department of Chemistry, Biochemistry, Bielefeld University, D-33615, Germany., Marth JD; Sanford-Burnham-Prebys Medical Discovery Institute, Infectious and Inflammatory Diseases Center, La Jolla, CA 92037, USA.

Publikováno v: PNAS nexus [PNAS Nexus] 2022 Jul 11; Vol. 1 (3), pp. pgac113. Date of Electronic Publication: 2022 Jul 11 (Print Publication: 2022).