Persistent Properties of a Subpopulation of Cancer Cells Overexpressing the Hedgehog Receptor Patched.

Autor: Feliz Morel, Álvaro Javier¹ (AUTHOR) javitto28@gmail.com, Hasanovic, Anida¹ (AUTHOR) anida160@hotmail.com, Morin, Aurélie² (AUTHOR) aurelie.morin@gmail.com, Prunier, Chloé³ (AUTHOR) chloe.prunier@inovotion.com, Magnone, Virginie¹ (AUTHOR) magnone@ipmc.cnrs.fr, Lebrigand, Kevin¹ (AUTHOR) lebrigand@ipmc.cnrs.fr, Aouad, Amaury¹ (AUTHOR) amaury.aouad@univ-cotedazur.fr, Cogoluegnes, Sarah¹ (AUTHOR) cogoluegnes@ipmc.cnrs.fr, Favier, Judith² (AUTHOR) judith.favier@inserm.fr, Pasquier, Claude⁴ (AUTHOR) claude.pasquier@univ-cotedazur.fr, Mus-Veteau, Isabelle¹ (AUTHOR) mus-veteau@ipmc.cnrs.fr

Publikováno v: Pharmaceutics. May2022, Vol. 14 Issue 5, p988-988. 27p.

L'astemizole sensibilise les cellules de carcinome corticosurrénalien à la doxorubicine en inhibant l'azctivité d'efflux de drogues de Patched

Autor: Hasanovic, Anida, Simsir, Méliné, FS, Choveau, Lalli, Enzo, Mus-Veteau, Isabelle

Publikováno v: Biomedicines
Biomedicines, MDPI, 2020, 8, ⟨10.3390/biomedicines8080251⟩

International audience; Adrenocortical carcinoma (ACC) presents a high risk of relapse and metastases with outcomes not improving despite extensive research and new targeted therapies. We recently showed that the Hedgehog receptor Patched is expresse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::99b1d868d01dfcef4d97794d8f2fc3f5
https://hal.univ-cotedazur.fr/hal-02917455/document

Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo

Autor: Hasanovic, Anida, Ruggiero, Carmen, Jung, Sara, Rapa, Ida, Signetti, Laurie, Ben Hadj, Monia, Terzolo, Massimo, Beuschlein, Felix, Volante, Marco, Hantel, Constanze, Lalli, Enzo, Mus-Veteau, Isabelle

Publikováno v: International Journal of Cancer
International Journal of Cancer, Wiley, 2018, 143 (1), pp.199-211. ⟨10.1002/ijc.31296⟩

One of the crucial challenges in the clinical management of cancer is the resistance to chemotherapeutics. We recently demonstrated that the Hedgehog receptor Patched, which is overexpressed in many recurrent and metastatic cancers, is a multidrug tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::45ba9fb2124f85d8a761ffcbce781fbc
https://www.zora.uzh.ch/id/eprint/149141/

Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo.

Autor: Hasanovic, Anida, Ruggiero, Carmen, Jung, Sara, Rapa, Ida, Signetti, Laurie, Ben Hadj, Monia, Terzolo, Massimo, Beuschlein, Felix, Volante, Marco, Hantel, Constanze, Lalli, Enzo, Mus‐Veteau, Isabelle

Publikováno v: International Journal of Cancer; Jul2018, Vol. 143 Issue 1, p199-211, 13p

Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo.

Autor: Hasanovic A; Université Côte d'Azur, Sophia Antipolis, Valbonne, France.; CNRS UMR7275, Sophia Antipolis, Valbonne, France.; NEOGENEX CNRS International Associated Laboratory, Sophia Antipolis, Valbonne, France.; Institut de Pharmacologie Moléculaire et Cellulaire, Sophia Antipolis, Valbonne, France., Ruggiero C; Université Côte d'Azur, Sophia Antipolis, Valbonne, France.; CNRS UMR7275, Sophia Antipolis, Valbonne, France.; NEOGENEX CNRS International Associated Laboratory, Sophia Antipolis, Valbonne, France.; Institut de Pharmacologie Moléculaire et Cellulaire, Sophia Antipolis, Valbonne, France., Jung S; Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität, Munich, Germany., Rapa I; Department of Oncology, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy., Signetti L; Université Côte d'Azur, Sophia Antipolis, Valbonne, France.; CNRS UMR7275, Sophia Antipolis, Valbonne, France.; NEOGENEX CNRS International Associated Laboratory, Sophia Antipolis, Valbonne, France.; Institut de Pharmacologie Moléculaire et Cellulaire, Sophia Antipolis, Valbonne, France., Ben Hadj M; Université Côte d'Azur, Sophia Antipolis, Valbonne, France.; CNRS UMR7275, Sophia Antipolis, Valbonne, France.; NEOGENEX CNRS International Associated Laboratory, Sophia Antipolis, Valbonne, France.; Institut de Pharmacologie Moléculaire et Cellulaire, Sophia Antipolis, Valbonne, France., Terzolo M; Department of Oncology, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy., Beuschlein F; Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität, Munich, Germany.; Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zurich, Switzerland., Volante M; Department of Oncology, University of Turin at San Luigi Hospital, Orbassano, Turin, Italy., Hantel C; Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität, Munich, Germany.; Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zurich, Switzerland., Lalli E; Université Côte d'Azur, Sophia Antipolis, Valbonne, France.; CNRS UMR7275, Sophia Antipolis, Valbonne, France.; NEOGENEX CNRS International Associated Laboratory, Sophia Antipolis, Valbonne, France.; Institut de Pharmacologie Moléculaire et Cellulaire, Sophia Antipolis, Valbonne, France., Mus-Veteau I; Université Côte d'Azur, Sophia Antipolis, Valbonne, France.; CNRS UMR7275, Sophia Antipolis, Valbonne, France.; NEOGENEX CNRS International Associated Laboratory, Sophia Antipolis, Valbonne, France.; Institut de Pharmacologie Moléculaire et Cellulaire, Sophia Antipolis, Valbonne, France.

Publikováno v: International journal of cancer [Int J Cancer] 2018 Jul 01; Vol. 143 (1), pp. 199-211. Date of Electronic Publication: 2018 Feb 23.