Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hasini Jayatilaka"'
Autor:
Estibaliz Gómez-de-Mariscal, Vanesa Guerrero, Alexandra Sneider, Hasini Jayatilaka, Jude M. Phillip, Denis Wirtz, Arrate Muñoz-Barrutia
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Biomedical research has come to rely on p-values as a deterministic measure for data-driven decision-making. In the largely extended null hypothesis significance testing for identifying statistically significant differences among groups of o
Externí odkaz:
https://doaj.org/article/acc2d674dbab488ba4d3b0327ac6fb30
Autor:
Jude M. Phillip, Nahuel Zamponi, Madonna P. Phillip, Jena Daya, Shaun McGovern, Wadsworth Williams, Katherine Tschudi, Hasini Jayatilaka, Pei-Hsun Wu, Jeremy Walston, Denis Wirtz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Phillip and colleagues use dermal fibroblasts from a range of donors to quantify cell motility in ageing cells. They show that the age-dependent decrease in cell motility is not due to the reduced motility of all cells, but results from the fractiona
Externí odkaz:
https://doaj.org/article/71fdc1a8a32e4767a22e8879599c3e9f
Autor:
Hasini Jayatilaka, Pranay Tyle, Jonathan J. Chen, Minsuk Kwak, Julia Ju, Hyun Ji Kim, Jerry S. H. Lee, Pei-Hsun Wu, Daniele M. Gilkes, Rong Fan, Denis Wirtz
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Tumor cell proliferation and migration, key drivers of metastasis, can be mechanistically coupled in matrix embedded human sarcoma and carcinoma cells through cell density via a synergistic, paracrine signaling mechanism between Interleukins 6/8. Inh
Externí odkaz:
https://doaj.org/article/dbe0f12d5d9d4050b25725c41849802f
Autor:
Daniele M. Gilkes, Gregg L. Semenza, Denis Wirtz, Pei-Hsun Wu, Meng Horng Lee, Debangshu Samanta, Lisha Xiang, Sun Joo Lee, Hasini Jayatilaka, Jungmin Byun, I Chae Ye, Inês Godet, Julia A. Ju
Characterization of ITGA5 expression in MDA-MB-231 subclones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d41fbeb3842a322c560a8094d04bd99
https://doi.org/10.1158/1541-7786.22511178.v1
https://doi.org/10.1158/1541-7786.22511178.v1
Autor:
Daniele M. Gilkes, Gregg L. Semenza, Denis Wirtz, Pei-Hsun Wu, Meng Horng Lee, Debangshu Samanta, Lisha Xiang, Sun Joo Lee, Hasini Jayatilaka, Jungmin Byun, I Chae Ye, Inês Godet, Julia A. Ju
Supplemental Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa1a382fe910a9703d8aada734b1530
https://doi.org/10.1158/1541-7786.22511163
https://doi.org/10.1158/1541-7786.22511163
Autor:
Debonil Maity, Pratik Kamat, Nahuel Zamponi, Hasini Jayatilaka, Anjil Giri, Wenxuan Du, Adrian Johnston, Bartholomew Starich, Michelle Karl, Anshika Agrawal, Deanna Riley, Leandro Venturutti, Ari Melnick, Leandro Cerchietti, Jeremy Walston, Jude M. Phillip
Cell motility is essential to many biological processes as cells navigate and interact within their local microenvironments. Currently, most methods to quantify cell motility rely on the ability to follow and track individual cells. However, results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d772cf54484cc64582520854dfd290b
https://doi.org/10.1101/2022.09.21.508955
https://doi.org/10.1101/2022.09.21.508955
Autor:
Katherine Tschudi, Shaun McGovern, Jude M. Phillip, Denis Wirtz, Hasini Jayatilaka, Jena Daya, Wadsworth Williams, Madonna P. Phillip, Jeremy D. Walston, Pei Hsun Wu, Nahuel Zamponi
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Ageing in humans is associated with the decreased capacity to regulate cell physiology. Cellular properties, such as cell morphology and mechanics, encode ageing information, and can therefore be used as robust biomarkers of ageing. Using a panel of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac1bdb00ee272693e00aa7ad2319cf5
Autor:
Estibaliz Gómez-de-Mariscal, Arrate Muñoz-Barrutia, Jude M. Phillip, Hasini Jayatilaka, Denis Wirtz, Alexandra Sneider, Vanesa Guerrero
Biomedical research has come to rely on p-values as a deterministic measure for data-driven decision making. In the largely extended null-hypothesis significance testing (NHST) for identifying statistically significant differences among groups of obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e1b5e3ba21840a13634884dc14ee225
https://doi.org/10.1101/2019.12.17.878405
https://doi.org/10.1101/2019.12.17.878405
Autor:
Inês Godet, Lisha Xiang, Julia A. Ju, Gregg L. Semenza, I Chae Ye, Jungmin Byun, Hasini Jayatilaka, Pei Hsun Wu, Meng-Horng Lee, Debangshu Samanta, Sun Joo Lee, Denis Wirtz, Daniele M. Gilkes
Publikováno v:
Molecular Cancer Research. 15:723-734
Metastasis is the leading cause of breast cancer mortality. Previous studies have implicated hypoxia-induced changes in the composition and stiffness of the extracellular matrix (ECM) in the metastatic process. Therefore, the contribution of potentia
Autor:
Pei Hsun Wu, Jerry S.H. Lee, Rong Fan, Jonathan J. Chen, Daniele M. Gilkes, Denis Wirtz, Julia A. Ju, Minsuk Kwak, Hyun Ji Kim, Pranay Tyle, Hasini Jayatilaka
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Following uncontrolled proliferation, a subset of primary tumour cells acquires additional traits/mutations to trigger phenotypic changes that enhance migration and are hypothesized to be the initiators of metastasis. This study reveals an adaptive m