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of 7
pro vyhledávání: '"Hasen X"'
Autor:
Supinder S. Bedi, Michael C. Scott, Max A. Skibber, Akshita Kumar, Henry W. Caplan, Hasen Xue, David Sequeira, Alison L. Speer, Fanni Cardenas, Franciska Gudenkauf, Karen Uray, Amit K. Srivastava, Alan R. Prossin, Charles S. Cox
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Traumatic brain injury (TBI) results in activated microglia. Activated microglia can be measured in vivo by using positron emission topography (PET) ligand peripheral benzodiazepine receptor standardized uptake values (PBR28suv). Cell based
Externí odkaz:
https://doaj.org/article/3f8dcf5c326345358095521f0c347884
Autor:
Henry W Caplan, Karthik S Prabhakara, Naama E Toledano Furman, Soheil Zorofchian, Cecilia Martin, Hasen Xue, Scott D Olson, Charles S Cox
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251601 (2021)
Traumatic brain injury (TBI) causes both physical disruption of the blood brain barrier (BBB) and altered immune responses that can lead to significant secondary brain injury and chronic inflammation within the central nervous system (CNS). Cell ther
Externí odkaz:
https://doaj.org/article/16a3ed46c4164efd89a59ec139a4fb13
Autor:
Henry W. Caplan, Fanni Cardenas, Franciska Gudenkauf, Pamela Zelnick, Hasen Xue, Charles S. Cox, Supinder S. Bedi
Publikováno v:
ASN Neuro, Vol 12 (2020)
Traumatic brain injury (TBI) disrupts the complex arrangement of glia and neuronal cells in the central nervous system. Microglia, the resident immune cells, survey the cellular milieu under homeostatic conditions and play a neuroprotective role via
Externí odkaz:
https://doaj.org/article/6713315c8a4341039eaf30b127adc89a
Autor:
Supinder S. Bedi, Benjamin M. Aertker, George P. Liao, Henry W. Caplan, Deepa Bhattarai, Fanni Mandy, Franciska Mandy, Luis G. Fernandez, Pamela Zelnick, Matthew B. Mitchell, Walter Schiffer, Margaret Johnson, Emma Denson, Karthik Prabhakara, Hasen Xue, Philippa Smith, Karen Uray, Scott D. Olson, Robert W. Mays, Charles S. Cox
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background Traumatic brain injury (TBI) is a major cause of death and disability. TBI results in a prolonged secondary central neuro-inflammatory response. Previously, we have demonstrated that multiple doses (2 and 24 h after TBI) of multip
Externí odkaz:
https://doaj.org/article/cce291713bdd42509e6bebc93fc98d84
Akademický článek
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Autor:
George P. Liao, Benjamin M. Aertker, Daniel J. Kota, Karthik S. Prabhakara, Philipp Smith, Robert A. Hetz, Hasen Xue, Supinder Bedi, Scott D. Olson, Charles S. Cox
Publikováno v:
ADMET and DMPK, Vol 3, Iss 3, Pp 182-189 (2015)
The blood brain barrier plays an important role in traumatic brain injury, serving at the crossroads of secondary injury and potential therapies. In regards to trauma, this barrier contains an array of cellular and molecular components that protect t
Externí odkaz:
https://doaj.org/article/b8bb097843cf4017ad11c3a8874f2bf8
Autor:
Junling Gao, Raymond J. Grill, Tiffany J. Dunn, Supinder Bedi, Javier Allende Labastida, Robert A. Hetz, Hasen Xue, Jason R. Thonhoff, Douglas S. DeWitt, Donald S. Prough, Charles S. Cox M.D., Ping Wu M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Neural stem cells (NSCs) promote recovery from brain trauma, but neuronal replacement is unlikely the sole underlying mechanism. We hypothesize that grafted NSCs enhance neural repair at least partially through modulating the host immune response aft
Externí odkaz:
https://doaj.org/article/7b3bf25a8f5b48fab8f6150528fa5b1b