Knockdown of Annexin A1 induces apoptosis, causing G2/M arrest and facilitating phagocytosis activity in human leukemia cell lines

Autor: Hasan Masyitah, Kumolosasi Endang, Jantan Ibrahim, Jasamai Malina, Nazarudin Norlaili

Publikováno v: Acta Pharmaceutica, Vol 72, Iss 1, Pp 109-122 (2022)

Annexin A1 (ANXA1) is an endogenous protein involved in the control of proliferation, cell cycle, phagocytosis, and apoptosis in several types of cancer. To investigate the effects of ANXA1 knockdown in leukemia cells, transfection with specific ANXA

Externí odkaz: https://doaj.org/article/5d6b69584270430eb028fd66e0e116b3

Knockdown of Annexin A1 induces apoptosis, causing G2/M arrest and facilitating phagocytosis activity in human leukemia cell lines.

Autor: Hasan M; Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur Malaysia., Kumolosasi E; Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur Malaysia., Jantan I; Institute of Systems Biology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia., Jasamai M; Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur Malaysia., Nazarudin N; Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur Malaysia.

Publikováno v: Acta pharmaceutica (Zagreb, Croatia) [Acta Pharm] 2021 Aug 30; Vol. 72 (1), pp. 109-122. Date of Electronic Publication: 2021 Aug 30 (Print Publication: 2022).