Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hasan Tükenmez"'
Autor:
Hasan Tükenmez, Pardeep Singh, Souvik Sarkar, Melike Çakır, Ana H. Oliveira, Cecilia Lindgren, Karolis Vaitkevicius, Mari Bonde, A. Elisabeth Sauer-Eriksson, Fredrik Almqvist, Jörgen Johansson
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Listeria monocytogenes is a facultative Gram-positive bacterium that causes listeriosis, a severe foodborne disease. We previously discovered that ring-fused 2-pyridone compounds can decrease virulence factor expression in Listeria by bindin
Externí odkaz:
https://doaj.org/article/186a437a48004ee2be0dba97c78a2add
Autor:
Hasan Tükenmez, Souvik Sarkar, Saber Anoosheh, Anastasiia Kruchanova, Isabel Edström, Gregory A. Harrison, Christina L. Stallings, Fredrik Almqvist, Christer Larsson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is a major health threat listed among the top 10 causes of death worldwide. Treatment of multidrug-resistant Mtb requires use of additional second-line drugs that prolong the treatmen
Externí odkaz:
https://doaj.org/article/6c9eede13e994821b7d67d8a10ff5bf1
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163115 (2016)
Enzymes have evolved with highly specific values of their catalytic parameters kcat and KM. This poses fundamental biological questions about the selection pressures responsible for evolutionary tuning of these parameters. Here we are address these q
Externí odkaz:
https://doaj.org/article/f76a02e2b551409cb70c635a7105d551
Autor:
Ana H. Oliveira, Teresa Tiensuu, Duarte Guerreiro, Hasan Tükenmez, Charlotte Dessaux, Francisco García-del Portillo, Conor O’Byrne, Jörgen Johansson
Listeria monocytogenes is a bacterial pathogen capable of causing severe infections but also thriving outside the host. To respond to different stress conditions, L. monocytogenes mainly utilizes the general stress response regulon, which largely is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2da1f67b1d0f41f3f7616c052ed812d
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-211990
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-211990
Autor:
Taylor M. Nye, Hasan Tükenmez, Pardeep Singh, Ana L. Flores-Mireles, Chloe L. P. Obernuefemann, Jerome S. Pinkner, Souvik Sarkar, Mari Bonde, Anders E. G. Lindgren, Karen W. Dodson, Jörgen Johansson, Fredrik Almqvist, Michael G. Caparon, Scott J. Hultgren
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The alarming rise of multidrug-resistant Gram-positive bacteria has precipitated a healthcare crisis, necessitating the development of new antimicrobial therapies. Here we describe a new class of antibiotics based on a ring-fused 2-pyridone backbone,
Autor:
Fredrik Almqvist, Christina L. Stallings, Saber Anoosheh, Gregory A. Harrison, Isabel Edström, Christer Larsson, Hasan Tükenmez, Souvik Sarkar, Anastasiia Kruchanova
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is a major health threat listed among the top 10 causes of death worldwide. Treatment of multidrug-resistant Mtb requires use of additional second-line drugs that prolong the treatment process
Autor:
Hasan Tükenmez, Taylor M. Nye, Mari Bonde, Michael G. Caparon, Fredrik Almqvist, Scott J. Hultgren, Jörgen Johansson
MRSA-1369 is a uropathogenic methicillin-resistant Staphylococcus aureus (MRSA) strain. Here, we present the complete genome sequence of MRSA-1369, which consists of one chromosome (2.87 Mb) and two plasmids (16.68 kb and 3.13 kb). This will serve as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cabca62e3aa4c43ad8d35135ed84e7
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-200828
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-200828
Autor:
Hasan Tükenmez, Ana H. Oliveira, Duarte N. Guerreiro, Francisco García-del Portillo, Jörgen Johansson, Charlotte Dessaux, Teresa Tiensuu, Conor P. O'Byrne
Publikováno v:
Journal of Bacteriology
The survival of microbial cells under changing environmental conditions requires an efficient reprogramming of transcription, often mediated by alternative sigma factors. The Gram-positive human pathogen Listeria monocytogenes senses and responds to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc13fd181373e6da5e8679ea407e575b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190844
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190844
Autor:
Martina Kulén, Christer Larsson, Fredrik Almqvist, K. Syam Krishnan, Erik Chorell, James A. D. Good, Mette R. Hansen, Gregory A. Harrison, Dennis X. Zhu, Jonathan Livny, Scott J. Hultgren, Kelly Flentie, Christina L. Stallings, Anders E. G. Lindgren, Leslie A. Weiss, Torbjörn Wixe, Hasan Tükenmez, Andrew G. Cairns, Christoffer Bengtsson, Souvik Sarkar, Samantha D. Solomon, Miranda E. Schene, Rachel L. Kinsella
Publikováno v:
Proceedings of the National Academy of Sciences. 116:10510-10517
Mycobacterium tuberculosis ( Mtb ) killed more people in 2017 than any other single infectious agent. This dangerous pathogen is able to withstand stresses imposed by the immune system and tolerate exposure to antibiotics, resulting in persistent inf
Autor:
Christer Larsson, Charlotta Sundin, Ramesh Ummanni, Hasan Tükenmez, Mikael Elofsson, Stina Berglund Fick, Isabel Edström
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
High-throughput screening facilities do not generally support biosafety level 3 organisms such as Mycobacterium tuberculosis. To discover not only antibacterials, but also virulence inhibitors with either bacterial or host cell targets, an assay moni