Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids.

Autor: Kjar A; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Haschert MR; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Zepeda JC; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA., Simmons AJ; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Yates A; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA., Chavarria D; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Fernandez M; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Robertson G; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Abdulrahman AM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Kim H; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Marguerite NT; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Moen RK; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Drake LE; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA., Curry CW; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., O'Grady BJ; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA., Gama V; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA., Lau KS; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA; Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA; Chemical and Physical Biology Program, Vanderbilt University School of Medicine, Nashville, TN, USA; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Grueter B; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA; Department of Anesthesiology, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA., Brunger JM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA., Lippmann ES; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, USA; Interdisciplinary Materials Science Program, Vanderbilt University, Nashville, TN, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN, USA; Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: ethan.s.lippmann@vanderbilt.edu.

Publikováno v: Cell reports [Cell Rep] 2024 Nov 26; Vol. 43 (11), pp. 114874. Date of Electronic Publication: 2024 Oct 17.