Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Hasan S. Jafri"'
Autor:
Jean Chastre, Bruno François, Marc Bourgeois, Apostolos Komnos, Ricard Ferrer, Galia Rahav, Nicolas De Schryver, Alain Lepape, Iftihar Koksal, Charles-Edouard Luyt, Miguel Sánchez-García, Antoni Torres, Philippe Eggimann, Despoina Koulenti, Thomas L. Holland, Omar Ali, Kathryn Shoemaker, Pin Ren, Julien Sauser, Alexey Ruzin, David E. Tabor, Ahmad Akhgar, Yuling Wu, Yu Jiang, Antonio DiGiandomenico, Susan Colbert, Drieke Vandamme, Frank Coenjaerts, Surbhi Malhotra-Kumar, Leen Timbermont, Antonio Oliver, Olivier Barraud, Terramika Bellamy, Marc Bonten, Herman Goossens, Colin Reisner, Mark T. Esser, Hasan S. Jafri, The COMBACTE-MAGNET EVADE Study Group
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-14 (2022)
Abstract Background Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) in preventing PA nosocomial
Externí odkaz:
https://doaj.org/article/b646d8fc362c477c9d9d20ee008f3057
Autor:
Rachel G. Greenberg, Amy Corneli, John Bradley, John Farley, Hasan S. Jafri, Li Lin, Sumathi Nambiar, Gary J. Noel, Chris Wheeler, Rosemary Tiernan, P. Brian Smith, Jamie Roberts, Daniel K. Benjamin, Jr.
Publikováno v:
Contemporary Clinical Trials Communications, Vol 9, Iss C, Pp 7-12 (2018)
Despite legislation to stimulate pediatric drug development through clinical trials, enrolling children in trials continues to be challenging. Non-investigator (those who have never served as a clinical trial investigator) providers are essential to
Externí odkaz:
https://doaj.org/article/85599ffdeb79468c83dab72b8ba406ac
Autor:
Rachel G. Greenberg, Breck Gamel, Diane Bloom, John Bradley, Hasan S. Jafri, Denise Hinton, Sumathi Nambiar, Chris Wheeler, Rosemary Tiernan, P. Brian Smith, Jamie Roberts, Daniel K. Benjamin, Jr.
Publikováno v:
Contemporary Clinical Trials Communications, Vol 9, Iss C, Pp 33-39 (2018)
Enrollment of children into pediatric clinical trials remains challenging. More effective strategies to improve recruitment of children into trials are needed. This study used in-depth qualitative interviews with parents who were approached to enroll
Externí odkaz:
https://doaj.org/article/750de16bd1904e0d9bd108dd55915219
Autor:
Alexey Ruzin, Olivier Barraud, Li Yu, Bruno François, Miguel Sánchez-Garcia, Philippe Eggimann, Pierre-François Dequin, Pierre-François Laterre, Vincent Huberlant, Lucia Viña, Thierry Boulain, Cedric Bretonniere, Jérôme Pugin, José Trenado, Ana Catalina Hernandez Padilla, Julie Vignaud, Drieke Vandamme, Herman Goossens, Christine Lammens, S. Omar Ali, Kathryn Shoemaker, Pin Ren, Susan Colbert, Terramika Bellamy, Bret R. Sellman, Michael McCarthy, Hasan S. Jafri, Mark T. Esser
Publikováno v:
Journal of clinical microbiology
J Clin Microbiol
J Clin Microbiol
We investigated the performance of the Xpert methicillin-resistant Staphylococcus aureus (MRSA)/S. aureus skin and soft tissue (SSTI) quantitative PCR (qPCR) assay in SAATELLITE, a multicenter, double-blind, phase 2 study of suvratoxumab, a monoclona
Autor:
Saad Nseir, Thierry Boulain, Georgios Baltopoulos, Julie Vignaud, Adel Maamar, Kathryn Shoemaker, Bertrand Souweine, Frédéric Dailler, Pierre-François Laterre, Pedro Moura, Jacques Creteur, Lucia Viña Soria, Terramika Bellamy, Andreas Meier-Hellmann, Alain Mercat, Matthias Gründling, Johann Motsch, Djillali Annane, Paula Ramirez, Christophe Guitton, Antonio Torres Marti, Marco Maggiorini, Tomas Suchy, Alain Lepape, Petr Svoboda, Michal Hanauer, Jan Pachl, Martin Balik, Jérôme Pugin, Jean-Christophe Navellou, Miguel Sánchez-García, Laurent Argaud, Arnaud Desachy, Vasilios Koulouras, Jean-Luc Pagani, Raúl De Pablo Sanchez, Pierre-François Dequin, Carole Schwebel, Ana Catalina Hernandez Padilla, Georgios Filntisis, Patrick Biston, Tomas Vymazal, Juan Carlos Valia, Vadryn Pierre, Frank E. J. Coenjaerts, Frank Wappler, Vladimir Sramek, Fabienne Tamion, Ildikó Krémer, Hasan S Jafri, Zsuzsa Marjanek, Didier Chochrad, Jose Lorente, Marc Simon, Herbert Spapen, Juan Carlos Montejo González, Omar Ali, Cédric Bretonnière, Maria Consuelo Pintado Delgado, Filip Dubovsky, Leen Timbermont, Apostolos Komnos, Christine Lammens, Pin Ren, Tobias Welte, Spyros Zakynthinos, Olivier Barraud, Tomas Hruby, Alain Dive, Herman Goossens, Alexey Ruzin, Marc J. M. Bonten, Ricard Ferrer Roca, Lorenz Reill, Yves Bouckaert, Epaminondas Zakynthinos, Zoltán Szentkereszty, Oliver A. Cornely, Josep Trenado, Antoine Gros, Marc Bourgeois, Ferhat Meziani, Katrin Schmidt, Bruno François, Philippe Eggimann, Ioanna Soultati, Jean-Marc Tadie, Frank Bloos, Agnes Sarkany, Francis Schneider, Susan Colbert, Maria Deja, Mark T. Esser, Gilles Francony, Caroline Rolfes, Martin Nováček, Ana Loza Vazquez, Yuling Wu, Jean-Yves Lefrant, Dolores Escudero, Jean Chastre, Frédéric Foret, René Robert, Vasileios Bekos, Vincent Huberlant, Ioannis Pnevmatikos
Publikováno v:
The lancet infectious diseases
The Lancet. Infectious diseases, Vol. 21, no.9, p. 1313-1323 (2021)
The Lancet. Infectious diseases, Vol. 21, no.9, p. 1313-1323 (2021)
Summary Background Staphylococcus aureus remains a common cause of ventilator-associated pneumonia, with little change in incidence over the past 15 years. We aimed to evaluate the efficacy of suvratoxumab, a monoclonal antibody targeting the α toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b15ccdd46639f0fdf9639d0d5e7f317
https://biblio.vub.ac.be/vubir/(5cde9a53-ceeb-4295-8185-cc8c8f24c7f3).html
https://biblio.vub.ac.be/vubir/(5cde9a53-ceeb-4295-8185-cc8c8f24c7f3).html
Autor:
Ellen Korol, Karissa Johnston, Nathalie Waser, Frangiscos Sifakis, Hasan S Jafri, Mathew Lo, Moe H Kyaw
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83743 (2013)
ImportanceSurgical site infection (SSI) complicates 2-5% of surgeries in the United States. Severity of SSI ranges from superficial skin infection to life-threatening conditions such as severe sepsis, and SSIs are responsible for increased morbidity,
Externí odkaz:
https://doaj.org/article/38a71aea14454d478251a92bd53fcad0
Autor:
Jean Chastre, Bruno François, Marc Bourgeois, Apostolos Komnos, Ricard Ferrer, Galia Rahav, Nicolas De Schryver, Alain Lepape, Iftihar Koksal, Charles-Edouard Luyt, Miguel Sanchez Garcia, Antoni Torres, Thomas L Holland, Omar Ali, Kathryn Shoemaker, Pin Ren, Alexey Ruzin, Yu Jiang, Susan Colbert, Drieke Vandamme, Terramika Bellamy, Colin Reisner, Filip Dubovsky, Hasan S Jafri
Publikováno v:
Open Forum Infectious Diseases
Background Pseudomonas aeruginosa (PA) pneumonia is associated with morbidity and mortality in mechanically ventilated, intensive care unit (MV ICU) patients despite best clinical care. We assessed efficacy, PK, and safety of MEDI3902 in MV ICU subje
Autor:
Hasan S Jafri, Surbhi Malhotra-Kumar, Herman Goossens, Alexey Ruzin, Kathryn Shoemaker, Bruno François, Leen Timbermont, David E. Tabor, Jasmine Coppens, Christine Lammens, Andrey Tovchigrechko, Pin Ren, B.B. Xavier, Bret R. Sellman, Mark T. Esser, Christine Tkaczyk, Michael McCarthy
Publikováno v:
Open Forum Infectious Diseases
Background Suvratoxumab is a human monoclonal antibody that neutralizes S. aureus (SA) alpha toxin (AT). SAATELLITE, a phase 2 study of the safety and efficacy of suvratoxumab for reducing the incidence of SA pneumonia (NCT02296320), was conducted wi
Autor:
José Trenado Álvarez, Pierre-François Dequin, Thierry Boulain, Kathryn Shoemaker, Vincent Huberlant, Lorin Roskos, Bruno François, Lucia Viña, Vadryn Pierre, Pierre-François Laterre, Cédric Bretonnière, Jérôme Pugin, Philippe Eggimann, Terramika Bellamy, Martha Hernandez-Illas, Anis A. Khan, Yuling Wu, Nancy Lee, Miguel Sánchez García, Hasan S Jafri, Omar Ali, Alexey Ruzin, Susan Colbert
Publikováno v:
Open Forum Infectious Diseases
Background Suvratoxumab (suvra), an extended half-life (~80 days), Staphylococcus aureus (SA) alpha toxin-neutralizing IgG monoclonal antibody, is under investigation for prevention of SA pneumonia in patients on mechanical ventilation (MV). We chara
Autor:
Bruno François, Marc J. M. Bonten, Philippe Eggiman, Pierre-François Laterre, Miguel Angel Gomez Sanchez, Antoni Torres, Herman Goosens, Brian Bishop, Hasan S. Jafri, Jean Chastre, Mark T. Esser
Publikováno v:
Clinical Infectious Diseases. 63:S46-S51
The Innovative Medicines Initiative-funded COMBACTE consortium fosters academic-industry partnership in pioneering studies to combat serious bacterial infections. We describe how this partnership is advancing the development of 2 monoclonal antibodie