Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hasiyet Memetimin"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Lipoprotein lipase (LPL) hydrolyzes the triglyceride core of lipoproteins and also functions as a bridge, allowing for lipoprotein and cholesterol uptake. Transgenic mice expressing LPL in adipose tissue under the control of the adiponectin
Externí odkaz:
https://doaj.org/article/7319c772f3da445b8eaa53bc8251b45b
Macrophages expressing uncoupling protein 1 increase in adipose tissue in response to cold in humans
Autor:
Brian S. Finlin, Hasiyet Memetimin, Amy L. Confides, Beibei Zhu, Philip M. Westgate, Esther E. Dupont-Versteegden, Philip A. Kern
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Acute cold induces beige adipocyte protein marker expression in human subcutaneous white adipose tissue (SC WAT) from both the cold treated and contralateral leg, and the immune system regulates SC WAT beiging in mice. Cold treatment signifi
Externí odkaz:
https://doaj.org/article/6c5044d732df4d2eb6330566329c9ef6
Autor:
Brian S. Finlin, Hasiyet Memetimin, Beibei Zhu, Amy L. Confides, Hemendra J. Vekaria, Riham H. El Khouli, Zachary R. Johnson, Philip M. Westgate, Jianzhong Chen, Andrew J. Morris, Patrick G. Sullivan, Esther E. Dupont-Versteegden, Philip A. Kern
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
BACKGROUND Beige and brown adipose tissue (BAT) are associated with improved metabolic homeostasis. We recently reported that the β3-adrenergic receptor agonist mirabegron induced beige adipose tissue in obese insulin-resistant subjects, and this wa
Externí odkaz:
https://doaj.org/article/4492e0bd5623473ca8f914b2b47f39c5
Autor:
Amy L. Confides, Esther E. Dupont-Versteegden, Hemendra J. Vekaria, Brian S. Finlin, Philip A. Kern, Patrick G. Sullivan, Hasiyet Memetimin, Jianzhong Chen, Riham H. El Khouli, Philip M. Westgate, Andrew J. Morris, Beibei Zhu, Zachary R. Johnson
Publikováno v:
Journal of Diabetes Investigation
BACKGROUNDBeige adipose tissue is associated with improved glucose homeostasis in mice. Adipose tissue contains β3-adrenergic receptors (β3-ARs), and this study was intended to determine whether the treatment of obese, insulin-resistant humans with
Autor:
Andrew J. Morris, Philip A. Kern, El Khouli Rh, Zhu B, Brian S. Finlin, Esther E. Dupont-Versteegden, Patrick G. Sullivan, Hasiyet Memetimin, Zachary R. Johnson, Philip M. Westgate, Hemendra J. Vekaria, Amy L. Confides, Chen J
Publikováno v:
Yearbook of Paediatric Endocrinology.
Autor:
Hasiyet Memetimin, Philip A. Kern, Beibei Zhu, Philip M. Westgate, Brian S. Finlin, Zachary R. Johnson, Andrew J. Morris, Amy L. Confides, Patrick G. Sullivan, Riham H. El Khouli, Hemendra J. Vekaria, Esther E. Dupont-Versteegden, Jianzhong Chen
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 6 (2021)
JCI Insight, Vol 6, Iss 6 (2021)
BACKGROUND Beige and brown adipose tissue (BAT) are associated with improved metabolic homeostasis. We recently reported that the β3-adrenergic receptor agonist mirabegron induced beige adipose tissue in obese insulin-resistant subjects, and this wa
Autor:
Zachary Johnson, Esther E. Dupont-Versteegden, Patrick G. Sullivan, Hasiyet Memetimin, Beibei Zhu, Philip M. Westgate, Hemendra J. Vekaria, Philip A. Kern, Amy L. Confides, Brian S. Finlin
Publikováno v:
Diabetes. 69
Treatment of subjects who are obese/insulin resistant with the β3AR agonist mirabegron resulted in increased beige adipose tissue, without a change in brown adipose tissue (BAT), along with an improvement in glucose tolerance, HbA1c, and an increase
Autor:
Philip M. Westgate, Esther E. Dupont-Versteegden, Mary C. Boulanger, Brian S. Finlin, Hasiyet Memetimin, Kyle W. Taylor, Beibei Zhu, Philip A. Kern, Zachary R. Johnson, Amy L. Confides
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
In a recent study, repeated cold application induced beiging in subcutaneous white adipose tissue (SC WAT) of humans independent of body mass index. To identify factors that promote or inhibit beiging, we performed multiplex analysis of gene expressi
Autor:
Zachary R. Johnson, Hasiyet Memetimin, Amy L. Confides, Brian S. Finlin, Philip A. Kern, Esther E. Dupont-Versteegden, Beibei Zhu
Publikováno v:
Diabetes. 68
Brown adipose tissue (BAT) is associated with improved metabolic homeostasis in humans, and studies in rodents indicate that subcutaneous white adipose tissue (SC WAT) beiging, which involves increased uncoupling protein 1 (UCP1) expression, also is
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 315(6)
Thrombospondin 1 (TSP1) is a multifunctional matricellular protein. Recent studies demonstrate that TSP1 is highly expressed in adipose tissue (AT) and positively associated with AT inflammation and insulin resistance (IR). In this study, the contrib