Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Hasan Korkaya"'
Autor:
Fulya Koksalar Alkan, Ahmet Burak Caglayan, Hilmi Kaan Alkan, Elayne Benson, Yunus Emre Gunduz, Ozge Sensoy, Serdar Durdagi, Elbrus Zarbaliyev, Greg Dyson, Hadeel Assad, Austin Shull, Ahmed Chadli, Huidong Shi, Gurkan Ozturk, Hasan Korkaya
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Triple negative breast cancer (TNBC) subtype is characterized with higher EMT/stemness properties and immune suppressive tumor microenvironment (TME). Women with advanced TNBC exhibit aggressive disease and have limited treatment options. Al
Externí odkaz:
https://doaj.org/article/4c7feb8b8c1e4a10878a6afdd1f9525f
Autor:
Chaitanya A. Patwardhan, Vamsi Krishna Kommalapati, Taoufik Llbiyi, Digvijay Singh, Eyad Alfa, Anatolij Horuzsko, Hasan Korkaya, Siva Panda, Christopher A. Reilly, Vladimir Popik, Ahmed Chadli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Heat shock protein 90 (Hsp90) and its co-chaperones promote cancer, and targeting Hsp90 holds promise for cancer treatment. Most of the efforts to harness this potential have focused on targeting the Hsp90 N-terminus ATP binding site. Althou
Externí odkaz:
https://doaj.org/article/9e5b533d54cf49d1844e10517fac6d50
Autor:
Nada H. Eisa, Vincent M. Crowley, Asif Elahi, Vamsi Krishna Kommalapati, Michael A. Serwetnyk, Taoufik Llbiyi, Sumin Lu, Kashish Kainth, Yasmeen Jilani, Daniela Marasco, Abdeljabar El Andaloussi, Sukyeong Lee, Francis T.F. Tsai, Paulo C. Rodriguez, David Munn, Esteban Celis, Hasan Korkaya, Abdessamad Debbab, Brian Blagg, Ahmed Chadli
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108308- (2023)
Summary: Low response rates and immune-related adverse events limit the remarkable impact of cancer immunotherapy. To improve clinical outcomes, preclinical studies have shown that combining immunotherapies with N-terminal Hsp90 inhibitors resulted i
Externí odkaz:
https://doaj.org/article/f4ba062b1eb84919b99e30fb877c3d61
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/c64a1bd5ed074ad7ad926bb9121cd138
Autor:
Raziye Piranlioglu, EunMi Lee, Maria Ouzounova, Roni J. Bollag, Alicia H. Vinyard, Ali S. Arbab, Daniela Marasco, Mustafa Guzel, John K. Cowell, Muthushamy Thangaraju, Ahmed Chadli, Khaled A. Hassan, Max S. Wicha, Esteban Celis, Hasan Korkaya
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Dissemination of tumor cells from the primary site is an early event. Here, the authors show that the early disseminated tumor cells are actively cleared by the host cytotoxic T lymphocytes induced by the primary tumor and that infiltration of granul
Externí odkaz:
https://doaj.org/article/ab8309125be1466c9f20adaacc94d582
Autor:
Hasan Korkaya, Sandra Orsulic
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/be328100218d4a3c823b75613145d7ae
Autor:
Xiaolin Yu, Sharad Ghamande, Haitao Liu, Lu Xue, Shuhua Zhao, Wenxi Tan, Lijing Zhao, Shou-Ching Tang, Daqing Wu, Hasan Korkaya, Nita J. Maihle, Hong Yan Liu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 10, Iss , Pp 317-330 (2018)
HER family members are interdependent and functionally compensatory. Simultaneously targeting EGFR/HER2/HER3 by antibody combinations has demonstrated superior treatment efficacy over targeting one HER receptor. However, antibody combinations have th
Externí odkaz:
https://doaj.org/article/59b967c81b704f36b46f263e8b73b15d
Autor:
Maria Ouzounova, Eunmi Lee, Raziye Piranlioglu, Abdeljabar El Andaloussi, Ravindra Kolhe, Mehmet F. Demirci, Daniela Marasco, Iskander Asm, Ahmed Chadli, Khaled A. Hassan, Muthusamy Thangaraju, Gang Zhou, Ali S. Arbab, John K. Cowell, Hasan Korkaya
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Myeloid-derived suppressive cells (MDSCs) promote metastasis. Here, the authors show that the monocytic MDSCs subset promotes epithelial to mesenchymal transition at the primary site while the granulocytic subset promotes the reverse transition at th
Externí odkaz:
https://doaj.org/article/fd3befe0433a4fdaa9773cbb10f54358
Autor:
Huidong Shi, David H. Munn, Shou-Ching Tang, Stefan Ambs, Arun Sreekumar, Muthusamy Thangaraju, Shuang Huang, Hong-Bo Xin, Libin Deng, Hasan Korkaya, Tim H.M. Huang, Katie Chiou, Jiseok Choi, Fang Shi, Ravindra Kolhe, Pei-Yin Hsu, Lirong Pei, Austin Y. Shull, Maria Ouzounova, Jaejik Kim, Qimei Han, Jeong-Hyeon Choi, Eun-Joon Lee, Franklin Gu, Satish K. Noonepalle
Supplementary Table 1: List of primers used for quantitative real time PCR. Supplementary Table. 2: List of primers used for construction of pGL2 and pMIR reporter plasmids. Supplementary Table. 3: List of primers used to generate PCR amplicons for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fed68c14a16cfbab8a3970f33ff2b3
https://doi.org/10.1158/2326-6066.22538461.v1
https://doi.org/10.1158/2326-6066.22538461.v1
Autor:
Muthusamy Thangaraju, Vadivel Ganapathy, Bal L. Lokeshwar, Vinata B. Lokeshwar, Puttur D. Prasad, Santhakumar Manicassamy, Nagendra Singh, Hasan Korkaya, Pamela M. Martin, Nikhil Patel, Ravirajsinh N. Jedeja, Pachiappan Arjunan, Sarrah L. Hasanali, Daley S. Morera, Pragya Rajpurohit, Adrienne Lester, Utkarsh Parwal, Kavin Tamizhmani, Sabarish Ramachandran, Allison E. Bridges
DNA damage, induced by either chemical carcinogens or environmental pollutants, plays an important role in the initiation of colorectal cancer. DNA repair processes, however, are involved in both protecting against cancer formation, and also contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac87d6c2f58e7b2067bca443489ed66
https://doi.org/10.1158/1541-7786.c.6545298.v1
https://doi.org/10.1158/1541-7786.c.6545298.v1