Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hasan M. S. Ibrahim"'
Autor:
Anna Dimitriou, Daniel Paape, Christopher M Woodley, Ulrich Zachariae, Anthonius A. Eze, Simone Weyand, Ibrahim A. Teka, Ali H. Alghamdi, Richard R. Tidwell, Arvind Kumar, Jane C. Munday, Juan F. Quintana, Mark Carrington, Mohammed I. Al-Salabi, Paul M. O'Neill, Laura F Anderson, Maria Esther Martin Abril, Harry P. de Koning, Teresa Sprenger, Hasan M. S. Ibrahim, Fredrik Svensson, Simon Gudin, Fabian Hulpia, Patrik Milic, Chinyere E Okpara, Gustavo D. Campagnaro, Dominik Gurvic, Graeme Smart, David W. Boykin, Christophe Dardonville, Luca Settimo, Siu Pui Ying Kelly, Laura Watson, Joanna Wielinska, Mark C. Field
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa648917f3111794e8be1fa4dd747110
https://doi.org/10.7554/elife.56416.sa2
https://doi.org/10.7554/elife.56416.sa2
Autor:
Harry P. de Koning, Ibrahim A. Teka, Hasan M. S. Ibrahim, Christopher M Woodley, Simon Gudin, Patrik Mili, Arvind Kumar, Daniel Paape, Fredrik Svensson, Fabian Hulpia, Jane C. Munday, Mark Carrington, Mohammed I. Al-Salabi, Dominik Gurvic, Laura F Anderson, Christophe Dardonville, David W. Boykin, Chinyere E Okpara, Ali H. Alghamdi, Luca Settimo, Laura Watson, Maria Esther Martin Abril, Joanna Wielinska, Gustavo D. Campagnaro, Graeme Smart, Ulrich Zachariae, Anthonius A. Eze, Richard R. Tidwell, Anna Dimitriou, Siu Pui Ying Kelly, Paul M. O'Neill
Mutations in the Trypanosoma brucei aquaporin AQP2 are associated with resistance to pentamidine and melarsoprol. We show that TbAQP2 but not TbAQP3 was positively selected for increased pore size from a common ancestor aquaporin. We demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12a2c3019e9ca4c7a9a0aacc54e2b6b
Autor:
Paul M. O'Neill, Harry P. de Koning, Anna Dimitriou, Ulrich Zachariae, Joanna Wielinska, Arvind Kumar, Anthonius A. Eze, Mark C. Field, Chinyere E Okpara, Juan F. Quintana, Richard R. Tidwell, Simone Weyand, Luca Settimo, Siu Pui Ying Kelly, Christopher M Woodley, Dominik Gurvic, Ibrahim A. Teka, Mohammed I. Al-Salabi, Fredrik Svensson, Fabian Hulpia, Ali H. Alghamdi, Patrik Milic, Teresa Sprenger, Hasan M. S. Ibrahim, David W. Boykin, Laura Watson, Laura F Anderson, Daniel Paape, Mark Carrington, Maria Esther Martin Abril, Simon Gudin, Gustavo D. Campagnaro, Graeme Smart, Jane C. Munday, Christophe Dardonville
Publikováno v:
ELIFE
eLife
eLife, Vol 9 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
eLife
eLife, Vol 9 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Mutations in the Trypanosoma brucei aquaporin AQP2 are associated with resistance to pentamidine and melarsoprol. We show that TbAQP2 but not TbAQP3 was positively selected for increased pore size from a common ancestor aquaporin. We demonstrate that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a8612e3af4438b62845ec7d02b257f
https://biblio.ugent.be/publication/8671473
https://biblio.ugent.be/publication/8671473
Publikováno v:
EPH - International Journal of Applied Science. 1:1-7
Intestinal d protozoan parasites are still major public health problems in the world, particularly in developing countries. This retrospective study was conducted using data obtained from the Department of Parasitology of Sebha Central Laboratory in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cff3633be0e6f95001d4f516baa35ab
https://doi.org/10.53555/eijas.v1i4.18
https://doi.org/10.53555/eijas.v1i4.18
Autor:
Harry P. de Koning, Juma A. M. Ali, Ibrahim A. Teka, Nasser El-Sabbagh, Boris Rodenko, Mohammed I. Al-Salabi, Martin J. Wanner, Gerrit-Jan Koomen, Hasan M. S. Ibrahim, William Ho
Publikováno v:
ACS Medicinal Chemistry Letters, 2(12), 901-906. American Chemical Society
Given the pressing need for new antiprotozoal drugs without cross-resistance with current (failing) chemotherapy, we have explored 3-tridecylpyridinium alkaloids (3TPAs), derivatives of viscosamine, as antiparasitic agents. We have developed a simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2154ce7ce26fb648d184d6130812d21b
https://doi.org/10.1021/ml200160k
https://doi.org/10.1021/ml200160k
Autor:
Harry P. de Koning, Chatchawan Changtam, Apichart Suksamrarn, Hasan M. S. Ibrahim, M. Sohail Sajid, Matthew K. Gould
Publikováno v:
European Journal of Medicinal Chemistry. 45:941-956
The natural curcuminoids curcumin (1), demethoxycurcumin (2) and bisdemethoxycurcumin (3) have been chemically modified to give 46 analogs and 8 pairs of 1:1 mixture of curcuminoid analogs and these parent curcuminoids and their analogs were assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7623a1dde4190f52aa11b2de0e660316
https://doi.org/10.1016/j.ejmech.2009.11.035
https://doi.org/10.1016/j.ejmech.2009.11.035
Autor:
Darren J. Creek, Harry P. de Koning, Karl Burgess, Dong-Hyun Kim, Apichart Suksamrarn, Chatchawan Changtam, Abdulsalam A. M. Alkhaldi, Michael P. Barrett, Hasan M. S. Ibrahim, Neils B. Quashie
Publikováno v:
Molecular pharmacology. 87(3)
We have previously reported that curcumin analogs with a C7 linker bearing a C4-C5 olefinic linker with a single keto group at C3 (enone linker) display midnanomolar activity against the bloodstream form of Trypanosoma brucei. However, no clear indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2b8a9d401a0a83d6e1c3501190e29d
https://pubmed.ncbi.nlm.nih.gov/25527638
https://pubmed.ncbi.nlm.nih.gov/25527638
Autor:
Harry P. de Koning, Roger Escale, Abdulsalam A. M. Alkhaldi, Terry K. Smith, Henri Vial, Mohammed I. Al-Salabi, Hasan M. S. Ibrahim, Neils B. Quashie, Nasser El Sabbagh
Publikováno v:
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2011, 66, pp.111-125. ⟨10.1093/jac/dkq401⟩
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2011, 66, pp.111-125. ⟨10.1093/jac/dkq401⟩
International audience; OBJECTIVES: to investigate the anti-kinetoplastid activity of choline-derived analogues with previously reported antimalarial efficacy. METHODS: from an existing choline analogue library, seven antimalarial compounds, represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cfbd1f541159cac6128e6b5c46e1b7
https://hal.archives-ouvertes.fr/hal-00569942
https://hal.archives-ouvertes.fr/hal-00569942